5E4E
Engineered Interleukin-13 bound to receptor
Summary for 5E4E
Entry DOI | 10.2210/pdb5e4e/pdb |
Descriptor | Interleukin-13, Interleukin-4 receptor subunit alpha, Interleukin-13 receptor subunit alpha-1, ... (5 entities in total) |
Functional Keywords | agonist-receptor complex, protein engineering, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 73361.29 |
Authors | Moraga, I.,Thomas, C.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-10-05, release date: 2015-12-02, Last modification date: 2020-07-29) |
Primary citation | Moraga, I.,Richter, D.,Wilmes, S.,Winkelmann, H.,Jude, K.,Thomas, C.,Suhoski, M.M.,Engleman, E.G.,Piehler, J.,Garcia, K.C. Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Sci.Signal., 8:ra114-ra114, 2015 Cited by PubMed: 26554818DOI: 10.1126/scisignal.aab2677 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report