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1A28
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1a28
HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN
Descriptor:PROGESTERONE RECEPTOR, PROGESTERONE
Authors:Sigler, P.B., Williams, S.P.
Deposit date:1998-01-19
Release date:1998-07-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structure of progesterone complexed with its receptor.
Nature, 393, 1998
1A52
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1a52
ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED TO ESTRADIOL
Descriptor:ESTROGEN RECEPTOR, ESTRADIOL, GOLD ATOM
Authors:Tanenbaum, D.M., Wang, Y., Sigler, P.B.
Deposit date:1998-02-19
Release date:1998-09-16
Modification date:2011-11-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BSX
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1bsx
STRUCTURE AND SPECIFICITY OF NUCLEAR RECEPTOR-COACTIVATOR INTERACTIONS
Descriptor:PROTEIN (THYROID HORMONE RECEPTOR BETA)
Authors:Wagner, R.L., Darimont, B.D., Apriletti, J.W., Stallcup, M.R., Kushner, P.J., Baxter, J.D., Fletterick, R.J., Yamamoto, K.R.
Deposit date:1998-08-31
Release date:1999-08-26
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure and specificity of nuclear receptor-coactivator interactions.
Genes Dev., 12, 1998
1DB1
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1db1
CRYSTAL STRUCTURE OF THE NUCLEAR RECEPTOR FOR VITAMIN D COMPLEXED TO VITAMIN D
Descriptor:VITAMIN D NUCLEAR RECEPTOR
Authors:Rochel, N., Wurtz, J.M., Mitschler, A., Klaholz, B., Moras, D.
Deposit date:1999-11-02
Release date:2000-01-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand.
Mol.Cell, 5, 2000
1E3G
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1e3g
HUMAN ANDROGEN RECEPTOR LIGAND BINDING IN COMPLEX WITH THE LIGAND METRIBOLONE (R1881)
Descriptor:ANDROGEN RECEPTOR
Authors:Matias, P.M., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A., Basler, S., Schafer, M., Ruff, M., Egner, U., Carrondo, M.A.
Deposit date:2000-06-14
Release date:2001-06-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Evidence for Ligand Specificity in the Binding Domain of the Human Androgen Receptor. Implications for Pathogenic Gene Mutations
J.Biol.Chem., 275, 2000
1E3K
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1e3k
HUMAN PROGESTERON RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH THE LIGAND METRIBOLONE (R1881)
Descriptor:PROGESTERONE RECEPTOR
Authors:Matias, P.M., Donner, P., Coelho, R., Thomaz, M., Peixoto, C., Macedo, S., Otto, N., Joschko, S., Scholz, P., Wegg, A., Basler, S., Schafer, M., Egner, U., Carrondo, M.A.
Deposit date:2000-06-19
Release date:2001-06-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Evidence for Ligand Specificity in the Binding Domain of the Human Androgen Receptor. Implications for Pathogenic Gene Mutations
J.Biol.Chem., 275, 2000
1ERE
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1ere
HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL
Descriptor:ESTROGEN RECEPTOR, ESTRADIOL
Authors:Brzozowski, A.M., Pike, A.C.W.
Deposit date:1997-09-08
Release date:1998-09-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular basis of agonism and antagonism in the oestrogen receptor.
Nature, 389, 1997
1ERR
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1err
HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH RALOXIFENE
Descriptor:ESTROGEN RECEPTOR, CARBOXYMETHYL GROUP, RALOXIFENE
Authors:Brzozowski, A.M., Pike, A.C.W.
Deposit date:1997-09-08
Release date:1998-09-16
Modification date:2013-05-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of agonism and antagonism in the oestrogen receptor.
Nature, 389, 1997
1EXA
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1exa
ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.
Descriptor:HUMAN RETINOIC ACID RECEPTOR HRARGAMMA
Authors:Klaholz, B.P., Mitschler, A., Belema, M., Zusi, C., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-05-02
Release date:2000-06-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EXX
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1exx
ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395.
Descriptor:HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395.
Authors:Klaholz, B.P., Mitschler, A., Belema, M., Zusi, C., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-05-05
Release date:2000-06-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma.
Proc.Natl.Acad.Sci.USA, 97, 2000
1FBY
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1fby
CRYSTAL STRUCTURE OF THE HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO 9-CIS RETINOIC ACID
Descriptor:RETINOIC ACID RECEPTOR RXR-ALPHA
Authors:Egea, P.F., Mitschler, A., Rochel, N., Ruff, M., Chambon, P., Moras, D.
Deposit date:2000-07-17
Release date:2000-07-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid.
EMBO J., 19, 2000
1FCX
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1fcx
ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID BMS184394
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1
Authors:Klaholz, B.P., Mitschler, A., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1FCY
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1fcy
ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1
Authors:Klaholz, B.P., Mitschler, A., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1FCZ
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1fcz
ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE PANAGONIST RETINOID BMS181156
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1/INHIBITOR COMPLEX
Authors:Klaholz, B.P., Mitschler, A., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2000-09-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
J.Mol.Biol., 302, 2000
1FD0
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1fd0
ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID SR11254
Descriptor:RETINOIC ACID RECEPTOR GAMMA-1/INHIBITOR COMPLEX
Authors:Klaholz, B.P., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-07-19
Release date:2002-09-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:C-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity.
