1AWE
 
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5C79
 | | PH domain of ASAP1 in complex with diC4-PtdIns(4,5)P2 | | 分子名称: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, Arf-GAP, CHLORIDE ION | | 著者 | Xia, D, Tang, W.K. | | 登録日 | 2015-06-24 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
Structure, 23, 2015
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7MYX
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5C6R
 | | Crystal structure of PH domain of ASAP1 | | 分子名称: | Arf-GAP, PHOSPHATE ION, TRIETHYLENE GLYCOL | | 著者 | Xia, D, Tang, W.K. | | 登録日 | 2015-06-23 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
Structure, 23, 2015
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5MR1
 | | Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1) | | 分子名称: | Interactor protein for cytohesin exchange factors 1 | | 著者 | Newman, J.A, Aitkenhead, H, Wang, D, Burgess-Brown, N, Williams, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2016-12-21 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1)
To be published
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1H10
 | | HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE | | 分子名称: | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-ALPHA SERINE/THREONINE KINASE | | 著者 | Thomas, C.C, Deak, M, Alessi, D.R, Van Aalten, D.M.F. | | 登録日 | 2002-07-01 | | 公開日 | 2003-06-27 | | 最終更新日 | 2019-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
Curr.Biol., 12, 2002
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7VS3
 | | The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH | | 分子名称: | Calcium-dependent secretion activator 1, SULFATE ION | | 著者 | Zhou, H, Wei, Z.Q, Zhang, L, Ren, Y.J, Ma, C. | | 登録日 | 2021-10-25 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | | 主引用文献 | The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis.
Structure, 31, 2023
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1BAK
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7YIS
 | | Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate | | 分子名称: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 | | 著者 | Zhang, Y.J, Liu, Y.R, Wu, B. | | 登録日 | 2022-07-18 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
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7YIR
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2I5F
 | | Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,5,6)P5 | | 分子名称: | (1R,2R,3R,4R,5S,6S)-6-HYDROXYCYCLOHEXANE-1,2,3,4,5-PENTAYL PENTAKIS[DIHYDROGEN (PHOSPHATE)], Pleckstrin | | 著者 | Jackson, S.G, Haslam, R.J, Junop, M.S. | | 登録日 | 2006-08-24 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate.
Bmc Struct.Biol., 7, 2007
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2I5C
 | | Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,4,5)P5 | | 分子名称: | (1R,2S,3R,4S,5S,6R)-6-HYDROXYCYCLOHEXANE-1,2,3,4,5-PENTAYL PENTAKIS[DIHYDROGEN (PHOSPHATE)], Pleckstrin | | 著者 | Jackson, S.G, Haslam, R.J, Junop, M.S. | | 登録日 | 2006-08-24 | | 公開日 | 2007-08-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate.
Bmc Struct.Biol., 7, 2007
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2KCJ
 | | solution structure of FAPP1 PH domain | | 分子名称: | Pleckstrin homology domain-containing family A member 3 | | 著者 | Lenoir, M, Coskun, U, James, J, Simons, K, Overduin, M. | | 登録日 | 2008-12-22 | | 公開日 | 2009-12-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains.
Embo Rep., 11, 2010
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7KJZ
 | | crystal structure of PLEKHA7 PH domain biding inositol-tetraphosphate | | 分子名称: | 1,2-ETHANEDIOL, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Pleckstrin homology domain-containing family A member 7 | | 著者 | Marassi, F.M, Aleshin, A.E, Liddington, R.C. | | 登録日 | 2020-10-26 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
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7KK7
 | | crystal structure of ligand-free PLEKHA7 PH domain | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Pleckstrin homology domain-containing family A member 7 | | 著者 | Marassi, F.M, Aleshin, A.E, Liddington, R.C. | | 登録日 | 2020-10-27 | | 公開日 | 2021-04-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
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7KJO
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6BNM
 | | Crystal Structure of the P-Rex2 PH domain | | 分子名称: | CHLORIDE ION, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein | | 著者 | Cash, J.N, Sharma, P.V, Tesmer, J.J.G. | | 登録日 | 2017-11-17 | | 公開日 | 2018-11-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and biochemical characterization of the pleckstrin homology domain of the RhoGEF P-Rex2 and its regulation by PIP3.
J.Struct.Biol., 1, 2019
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6F24
 | | PH domain from PfAPH | | 分子名称: | C-terminal PH domain from PfAPH | | 著者 | Darvill, N, Liu, B, Matthews, S, Soldati-Favre, D, Rouse, S, Benjamin, S, Blake, T, Dubois, D.J, Hammoudi, P.M, Pino, P. | | 登録日 | 2017-11-23 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | C-terminal PH domain from P. falciparum acylated plekstrin homology domain containing protein (APH)
To Be Published
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1P6S
 | | Solution Structure of the Pleckstrin Homology Domain of Human Protein Kinase B beta (Pkb/Akt) | | 分子名称: | RAC-beta serine/threonine protein kinase | | 著者 | Auguin, D, Barthe, P, Auge-Senegas, M.T, Stern, M.H, Noguchi, M, Roumestand, C. | | 登録日 | 2003-04-30 | | 公開日 | 2004-05-18 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and backbone dynamics of the pleckstrin homology domain of the human
protein kinase B (PKB/Akt). Interaction with inositol phosphates.
J.BIOMOL.NMR, 28, 2004
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1PLS
 | | SOLUTION STRUCTURE OF A PLECKSTRIN HOMOLOGY DOMAIN | | 分子名称: | PLECKSTRIN HOMOLOGY DOMAIN | | 著者 | Yoon, H.S, Hajduk, P.J, Petros, A.M, Olejniczak, E.T, Meadows, R.P, Fesik, S.W. | | 登録日 | 1994-05-03 | | 公開日 | 1995-06-03 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a pleckstrin-homology domain.
Nature, 369, 1994
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1PMS
 | | PLECKSTRIN HOMOLOGY DOMAIN OF SON OF SEVENLESS 1 (SOS1) WITH GLYCINE-SERINE ADDED TO THE N-TERMINUS, NMR, 20 STRUCTURES | | 分子名称: | SOS 1 | | 著者 | Koshiba, S, Kigawa, T, Kim, J, Shirouzu, M, Bowtell, D, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1997-02-18 | | 公開日 | 1997-05-15 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1).
J.Mol.Biol., 269, 1997
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5U78
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5U77
 | | Crystal structure of ORP8 PH domain | | 分子名称: | FORMIC ACID, N-(2-hydroxyethyl)-N,N-dimethyl-3-sulfopropan-1-aminium, Oxysterol-binding protein-related protein 8 | | 著者 | Ghai, R, Yang, H. | | 登録日 | 2016-12-11 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.157 Å) | | 主引用文献 | ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.
Nat Commun, 8, 2017
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3NSU
 | | A Systematic Screen for Protein-Lipid Interactions in Saccharomyces cerevisiae | | 分子名称: | Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1, SULFATE ION | | 著者 | Gallego, O, Fernandez-Tornero, C, Aguilar-Gurrieri, C, Muller, C, Gavin, A.C. | | 登録日 | 2010-07-02 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae.
Mol. Syst. Biol., 6, 2010
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3PP2
 | | Crystal structure of the pleckstrin homology domain of ArhGAP27 | | 分子名称: | CITRIC ACID, GLYCEROL, Rho GTPase-activating protein 27, ... | | 著者 | Shen, L, Tempel, W, Tong, Y, Nedyalkova, L, Li, Y, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-23 | | 公開日 | 2010-12-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.421 Å) | | 主引用文献 | Crystal structure of the pleckstrin homology domain of ArhGAP27
to be published
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