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7VS3

The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH

Summary for 7VS3
Entry DOI10.2210/pdb7vs3/pdb
DescriptorCalcium-dependent secretion activator 1, SULFATE ION (3 entities in total)
Functional Keywordsca2+-dependent exocytosis; vesicle priming; munc13; caps; snare complex assembly, exocytosis
Biological sourceRattus norvegicus (Rat)
Total number of polymer chains1
Total formula weight27973.81
Authors
Zhou, H.,Wei, Z.Q.,Zhang, L.,Ren, Y.J.,Ma, C. (deposition date: 2021-10-25, release date: 2023-02-15, Last modification date: 2023-11-29)
Primary citationZhang, L.,Li, L.,Wei, Z.,Zhou, H.,Liu, H.,Wang, S.,Ren, Y.,Dai, T.,Wang, J.,Hu, Z.,Ma, C.
The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis.
Structure, 31:424-, 2023
Cited by
PubMed: 36863339
DOI: 10.1016/j.str.2023.02.004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.595 Å)
Structure validation

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