2J7W
Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP
Summary for 2J7W
Entry DOI | 10.2210/pdb2j7w/pdb |
Descriptor | POLYPROTEIN, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | nucleoside binding site, rna-dependent rna polymerase, dengue, flavivirus, high-throughput assay, viral protein |
Biological source | DENGUE VIRUS |
Cellular location | Envelope protein E: Virion membrane; Multi- pass membrane protein: Q6DLV0 |
Total number of polymer chains | 1 |
Total formula weight | 74356.93 |
Authors | Yap, T.L.,Xu, T.,Chen, Y.L.,Malet, H.,Egloff, M.P.,Canard, B.,Vasudevan, S.G.,Lescar, J. (deposition date: 2006-10-17, release date: 2007-03-13, Last modification date: 2023-12-13) |
Primary citation | Yap, T.L.,Xu, T.,Chen, Y.L.,Malet, H.,Egloff, M.P.,Canard, B.,Vasudevan, S.G.,Lescar, J. Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution. J.Virol., 81:4753-, 2007 Cited by PubMed: 17301146DOI: 10.1128/JVI.02283-06 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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