7MYX

Crystal structure of the PH domain (R86A) of Akt1

Summary for 7MYX

Entry DOI	10.2210/pdb7myx/pdb
Descriptor	RAC-alpha serine/threonine-protein kinase (2 entities in total)
Functional Keywords	kinase, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	14456.34
Authors	Bae, H.,Park, E.,Cole, P.A.,Eck, M.J. (deposition date: 2021-05-22, release date: 2022-11-09, Last modification date: 2023-10-18)
Primary citation	Bae, H.,Viennet, T.,Park, E.,Chu, N.,Salguero, A.,Eck, M.J.,Arthanari, H.,Cole, P.A. PH domain-mediated autoinhibition and oncogenic activation of Akt. Elife, 11:-, 2022 Cited by PubMed: 35968932 DOI: 10.7554/eLife.80148 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.39 Å)

Structure validation