Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8BLQ
DownloadVisualize
BU of 8blq by Molmil
Cryo-EM structure of the CODV-IL13-RefAb triple complex
分子名称: CODV-Fab, heavy chain, light chain, ...
著者Fernandez-Martinez, D, Kandiah, E.
登録日2022-11-10
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM.
Sci Rep, 13, 2023
7REW
DownloadVisualize
BU of 7rew by Molmil
Crystal Structure of IL-13 in complex with MMAb3 Fab
分子名称: IL13, anti-cyno interleukin 13 Fab heavy chain, anti-cyno interleukin 13 Fab light chain
著者Sudom, A, Min, X.
登録日2021-07-13
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence-based affinity maturation.
J.Biol.Chem., 298, 2022
4I77
DownloadVisualize
BU of 4i77 by Molmil
Lebrikizumab Fab bound to IL-13
分子名称: Interleukin-13, Lebrikizumab heavy chain, Lebrikizumab light chain
著者Eigenbrot, C, Ultsch, M.
登録日2012-11-30
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Signaling Blockade by Anti-IL-13 Antibody Lebrikizumab.
J.Mol.Biol., 425, 2013
1GA3
DownloadVisualize
BU of 1ga3 by Molmil
NMR STRUCTURE OF INTERLEUKIN-13
分子名称: Interleukin-13
著者Eisenmesser, E.Z, Horita, D.A, Altieri, A.S, Byrd, R.A.
登録日2000-11-29
公開日2001-07-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of interleukin-13 and insights into receptor engagement
J.Mol.Biol., 310, 2001
4PS4
DownloadVisualize
BU of 4ps4 by Molmil
Crystal structure of the complex between IL-13 and M1295 FAB
分子名称: Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2014-03-06
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398, 2010
3L5X
DownloadVisualize
BU of 3l5x by Molmil
Crystal structure of the complex between IL-13 and H2L6 FAB
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, H2L6 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2009-12-22
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
3L5W
DownloadVisualize
BU of 3l5w by Molmil
Crystal structure of the complex between IL-13 and C836 FAB
分子名称: C836 HEAVY CHAIN, C836 LIGHT CHAIN, GLYCEROL, ...
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2009-12-22
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
5KNH
DownloadVisualize
BU of 5knh by Molmil
CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13
分子名称: ACETATE ION, DARPIN 6G9, IL13
著者Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G.
登録日2016-06-28
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
3G6D
DownloadVisualize
BU of 3g6d by Molmil
Crystal structure of the complex between CNTO607 Fab and IL-13
分子名称: CNTO607 Fab Heavy chain, CNTO607 Fab Light chain, Interleukin-13, ...
著者Teplyakov, A, Obmolova, G, Gilliland, G.L.
登録日2009-02-06
公開日2009-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607.
J.Mol.Biol., 389, 2009
5L6Y
DownloadVisualize
BU of 5l6y by Molmil
il13 in complex with tralokinumab
分子名称: FORMIC ACID, Interleukin-13, tralokinumab FAb digest VH, ...
著者Breed, J.
登録日2016-06-01
公開日2016-12-21
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R alpha 1 and IL-13R alpha 2.
J. Mol. Biol., 429, 2017
1IJZ
DownloadVisualize
BU of 1ijz by Molmil
Solution Structure of Human IL-13
分子名称: INTERLEUKIN-13
著者Moy, F.J, Diblasio, E, Wilhelm, J, Powers, R.
登録日2001-05-01
公開日2002-05-01
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of human IL-13 and implication for receptor binding.
J.Mol.Biol., 310, 2001
1IK0
DownloadVisualize
BU of 1ik0 by Molmil
Solution Structure of Human IL-13
分子名称: INTERLEUKIN-13
著者Moy, F.J, Diblasio, E, Wilhelm, J, Powers, R.
登録日2001-05-01
公開日2002-05-01
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of human IL-13 and implication for receptor binding.
J.Mol.Biol., 310, 2001
3BPO
DownloadVisualize
BU of 3bpo by Molmil
Crystal structure of the IL13-IL4R-IL13Ra ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 13, ...
著者Garcia, K.C.
登録日2007-12-18
公開日2008-02-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
5E4E
DownloadVisualize
BU of 5e4e by Molmil
Engineered Interleukin-13 bound to receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ...
著者Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C.
登録日2015-10-05
公開日2015-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci.Signal., 8, 2015
3LB6
DownloadVisualize
BU of 3lb6 by Molmil
The structure of IL-13 in complex with IL-13Ralpha2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Interleukin-13, ...
著者Lupardus, P.J, Garcia, K.C, Birnbaum, M.E.
登録日2010-01-07
公開日2010-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2.
Structure, 18, 2010

218853

件を2024-04-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon