2H7B
Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO
Summary for 2H7B
| Entry DOI | 10.2210/pdb2h7b/pdb |
| NMR Information | BMRB: 7147 |
| Descriptor | Core-binding factor, ML1-ETO (1 entity in total) |
| Functional Keywords | 4 helix bundle, transcription |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 11887.72 |
| Authors | Plevin, M.J.,Zhang, J.,Guo, C.,Roeder, R.G.,Ikura, M. (deposition date: 2006-06-01, release date: 2006-07-11, Last modification date: 2021-10-20) |
| Primary citation | Plevin, M.J.,Zhang, J.,Guo, C.,Roeder, R.G.,Ikura, M. The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain Proc.Natl.Acad.Sci.USA, 103:10242-10247, 2006 Cited by PubMed: 16803958DOI: 10.1073/pnas.0603463103 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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