2PNO

Crystal structure of human leukotriene C4 synthase

Summary for 2PNO

Entry DOI	10.2210/pdb2pno/pdb
Descriptor	Leukotriene C4 synthase, GLUTATHIONE, DODECYL-BETA-D-MALTOSIDE (3 entities in total)
Functional Keywords	membrane protein, helix bundle, homo trimer, mgst, mapeg, lyase
Biological source	Homo sapiens (human)
Cellular location	Nucleus outer membrane; Multi-pass membrane protein: Q16873
Total number of polymer chains	12
Total formula weight	241731.40
Authors	Ago, H.,Kanaoka, Y.,Irikura, D.,Lam, B.K.,Shimamura, T.,Austen, K.F.,Miyano, M. (deposition date: 2007-04-24, release date: 2007-08-07, Last modification date: 2024-03-13)
Primary citation	Ago, H.,Kanaoka, Y.,Irikura, D.,Lam, B.K.,Shimamura, T.,Austen, K.F.,Miyano, M. Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis Nature, 448:609-612, 2007 Cited by PubMed: 17632548 DOI: 10.1038/nature05936 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation