3G6D
| Crystal structure of the complex between CNTO607 Fab and IL-13 | 分子名称: | CNTO607 Fab Heavy chain, CNTO607 Fab Light chain, Interleukin-13, ... | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | 登録日 | 2009-02-06 | 公開日 | 2009-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607. J.Mol.Biol., 389, 2009
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7REW
| Crystal Structure of IL-13 in complex with MMAb3 Fab | 分子名称: | IL13, anti-cyno interleukin 13 Fab heavy chain, anti-cyno interleukin 13 Fab light chain | 著者 | Sudom, A, Min, X. | 登録日 | 2021-07-13 | 公開日 | 2022-05-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence-based affinity maturation. J.Biol.Chem., 298, 2022
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4I77
| Lebrikizumab Fab bound to IL-13 | 分子名称: | Interleukin-13, Lebrikizumab heavy chain, Lebrikizumab light chain | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2012-11-30 | 公開日 | 2013-02-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of Signaling Blockade by Anti-IL-13 Antibody Lebrikizumab. J.Mol.Biol., 425, 2013
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8BLQ
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4PS4
| Crystal structure of the complex between IL-13 and M1295 FAB | 分子名称: | Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | 登録日 | 2014-03-06 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody. J.Mol.Biol., 398, 2010
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1GA3
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1IJZ
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5KNH
| CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13 | 分子名称: | ACETATE ION, DARPIN 6G9, IL13 | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G. | 登録日 | 2016-06-28 | 公開日 | 2016-12-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Conformational flexibility of an anti-IL-13 DARPin. Protein Eng. Des. Sel., 30, 2017
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5L6Y
| il13 in complex with tralokinumab | 分子名称: | FORMIC ACID, Interleukin-13, tralokinumab FAb digest VH, ... | 著者 | Breed, J. | 登録日 | 2016-06-01 | 公開日 | 2016-12-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R alpha 1 and IL-13R alpha 2. J. Mol. Biol., 429, 2017
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1IK0
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3L5X
| Crystal structure of the complex between IL-13 and H2L6 FAB | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, H2L6 HEAVY CHAIN, ... | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | 登録日 | 2009-12-22 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Human framework adaptation of a mouse anti-human IL-13 antibody. J.Mol.Biol., 398, 2010
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3L5W
| Crystal structure of the complex between IL-13 and C836 FAB | 分子名称: | C836 HEAVY CHAIN, C836 LIGHT CHAIN, GLYCEROL, ... | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | 登録日 | 2009-12-22 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Human framework adaptation of a mouse anti-human IL-13 antibody. J.Mol.Biol., 398, 2010
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5E4E
| Engineered Interleukin-13 bound to receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ... | 著者 | Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C. | 登録日 | 2015-10-05 | 公開日 | 2015-12-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Sci.Signal., 8, 2015
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3BPO
| Crystal structure of the IL13-IL4R-IL13Ra ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 13, ... | 著者 | Garcia, K.C. | 登録日 | 2007-12-18 | 公開日 | 2008-02-05 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System. Cell(Cambridge,Mass.), 132, 2008
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3LB6
| The structure of IL-13 in complex with IL-13Ralpha2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Interleukin-13, ... | 著者 | Lupardus, P.J, Garcia, K.C, Birnbaum, M.E. | 登録日 | 2010-01-07 | 公開日 | 2010-03-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2. Structure, 18, 2010
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