PDB: 7 resultsInfo pagesStatus searchChemie searchBIRD

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2KYG	Structure of the AML1-ETO Nervy Domain - PKA(RIIa) complex and its contribution to AML1-ETO activity Descriptor: Protein CBFA2T1, cAMP-dependent protein kinase type II-alpha regulatory subunit Authors: Corpora, T.A, Cierpecki, T, Bushweller, J. Deposit date: 2010-05-25 Release date: 2010-10-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity. J.Mol.Biol., 402, 2010
2KNH	The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide Descriptor: Protein CBFA2T1, Transcription factor 12 Authors: Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H. Deposit date: 2009-08-25 Release date: 2009-10-06 Last modified: 2020-02-26 Method: SOLUTION NMR Cite: Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood, 113, 2009
4JOL	Complex structure of AML1-ETO NHR2 domain with HEB fragment Descriptor: Protein CBFA2T1, Transcription factor 12 Authors: Wang, Z, Patel, D.J. Deposit date: 2013-03-18 Release date: 2013-06-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.906 Å) Cite: A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature, 500, 2013
2H7B	Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO Descriptor: Core-binding factor, ML1-ETO Authors: Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M. Deposit date: 2006-06-01 Release date: 2006-07-11 Last modified: 2021-10-20 Method: SOLUTION NMR Cite: The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain Proc.Natl.Acad.Sci.USA, 103, 2006
1WQ6	The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity Descriptor: AML1-ETO Authors: Liu, Y, Cheney, M.D, Chruszcz, M, Lukasik, S.M, Hartman, K.L, Laue, T.M, Dauter, Z, Minor, W, Speck, N.A, Bushweller, J.H. Deposit date: 2004-09-23 Release date: 2005-10-04 Last modified: 2022-04-13 Method: X-RAY DIFFRACTION (2 Å) Cite: The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity Cancer Cell, 9, 2006
2ODD	Solution structure of the MYND domain from AML1-ETO complexed with SMRT, a corepressor Descriptor: Protein CBFA2T1, SMRT, ZINC ION Authors: Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H. Deposit date: 2006-12-22 Release date: 2007-06-19 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity. Cancer Cell, 11, 2007
2OD1	Solution structure of the MYND domain from human AML1-ETO Descriptor: Protein CBFA2T1, ZINC ION Authors: Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H. Deposit date: 2006-12-21 Release date: 2007-06-19 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity. Cancer Cell, 11, 2007