4R6U
| IL-18 receptor complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-18, Interleukin-18 receptor 1 | 著者 | Wei, H, Wang, X. | 登録日 | 2014-08-26 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for the specific recognition of IL-18 by its alpha receptor. Febs Lett., 588, 2014
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8C3U
| Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist | 分子名称: | (S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid, Interleukin-1 beta | 著者 | Rondeau, J.-M, Lehmann, S, Koch, E. | 登録日 | 2022-12-28 | 公開日 | 2023-09-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | 主引用文献 | Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1 beta. Nat Commun, 14, 2023
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21BI
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5UC6
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7I1B
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5MVZ
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8I1B
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7Z4T
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1S0L
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2MIB
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6NCU
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5BOW
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6HPI
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31BI
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6Y8I
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5HN1
| Crystal structure of Interleukin-37 | 分子名称: | Interleukin-37, SULFATE ION | 著者 | Ellisdon, A.M, Nold-Petry, C.A, Nold, M.F, Whisstock, J.C. | 登録日 | 2016-01-17 | 公開日 | 2017-02-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Homodimerization attenuates the anti-inflammatory activity of interleukin-37. Sci Immunol, 2, 2017
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6Y8M
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5BVP
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2VXT
| Crystal structure of human IL-18 complexed to murine reference antibody 125-2H Fab | 分子名称: | CHLORIDE ION, INTERLEUKIN-18, MAGNESIUM ION, ... | 著者 | Argiriadi, M.A, Xiang, T, Wu, C, Ghayur, T, Borhani, D.W. | 登録日 | 2008-07-10 | 公開日 | 2009-06-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18. J.Biol.Chem., 284, 2009
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6I1B
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5I1B
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2WRY
| Crystal structure of chicken cytokine interleukin 1 beta | 分子名称: | INTERLEUKIN-1BETA | 著者 | Lu, W.S, Cheng, C.S, Lyu, P.C, Lee, L.H, Wang, W.C, Yin, H.S. | 登録日 | 2009-09-03 | 公開日 | 2010-09-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Structural and Functional Comparison of Cytokine Interleukin-1 Beta from Chicken and Human. Mol.Immunol., 48, 2011
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6P9E
| Crystal structure of IL-36gamma complexed to A-552 | 分子名称: | (2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic acid, Interleukin-36 gamma | 著者 | Argiriadi, M.A, Todorovic, T, Su, Z, Putman, B, Kakavas, S.J, Salte, K.M, McDonald, H.A, Wetter, J.B, Paulsboe, S.E, Sun, Q, Gerstein, C.E, Medina, L, Sielaff, B, Sadhukhan, R, Stockmann, H, Richardson, P.L, Qiu, W, Henry, R.F, Herold, J.M, Shotwell, J.B, McGaraughty, S.P, Honore, P, Gopalakrishnan, S.M, Sun, C.C, Scott, V.E. | 登録日 | 2019-06-10 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Small Molecule IL-36 gamma Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis. Sci Rep, 9, 2019
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2NVH
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8RYS
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