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2H8A
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2h8a
STRUCTURE OF MICROSOMAL GLUTATHIONE TRANSFERASE 1 IN COMPLEX WITH GLUTATHIONE
Descriptor:Microsomal glutathione S-transferase 1 (E.C.2.5.1.18)
Authors:Hebert, H.
Deposit date:2006-06-07
Release date:2007-05-22
Modification date:2012-03-21
Method:ELECTRON CRYSTALLOGRAPHY (3.2 Å)
Cite:Structural basis for detoxification and oxidative stress protection in membranes.
J.Mol.Biol., 360, 2006
2PNO
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2pno
CRYSTAL STRUCTURE OF HUMAN LEUKOTRIENE C4 SYNTHASE
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Ago, H., Kanaoka, Y., Irikura, D., Lam, B.K., Shimamura, T., Austen, K.F., Miyano, M.
Deposit date:2007-04-24
Release date:2007-08-07
Modification date:2011-12-07
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis
Nature, 448, 2007
2Q7M
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2q7m
CRYSTAL STRUCTURE OF HUMAN FLAP WITH MK-591
Descriptor:Arachidonate 5-lipoxygenase-activating protein
Authors:Ferguson, A.D.
Deposit date:2007-06-07
Release date:2007-08-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
Science, 317, 2007
2Q7R
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2q7r
CRYSTAL STRUCTURE OF HUMAN FLAP WITH AN IODINATED ANALOG OF MK-591
Descriptor:Arachidonate 5-lipoxygenase-activating protein
Authors:Ferguson, A.D.
Deposit date:2007-06-07
Release date:2007-08-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
Science, 317, 2007
2UUH
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2uuh
CRYSTAL STRUCTURE OF HUMAN LEUKOTRIENE C4 SYNTHASE IN COMPLEX WITH SUBSTRATE GLUTATHIONE
Descriptor:LEUKOTRIENE C4 SYNTHASE (E.C.4.4.1.20)
Authors:Martinez Molina, D., Wetterholm, A., Kohl, A., Mccarthy, A.A., Niegowski, D., Ohlson, E., Hammarberg, T., Eshaghi, S., Haeggstrom, J.Z., Nordlund, P.
Deposit date:2007-03-02
Release date:2007-07-17
Modification date:2011-12-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase.
Nature, 448, 2007
2UUI
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2uui
CRYSTAL STRUCTURE OF HUMAN LEUKOTRIENE C4 SYNTHASE
Descriptor:LEUKOTRIENE C4 SYNTHASE (E.C.4.4.1.20)
Authors:Martinez Molina, D., Wetterholm, A., Kohl, A., Mccarthy, A.A., Niegowski, D., Ohlson, E., Hammarberg, T., Eshaghi, S., Haeggstrom, J.Z., Nordlund, P.
Deposit date:2007-03-02
Release date:2007-07-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase.
Nature, 448, 2007
3B29
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3b29
HUMAN LEUKOTRIENE C4 SYNTHASE IN COMPLEX WITH DODECYL-BETA-D-SELENOMALTOSIDE
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Saino, H., Ago, H., Miyano, M.
Deposit date:2011-07-22
Release date:2011-12-14
Modification date:2012-05-02
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-beta-D-selenomaltoside
Acta Crystallogr.,Sect.F, 67, 2011
3DWW
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3dww
ELECTRON CRYSTALLOGRAPHIC STRUCTURE OF HUMAN MICROSOMAL PROSTAGLANDIN E SYNTHASE 1
Descriptor:Prostaglandin E synthase (E.C.5.3.99.3)
Authors:Hebert, H., Jegerschold, C.
Deposit date:2008-07-23
Release date:2009-07-28
Modification date:2012-03-21
Method:ELECTRON CRYSTALLOGRAPHY (3.5 Å)
Cite:Structural basis for induced formation of the inflammatory mediator prostaglandin E2
Proc.Natl.Acad.Sci.USA, 105, 2008
3HKK
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3hkk
STRUCTURE OF HUMAN LEUKOTRIENE C4 SYNTHASE IN COMPLEX WITH GLUTATHIONE SULFONATE
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Rinaldo-Matthis, A., Haeggstrom, J.Z.
Deposit date:2009-05-24
Release date:2010-05-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Pre-steady state kinetics of human Leukotriene C4 synthase
To be Published
3LEO
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3leo
STRUCTURE OF HUMAN LEUKOTRIENE C4 SYNTHASE MUTANT R31Q IN COMPLEX WITH GLUTATHIONE
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Niegowski, D., Martinez-Molina, D., Rinaldo-Matthis, A., Nordlund, P., Haeggstrom, J.