Structure, 10, 2002
1G1U
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1g1u
THE 2.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE RXRALPHA LIGAND BINDING DOMAIN IN TETRAMER IN THE ABSENCE OF LIGAND
Descriptor:RETINOIC ACID RECEPTOR RXR-ALPHA
Authors:Gampe Jr., R.T., Montana, V.G., Lambert, M.H., Wisely, G.B., Milburn, M.V., Xu, H.E.
Deposit date:2000-10-13
Release date:2001-04-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix.
Genes Dev., 14, 2000
1G2N
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1g2n
CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF THE ULTRASPIRACLE PROTEIN USP, THE ORTHOLOG OF RXRS IN INSECTS
Descriptor:ULTRASPIRACLE PROTEIN
Authors:Billas, I.M.L., Moulinier, L., Rochel, N., Moras, D., Structural Proteomics in Europe (SPINE)
Deposit date:2000-10-20
Release date:2001-04-21
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.
J.Biol.Chem., 276, 2001
1G50
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1g50
CRYSTAL STRUCTURE OF A WILD TYPE HER ALPHA LBD AT 2.9 ANGSTROM RESOLUTION
Descriptor:ESTROGEN RECEPTOR
Authors:Eiler, S., Gangloff, M., Duclaud, S., Moras, D., Ruff, M., Structural Proteomics in Europe (SPINE)
Deposit date:2000-10-30
Release date:2002-02-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Overexpression, Purification, and Crystal Structure of Native ER alpha LBD
Protein Expr.Purif., 22, 2001
1G5Y
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1g5y
THE 2.0 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE RXRALPHA LIGAND BINDING DOMAIN TETRAMER IN THE PRESENCE OF A NON-ACTIVATING RETINOIC ACID ISOMER.
Descriptor:RETINOIC ACID RECEPTOR RXR-ALPHA
Authors:Gampe Jr., R.T., Montana, V.G., Lambert, M.H., Wisely, G.B., Milburn, M.V., Xu, H.E.
Deposit date:2000-11-02
Release date:2001-05-02
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix.
Genes Dev., 14, 2000
1GS4
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1gs4
STRUCTURAL BASIS FOR THE GLUCOCORTICOID RESPONSE IN A MUTANT HUMAN ANDROGEN RECEPTOR (ARCCR) DERIVED FROM AN ANDROGEN-INDEPENDENT PROSTATE CANCER
Descriptor:ANDROGEN RECEPTOR
Authors:Matias, P.M., Carrondo, M.A., Coelho, R., Thomaz, M., Zhao, X.-Y., Wegg, A., Crusius, K., Egner, U., Donner, P.
Deposit date:2001-12-27
Release date:2003-01-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for the Glucocorticoid Response in a Mutant Human Androgen Receptor (Ar(Ccr)) Derived from an Androgen-Independent Prostate Cancer
J.Med.Chem., 45, 2002
1GWQ
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1gwq
HUMAN OESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH RALOXIFENE CORE AND TIF2 NRBOX2 PEPTIDE
Descriptor:OESTROGEN RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 2
Authors:Pike, A.C.W., Brzozowski, A.M.
Deposit date:2002-03-22
Release date:2002-08-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor Alpha.
J.Biol.Chem., 277, 2002
1GWR
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1gwr
HUMAN OESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-OESTRADIOL AND TIF2 NRBOX3 PEPTIDE
Descriptor:OESTROGEN RECEPTOR, TRANSCRIPTION INTERMEDIARY FACTOR-2
Authors:Pike, A.C.W., Brzozowski, A.M.
Deposit date:2002-03-22
Release date:2002-08-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor Alpha.
J.Biol.Chem., 277, 2002
1GWX
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1gwx
MOLECULAR RECOGNITION OF FATTY ACIDS BY PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS
Descriptor:PPAR-DELTA PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS
Authors:Xu, H.E., Lambert, M.H., Montana, V.G., Park, D.J., Blanchard, S., Brown, P., Sternbach, D., Lehmann, J., Bruce, G.W., Willson, T.M., Kliewer, S.A., Milburn, M.V.
Deposit date:1999-03-17
Release date:2000-03-17
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular recognition of fatty acids by peroxisome proliferator-activated receptors.
Mol.Cell, 3, 1999
1H9U
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1h9u
THE STRUCTURE OF THE HUMAN RETINOID-X-RECEPTOR BETA LIGAND BINDING DOMAIN IN COMPLEX WITH THE SPECIFIC SYNTHETIC AGONIST LG100268
Descriptor:RETINOID X RECEPTOR, BETA
Authors:Schwabe, J.W.R., Love, J.D., Gooch, J.T.
Deposit date:2001-03-21
Release date:2002-04-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structural Basis for the Specificity of Retinoid-X Receptor-Selective Agonists: New Insights Into the Role of Helix H12
J.Biol.Chem., 277, 2002
1HG4
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1hg4
ULTRASPIRACLE LIGAND BINDING DOMAIN FROM DROSOPHILA MELANOGASTER
Descriptor:ULTRASPIRACLE
Authors:Schwabe, J.W.R., Clayton, G.M.
Deposit date:2000-12-12
Release date:2001-02-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the Ultraspiracle Ligand-Binding Domain Reveals a Nuclear Receptor Locked in an Inactive Conformation
Proc.Natl.Acad.Sci.USA, 98, 2001
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103354
entries available on 2014-09-17
00:00 UTC / 09:00 JST