4QLI
A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation
Summary for 4QLI
Entry DOI | 10.2210/pdb4qli/pdb |
Related | 4IEA 4JDD 4N7G |
Descriptor | 14-3-3 protein sigma, Zinc finger protein SNAI1, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | 14-3-3, adapter protein, protein-protein interaction, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P31947 Nucleus: O95863 |
Total number of polymer chains | 2 |
Total formula weight | 27420.41 |
Authors | |
Primary citation | Liu, Y.,Prokop, J.W.,Peng, H.,Karar, J.,White, D.,Hou, Z.,Qin, Y.S.,Bier, D.,Ottmann, C.,Waxman, S.,Halazonetis, T.D.,Rauscher III, F.J. A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation To be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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