PDB: 448 件ウェブページステータス検索Chemie searchBIRD

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4CCT	Dengue 1 cryo-EM reconstruction 分子名称: DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 M PROTEIN 著者 Kostyuchenko, V.A, Zhang, Q, Tan, J.L, Ng, T.S, Lok, S.M. 登録日 2013-10-28 公開日 2013-11-06 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process. J.Virol., 87, 2013
5AAW	Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency 分子名称: DENGUE SEROTYPE 4 ENVELOPE PROTEIN DOMAIN 3, SCFV513 著者 Wong, Y, Robinson, L, Lescar, J, Sasisekharan, R. 登録日 2015-07-30 公開日 2015-09-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope. Cell(Cambridge,Mass.), 162, 2015
4B03	6A Electron cryomicroscopy structure of immature Dengue virus serotype 1 分子名称: DENGUE VIRUS 1 E PROTEIN, DENGUE VIRUS 1 PRM PROTEIN 著者 Kostyuchenko, V.A, Zhang, Q, Tan, L.C, Ng, T.S, Lok, S.M. 登録日 2012-06-28 公開日 2013-06-05 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight Into the Maturation Process. J.Virol., 87, 2013
4C11	Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region 分子名称: DENGUE VIRUS TYPE 3 RNA DEPENDENT RNA POLYMERASE, ZINC ION 著者 Lim, S.P, Lescar, J. 登録日 2013-08-09 公開日 2013-08-21 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Crystal Structure of the Dengue Virus Ns5 Polymerase Delineates Inter-Domain Amino Acids Residues that Enhance its Thermostability and De Novo Initiation Activities. J.Biol.Chem., 288, 2013
2VBC	Crystal structure of the NS3 protease-helicase from Dengue virus 分子名称: DENGUE 4 NS3 FULL-LENGTH PROTEIN, PARTIAL POLYPROTEIN FOR NS2A AND NS2B, TYPE 4 PROTOTYPE DV4 H241 著者 Luo, D.H, Xu, T, Hunke, C, Gruber, G, Vasudevan, S.G, Lescar, J. 登録日 2007-09-10 公開日 2007-10-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Crystal Structure of the Ns3 Protease-Helicase from Dengue Virus. J.Virol., 82, 2008
6WY1	Crystal structure of an engineered thermostable dengue virus 2 envelope protein dimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dengue 2 soluble recombinant envelope 著者 Kudlacek, S.T, Lakshmanane, P, Kuhlman, B. 登録日 2020-05-12 公開日 2021-11-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies. Sci Adv, 7, 2021
4UIF	Cryo-EM structure of Dengue virus serotype 2 in complex with antigen-binding fragments of human antibody 2D22 分子名称: ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN PVP94 07 - ENVELOPE PROTEIN, ... 著者 Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.-N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Junior, J.E, Lok, S.-M. 登録日 2015-03-30 公開日 2015-07-15 最終更新日 2018-02-07 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
2BMF	Dengue virus RNA helicase at 2.4A 分子名称: RNA HELICASE 著者 Xu, T, Sampath, A, Chao, A, Wen, D, Nanao, M, Chene, P, Vasudevan, S.G, Lescar, J. 登録日 2005-03-14 公開日 2005-08-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A. J.Virol., 79, 2005
2BHR	Dengue virus RNA helicase 分子名称: RNA HELICASE, SULFATE ION 著者 Xu, T, Sampath, A, Chao, A, Wen, D, Nanao, M, Chene, P, Vasudevan, S.G, Lescar, J. 登録日 2005-01-17 公開日 2005-08-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A. J.Virol., 79, 2005
4M9F	Dengue virus NS2B-NS3 protease A125C variant at pH 8.5 分子名称: NS2B-NS3 protease 著者 Yildiz, M, Ghosh, S, Bell, J.A, Sherman, W, Hardy, J.A. 登録日 2013-08-14 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus. Acs Chem.Biol., 8, 2013
3UYP	Crystal structure of the dengue virus serotype 4 envelope protein domain III in complex with the variable domains of Mab 4E11 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Envelope protein, GLYCEROL, ... 著者 Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A. 登録日 2011-12-06 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody. Structure, 20, 2012
3UZE	Crystal structure of the dengue virus serotype 3 envelope protein domain III in complex with the variable domains of Mab 4E11 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Envelope protein, ... 著者 Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A. 登録日 2011-12-07 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody. Structure, 20, 2012
3UZQ	Crystal structure of the dengue virus serotype 1 envelope protein domain III in complex with the variable domains of Mab 4E11 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... 著者 Cockburn, J.J.B, Navarro Sanchez, M.E, Fretes, N, Urvoas, A, Staropoli, I, Kikuti, C.M, Coffey, L.L, Arenzana Seisdedos, F, Bedouelle, H, Rey, F.A. 登録日 2011-12-07 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mechanism of dengue virus broad cross-neutralization by a monoclonal antibody. Structure, 20, 2012
7DWT	Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 1 particle) 分子名称: Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein 著者 Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. 登録日 2021-01-18 公開日 2021-02-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (19 Å) 主引用文献 Antibody affinity versus dengue morphology influences neutralization. Plos Pathog., 17, 2021
7DWU	Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 2 particle) 分子名称: Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain, envelope protein 著者 Fibriansah, G, Ng, T.S, Kostyuchenko, V.A, Shi, J, Lok, S.M. 登録日 2021-01-18 公開日 2021-02-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (19 Å) 主引用文献 Antibody affinity versus dengue morphology influences neutralization. Plos Pathog., 17, 2021
5DTO	Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, MAGNESIUM ION, ... 著者 Zhao, Y, Soh, T.S, Lim, S.P, Chung, K.Y, Swaminathan, K, Vasudevan, S.G, Shi, P.-Y, Lescar, J, Luo, D. 登録日 2015-09-18 公開日 2015-11-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) Proc.Natl.Acad.Sci.USA, 112, 2015
5EHI	DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND MOLECULE BF287 分子名称: 4-[[3-[(2-azanyl-4-chloranyl-phenyl)carbamoylamino]phenyl]sulfonylamino]benzoic acid, NS5 methyltransferase dengue virus, S-ADENOSYLMETHIONINE 著者 Barral, K, Bricogne, G, Sharff, A. 登録日 2015-10-28 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.303 Å) 主引用文献 Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design. Eur.J.Med.Chem., 125, 2016
2J7U	Dengue virus NS5 RNA dependent RNA polymerase domain 分子名称: CHLORIDE ION, MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE, ... 著者 Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J. 登録日 2006-10-17 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution. J.Virol., 81, 2007
2J7W	Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP 分子名称: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-TRIPHOSPHATE, POLYPROTEIN, ... 著者 Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J. 登録日 2006-10-17 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution. J.Virol., 81, 2007
3J35	Cryo-EM reconstruction of Dengue virus at 37 C 分子名称: envelope protein 著者 Zhang, X.Z, Sheng, J, Plevka, P, Kuhn, R.J, Diamond, M.S, Rossmann, M.G. 登録日 2013-02-24 公開日 2013-04-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 Dengue structure differs at the temperatures of its human and mosquito hosts. Proc.Natl.Acad.Sci.USA, 110, 2013
6XD1	Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-640 分子名称: (2R)-4-(butyl{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}carbamoyl)-1-(2,2-diphenylpropanoyl)piperazine-2-carboxylic acid, RNA-dependent RNA polymerase, ZINC ION 著者 Arora, R, Benson, T.E, Liew, C.W, Lescar, J. 登録日 2020-06-09 公開日 2020-09-23 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. J.Virol., 94, 2020
6XD0	Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-434 分子名称: 2-[({2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)amino]-2,3-dihydro-1H-indene-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Arora, R, Benson, T.E, Liew, C.W, Lescar, J. 登録日 2020-06-09 公開日 2020-09-23 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (2.012 Å) 主引用文献 Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. J.Virol., 94, 2020
1UZG	CRYSTAL STRUCTURE OF THE DENGUE TYPE 3 VIRUS ENVELOPE PROTEIN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAJOR ENVELOPE PROTEIN E, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Modis, Y, Harrison, S.C. 登録日 2004-03-11 公開日 2005-03-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein J.Virol., 79, 2005
4UIH	Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. 分子名称: ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN 著者 Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M. 登録日 2015-03-30 公開日 2015-07-15 最終更新日 2018-02-07 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
5AAM	Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency 分子名称: ENVELOPE PROTEIN, SCFV513 著者 Wong, Y.H, Robinson, L.N, Lescar, J, Sasisekharan, R. 登録日 2015-07-27 公開日 2015-08-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope. Cell(Cambridge,Mass.), 162, 2015

 

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