3K7A

Crystal Structure of an RNA polymerase II-TFIIB complex

Summary for 3K7A

Entry DOI	10.2210/pdb3k7a/pdb
Descriptor	DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, ... (12 entities in total)
Functional Keywords	rna polymerase ii, tfiib, transcription, dna-binding, dna-directed rna polymerase, isopeptide bond, magnesium, metal-binding, nucleotidyltransferase, nucleus, phosphoprotein, transferase, zinc-finger, dna damage, dna repair, transcription regulation
Biological source	Saccharomyces cerevisiae (yeast) More
Cellular location	Nucleus: P04050 P29055 P08518 P16370 P20434 P20436 P27999 P38902 Nucleus, nucleolus: P40422 P22139 Cytoplasm: P20435
Total number of polymer chains	11
Total formula weight	508472.00
Authors	Liu, X.,Bushnell, D.A.,Wang, D.,Calero, G.,Kornberg, R.D. (deposition date: 2009-10-12, release date: 2009-11-24, Last modification date: 2023-09-06)
Primary citation	Liu, X.,Bushnell, D.A.,Wang, D.,Calero, G.,Kornberg, R.D. Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism. Science, 327:206-209, 2010 Cited by PubMed: 19965383 DOI: 10.1126/science.1182015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8 Å)

Structure validation