2UUI

Crystal structure of Human Leukotriene C4 Synthase

Summary for 2UUI

Entry DOI	10.2210/pdb2uui/pdb
Related	2UUH
Descriptor	LEUKOTRIENE C4 SYNTHASE, NICKEL (II) ION, DODECYL-BETA-D-MALTOSIDE, ... (6 entities in total)
Functional Keywords	leukotriene signalling, leukotriene biosynthesis, membrane, eicosanoid, transmembrane, membrane protein, apo, lyase, mapeg, human, ltc4s, enzyme, trimer
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus outer membrane; Multi-pass membrane protein: Q16873
Total number of polymer chains	1
Total formula weight	22390.92
Authors	Martinez Molina, D.,Wetterholm, A.,Kohl, A.,McCarthy, A.A.,Niegowski, D.,Ohlson, E.,Hammarberg, T.,Eshaghi, S.,Haeggstrom, J.Z.,Nordlund, P. (deposition date: 2007-03-02, release date: 2007-07-17, Last modification date: 2011-07-13)
Primary citation	Martinez Molina, D.,Wetterholm, A.,Kohl, A.,Mccarthy, A.A.,Niegowski, D.,Ohlson, E.,Hammarberg, T.,Eshaghi, S.,Haeggstrom, J.Z.,Nordlund, P. Structural Basis for Synthesis of Inflammatory Mediators by Human Leukotriene C4 Synthase. Nature, 448:613-, 2007 Cited by PubMed: 17632546 DOI: 10.1038/NATURE06009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation