5DTO

Dengue virus full length NS5 complexed with viral Cap 0-RNA and SAH

Summary for 5DTO

• Entry DOI: 10.2210/pdb5dto/pdb
• Related: 4V0Q 4V0R
• Descriptor: NS5, RNA (5'-R(P*AP*GP*UP*U)-3'), ZINC ION, ... (8 entities in total)
• Functional Keywords: dengue virus, nonstructural protein 5, 2'omtase, cap0 rna, innate immunity evasion, viral protein-rna complex, viral protein/rna
• Biological source: Dengue virus 3; More
• Total number of polymer chains: 2
• Total formula weight: 105153.54

Authors

Zhao, Y.,Soh, T.S.,Lim, S.P.,Chung, K.Y.,Swaminathan, K.,Vasudevan, S.G.,Shi, P.-Y.,Lescar, J.,Luo, D. (deposition date: 2015-09-18, release date: 2015-11-25, Last modification date: 2024-03-06)

• Primary citation: Zhao, Y.,Soh, T.S.,Lim, S.P.,Chung, K.Y.,Swaminathan, K.,Vasudevan, S.G.,Shi, P.-Y.,Lescar, J.,Luo, D.; Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5); Proc.Natl.Acad.Sci.USA, 112:14834-14839, 2015; PubMed: 26578813; DOI: 10.1073/pnas.1514978112

Experimental method

X-RAY DIFFRACTION (2.603 Å)