8GXQ

PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state

This is a non-PDB format compatible entry.

Summary for 8GXQ

• Entry DOI: 10.2210/pdb8gxq/pdb
• Related: 8GXS
• EMDB information: 33867 33885 33886 34215 34255 34256 34257 34359 34360
• Descriptor: DNA (228-mer), Transcription initiation factor TFIID subunit 2, Transcription initiation factor IIE subunit beta, ... (80 entities in total)
• Functional Keywords: pic, mediator, transcription initiation, +1 nucleosome, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 87
• Total formula weight: 4274920.15

Authors

Chen, X.,Wang, X.,Liu, W.,Ren, Y.,Qu, X.,Li, J.,Yin, X.,Xu, Y. (deposition date: 2022-09-21, release date: 2022-11-02)

• Primary citation: Chen, X.,Wang, X.,Liu, W.,Ren, Y.,Qu, X.,Li, J.,Yin, X.,Xu, Y.; Structures of +1 nucleosome-bound PIC-Mediator complex.; Science, 378:62-68, 2022; PubMed: 36201575; DOI: 10.1126/science.abn8131

Experimental method

ELECTRON MICROSCOPY (5.04 Å)