Deposit date:2010-01-15
Release date:2010-10-27
Modification date:2012-12-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Arginine 104 is a key catalytic residue in leukotriene C4 synthase.
J.Biol.Chem., 285, 2010
3PCV
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3pcv
CRYSTAL STRUCTURE ANALYSIS OF HUMAN LEUKOTRIENE C4 SYNTHASE AT 1.9 ANGSTROM RESOLUTION
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Saino, H., Ago, H., Miyano, M.
Deposit date:2010-10-22
Release date:2011-03-16
Modification date:2011-12-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The catalytic architecture of leukotriene C4 synthase with two arginine residues
J.Biol.Chem., 286, 2011
4AL0
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4al0
CRYSTAL STRUCTURE OF HUMAN PS-1
Descriptor:PROSTAGLANDIN E SYNTHASE (E.C.5.3.99.3)
Authors:Sjogren, T., Nord, J., Ek, M., Johansson, P., Liu, G., Geschwindner, S.
Deposit date:2012-02-29
Release date:2013-02-06
Modification date:2013-03-20
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Crystal Structure of Microsomal Prostaglandin E2 Synthase Provides Insight Into Diversity in the Mapeg Superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AL1
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4al1
CRYSTAL STRUCTURE OF HUMAN PS-1 GSH-ANALOG COMPLEX
Descriptor:PROSTAGLANDIN E SYNTHASE (E.C.5.3.99.3)
Authors:Sjogren, T., Nord, J., Ek, M., Johansson, P., Liu, G., Geschwindner, S.
Deposit date:2012-02-29
Release date:2013-02-06
Modification date:2013-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Microsomal Prostaglandin E2 Synthase Provides Insight Into Diversity in the Mapeg Superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BPM
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4bpm
CRYSTAL STRUCTURE OF A HUMAN INTEGRAL MEMBRANE ENZYME
Descriptor:PROSTAGLANDIN E SYNTHASE, FUSION PEPTIDE (E.C.5.3.99.3)
Authors:Li, D., Wang, M., Olieric, V., Caffrey, M.
Deposit date:2013-05-27
Release date:2014-04-16
Modification date:2014-05-14
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.
Cryst.Growth Des., 14, 2014
4J7T
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4j7t
HUMAN LTC4 SYNTHASE IN COMPLEX WITH PRODUCT ANALOGS - IMPLICATIONS FOR ENZYME CATALYSIS
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Niegowski, D., Rinaldo-Matthis, A., Haeggstrom, J.Z.
Deposit date:2013-02-14
Release date:2014-01-01
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4J7Y
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4j7y
HUMAN LTC4 SYNTHASE IN COMPLEX WITH PRODUCT ANALOGS - IMPLICATIONS FOR ENZYME CATALYSIS
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Niegowski, D., Rinaldo-Matthis, A., Haeggstrom, J.Z.
Deposit date:2013-02-14
Release date:2014-01-01
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4JC7
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4jc7
HUMAN LTC4 SYNTHASE IN COMPLEX WITH PRODUCT ANALOGS - IMPLICATIONS FOR ENZYME CATALYSIS
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Niegowski, D., Rinaldo-Matthis, A., Haeggstrom, J.Z.
Deposit date:2013-02-21
Release date:2014-01-01
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4JCZ
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4jcz
HUMAN LTC4 SYNTHASE IN COMPLEX WITH PRODUCT ANALOGS - IMPLICATIONS FOR ENZYME CATALYSIS
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Niegowski, D., Rinaldo-Matthis, A., Haeggstrom, J.Z.
Deposit date:2013-02-22
Release date:2014-01-01
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
4JRZ
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4jrz
HUMAN LTC4 SYNTHASE IN COMPLEX WITH PRODUCT ANALOGS - IMPLICATIONS FOR ENZYME CATALYSIS
Descriptor:Leukotriene C4 synthase (E.C.4.4.1.20)
Authors:Niegowski, D., Rinaldo-Matthis, A., Haeggstrom, J.Z.
Deposit date:2013-03-22
Release date:2014-01-01
Modification date:2014-03-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM.
J.Biol.Chem., 289, 2014
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entries available on 2014-09-10
00:00 UTC / 09:00 JST