1WQ6
The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
Summary for 1WQ6
Entry DOI | 10.2210/pdb1wq6/pdb |
Descriptor | AML1-ETO (2 entities in total) |
Functional Keywords | nhr2, eto, aml1-eto, oncoprotein |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Potential): Q06455 |
Total number of polymer chains | 2 |
Total formula weight | 18307.46 |
Authors | Liu, Y.,Cheney, M.D.,Chruszcz, M.,Lukasik, S.M.,Hartman, K.L.,Laue, T.M.,Dauter, Z.,Minor, W.,Speck, N.A.,Bushweller, J.H. (deposition date: 2004-09-23, release date: 2005-10-04, Last modification date: 2022-04-13) |
Primary citation | Liu, Y.,Cheney, M.D.,Gaudet, J.J.,Chruszcz, M.,Lukasik, S.M.,Sugiyama, D.,Lary, J.,Cole, J.,Dauter, Z.,Minor, W.,Speck, N.A.,Bushweller, J.H. The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity Cancer Cell, 9:249-260, 2006 Cited by PubMed: 16616331DOI: 10.1016/j.ccr.2006.03.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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