3DWW
Electron crystallographic structure of human microsomal prostaglandin E synthase 1
Summary for 3DWW
| Entry DOI | 10.2210/pdb3dww/pdb |
| Related | 2h8a |
| Descriptor | Prostaglandin E synthase, GLUTATHIONE (2 entities in total) |
| Functional Keywords | membrane protein, four helix bundle, isomerase, membrane, transmembrane |
| Biological source | Homo sapiens (Human) |
| Cellular location | Membrane; Multi-pass membrane protein: O14684 |
| Total number of polymer chains | 3 |
| Total formula weight | 54778.58 |
| Authors | Hebert, H.,Jegerschold, C. (deposition date: 2008-07-23, release date: 2009-07-28, Last modification date: 2024-03-20) |
| Primary citation | Jegerschold, C.,Pawelzik, S.C.,Purhonen, P.,Bhakat, P.,Gheorghe, K.R.,Gyobu, N.,Mitsuoka, K.,Morgenstern, R.,Jakobsson, P.J.,Hebert, H. Structural basis for induced formation of the inflammatory mediator prostaglandin E2 Proc.Natl.Acad.Sci.USA, 105:11110-11115, 2008 Cited by PubMed: 18682561DOI: 10.1073/pnas.0802894105 PDB entries with the same primary citation |
| Experimental method | ELECTRON CRYSTALLOGRAPHY (3.5 Å) |
Structure validation
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