PDB: 617 件ウェブページステータス検索Chemie searchBIRD

---

8R0Z	14-3-3 sigma in complex with TAZ peptide and stabilizing fragment TCF199 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, WW domain-containing transcription regulator protein 1, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2023-11-01 公開日 2024-09-04 最終更新日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Fragment-Based Interrogation of the 14-3-3/TAZ Protein-Protein Interaction. Biochemistry, 63, 2024
5WXN	Structure of the LKB1 and 14-3-3 complex 分子名称: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase STK11 著者 Ding, S, Shi, Z.B. 登録日 2017-01-08 公開日 2017-04-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Structure of the complex of phosphorylated liver kinase B1 and 14-3-3 zeta Acta Crystallogr F Struct Biol Commun, 73, 2017
1QJA	14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2) 分子名称: 14-3-3 PROTEIN ZETA, PHOSPHOPEPTIDE 著者 Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B. 登録日 1999-06-23 公開日 1999-09-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding Mol.Cell, 4, 1999
7EXE	Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide 分子名称: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22 著者 Yan, L, Okatsu, K, Fukai, S. 登録日 2021-05-27 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice Cell Rep, 2021
5MHC	Crystal structure of 14-3-3sigma and a p53 C-terminal 12-mer synthetic phosphopeptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, LYS-LEU-MET-PHE-LYS-TPO-GLU-GLY-PRO-ASP-SER-ASP, ... 著者 Andrei, S, Ottmann, C, Leysen, S. 登録日 2016-11-24 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction. FEBS Lett., 591, 2017
4QLI	A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation 分子名称: 14-3-3 protein sigma, GLYCEROL, MAGNESIUM ION, ... 著者 Bier, D, Ottmann, C. 登録日 2014-06-12 公開日 2015-06-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation To be Published
4WRQ	Crystal Structure of 14-3-3 zeta with Chibby peptide 分子名称: 14-3-3 protein zeta/delta, Chibby 著者 Killoran, R.C, Shilton, B.H, Choy, W.Y. 登録日 2014-10-24 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.409 Å) 主引用文献 Structural Analysis of the 14-3-3 zeta /Chibby Interaction Involved in Wnt/ beta-Catenin Signaling. Plos One, 10, 2015
8HEW	Potato 14-3-3 St14f 分子名称: 14-3-3 protein, StFDL1 peptide 著者 Taoka, K, Kawahara, I, Shinya, S, Harada, K, Muranaka, T, Furuita, K, Nakagawa, A, Fujiwara, T, Tsuji, H, Kojima, C. 登録日 2022-11-08 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening. Plant J., 112, 2022
4BG6	14-3-3 interaction with Rnd3 prenyl-phosphorylation motif 分子名称: 14-3-3 PROTEIN ZETA/DELTA, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, FARNESYL, ... 著者 Riou, P, Kjaer, S, Purkiss, A, O'Reilly, N, McDonald, N.Q. 登録日 2013-03-23 公開日 2013-05-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins. Cell(Cambridge,Mass.), 153, 2013
4Y3B	Crystal structure of C-terminal modified Tau peptide-hybrid 201D with 14-3-3sigma 分子名称: (2S)-2-(2-methoxyethyl)pyrrolidine, 14-3-3 protein sigma, ARG-THR-PRO-SEP-LEU-PRO-THR-[H][C@@]1(C(C2=CC=CC=C2)C3=CC=CC=C3)CCCN1C 著者 Bartel, M, Milroy, L.G, Brunsveld, L, Ottmann, C. 登録日 2015-02-10 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
7V9B	Crystal Structure of 14-3-3 epsilon with FOXO3a peptide 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, ARG-ARG-ARG-ALA-VAL-SEP-MET-ASP-ASN-SER-ASN, ... 著者 Mathivanan, S, Kamariah, N. 登録日 2021-08-24 公開日 2022-08-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of a 14-3-3 epsilon :FOXO3a pS253 Phosphopeptide Complex Reveals 14-3-3 Isoform-Specific Binding of Forkhead Box Class O Transcription Factor (FOXO) Phosphoproteins. Acs Omega, 7, 2022
8EQ8	The crystal structure of 14-3-3 Beta containing 3-nitrotyrosine at position Y130 分子名称: 14-3-3 protein beta/alpha 著者 Zhu, P, Cooley, R.B. 登録日 2022-10-07 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation. Protein Sci., 32, 2023
4Y32	Crystal structure of C-terminal modified Tau peptide-hybrid 109B with 14-3-3sigma 分子名称: (2S)-2-(2-methoxyethyl)pyrrolidine, 14-3-3 protein sigma, ARG-THR-PRO-SEP-LEU-PRO-CNC(C(C)O)C(=O)N1CCCC1CCOC 著者 Bartel, M, Milroy, L, Bier, D, Brunsveld, L, Ottmann, C. 登録日 2015-02-10 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
8EQH	The crystal structure of 14-3-3 Beta containing 3-nitrotyrosine at position Y213 分子名称: 14-3-3 protein beta/alpha 著者 Zhu, P, Cooley, R.B. 登録日 2022-10-07 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation. Protein Sci., 32, 2023
6NV2	14-3-3 sigma with RelA/p65 binding site pS45 in complex with DP005 分子名称: (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2019-02-04 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products. J.Am.Chem.Soc., 142, 2020
5HF3	Crystal structure of C-terminal modified Tau peptide-hybrid 201D with 14-3-3sigma 分子名称: 14-3-3 protein sigma, modified Tau peptide 著者 Bartel, M, Milroy, L.G, Brunsveld, L, Ottmann, C. 登録日 2016-01-06 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Stabilizer-Guided Inhibition of Protein-Protein Interactions. Angew.Chem.Int.Ed.Engl., 54, 2015
6KZH	14-3-3 protein in Complex with CIC S173 phosphorylated peptide 分子名称: 14-3-3 protein theta, CIC pS173 peptide 著者 Wen, Y, Shao, Y. 登録日 2019-09-24 公開日 2020-09-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.645 Å) 主引用文献 14-3-3 protein in Complex with CIC S173 phosphorylated peptide To Be Published
2V7D	14-3-3 protein zeta in complex with Thr758 phosphorylated integrin beta2 peptide 分子名称: 14-3-3 PROTEIN ZETA/DELTA, INTEGRIN BETA CHAIN, BETA 2 VARIANT 著者 Takala, H, Ylanne, J. 登録日 2007-07-30 公開日 2008-06-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding. Blood, 112, 2008
6KZG	14-3-3 protein in Complex with CIC S301 phosphorylated peptide 分子名称: 14-3-3 protein theta, ARG-SER-MET-SER-GLU-THR-GLY-THR 著者 Wen, Y, Shao, Y. 登録日 2019-09-24 公開日 2020-09-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 14-3-3 protein in Complex with CIC S301 phosphorylated peptide To Be Published
1YWT	Crystal structure of the human sigma isoform of 14-3-3 in complex with a mode-1 phosphopeptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, synthetic optimal phosphopeptide (mode-1) 著者 Wilker, E.W, Grant, R.A, Artim, S.C, Yaffe, M.B. 登録日 2005-02-18 公開日 2005-03-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A structural basis for 14-3-3sigma functional specificity. J.Biol.Chem., 280, 2005
5IQP	14-3-3 PROTEIN TAU ISOFORM 分子名称: 14-3-3 protein theta, SULFATE ION 著者 Xiao, B, Smerdon, S.J, Gamblin, S.J. 登録日 2016-03-11 公開日 2016-03-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways Nature, 376, 1995
7XBQ	Crystal structure of potato 14-3-3 protein St14f 分子名称: Putative 14-3-3 protein 著者 Harada, K, Kojima, C, Yamashita, E, Nakagawa, A. 登録日 2022-03-21 公開日 2022-07-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of potato 14-3-3 protein St14f revealed the importance of helix I in StFDL1 recognition. Sci Rep, 12, 2022
2WH0	Recognition of an intrachain tandem 14-3-3 binding site within protein kinase C epsilon 分子名称: 14-3-3 PROTEIN ZETA/DELTA, CALCIUM ION, PROTEIN KINASE C EPSILON TYPE, ... 著者 Kostelecky, B, Saurin, A.T, Purkiss, A, Parker, P.J, McDonald, N.Q. 登録日 2009-04-28 公開日 2009-08-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Recognition of an Intra-Chain Tandem 14-3-3 Binding Site within Pkc Epsilon. Embo Rep., 10, 2009
1YZ5	The crystal structure of 14-3-3-sigma at 2.8 angstrom resolution 分子名称: 14-3-3 protein sigma 著者 Benzinger, A, Popowicz, G.M, Holak, T.A, Hermeking, H. 登録日 2005-02-28 公開日 2005-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization. Cell Res., 15, 2005
1A38	14-3-3 PROTEIN ZETA BOUND TO R18 PEPTIDE 分子名称: 14-3-3 PROTEIN ZETA, R18 PEPTIDE (PHCVPRDLSWLDLEANMCLP) 著者 Petosa, C, Masters, S.C, Pohl, J, Wang, B, Fu, H, Liddington, R.C. 登録日 1998-01-28 公開日 1999-03-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. J.Biol.Chem., 273, 1998

 

12345678910111213141516>