4XCR
| Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Logan, D.T, Danielsson, J, Mu, X, Binolfi, A, Theillet, F, Bekei, B, Lang, L, Wennerstrom, H, Selenko, P, Oliveberg, M. | 登録日 | 2014-12-18 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.602 Å) | 主引用文献 | Thermodynamics of protein destabilization in live cells. Proc. Natl. Acad. Sci. U.S.A., 112, 2015
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2K4W
| The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica | 分子名称: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Mori, M, Jimenez, B, Piccioli, M, Battistoni, A, Sette, M, Structural Proteomics in Europe (SPINE) | 登録日 | 2008-06-20 | 公開日 | 2008-11-18 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica: Structural Insights To Understand the Evolution toward the Dimeric Structure. Biochemistry, 47, 2008
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8CCX
| Human SOD1 in complex with S-XL6 cross-linker | 分子名称: | COPPER (II) ION, DIMETHYL SULFOXIDE, SULFATE ION, ... | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | 登録日 | 2023-01-27 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS. Plos Biol., 22, 2024
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4MCM
| Human SOD1 C57S Mutant, As-isolated | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | 著者 | Sea, K, Sohn, S.H, Durazo, A, Sheng, Y, Shaw, B, Cao, X, Taylor, A.B, Whitson, L.J, Holloway, S.P, Hart, P.J, Cabelli, D.E, Gralla, E.B, Valentine, J.S. | 登録日 | 2013-08-21 | 公開日 | 2014-08-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase. J.Biol.Chem., 290, 2015
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7NXX
| Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | 著者 | Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C. | 登録日 | 2021-03-19 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | 主引用文献 | Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1 To Be Published
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5CU9
| CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO | 分子名称: | Cell surface Cu-only superoxide dismutase 5, SULFATE ION | 著者 | Waninger-Saroni, J.J, Taylor, A.B, Hart, P.J, Galaleldeen, A. | 登録日 | 2015-07-24 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | CANDIDA ALBICANS SUPEROXIDE DISMUTASE 5 (SOD5), APO To Be Published
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8GSQ
| Structure based studies reveal an atypical antipsychotic drug candidate - Paliperidone as a potent hSOD1 modulator with implications in ALS treatment. | 分子名称: | (9~{R})-3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-9-oxidanyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one, GLYCEROL, Superoxide dismutase [Cu-Zn], ... | 著者 | Aouti, S, Padmanabhan, B. | 登録日 | 2022-09-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based discovery of an antipsychotic drug, paliperidone, as a modulator of human superoxide dismutase 1: a potential therapeutic target in amyotrophic lateral sclerosis. Acta Crystallogr D Struct Biol, 79, 2023
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5IN2
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4FF9
| Crystal Structure of cysteinylated WT SOD1. | 分子名称: | COPPER (II) ION, CYSTEINE, Superoxide dismutase [Cu-Zn], ... | 著者 | Auclair, J.R, Brodkin, H.R, D'Aquino, J.A, Ringe, D, Petsko, G.A, Agar, J.N. | 登録日 | 2012-05-31 | 公開日 | 2013-09-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5003 Å) | 主引用文献 | Structural consequences of cysteinylation of cu/zn-superoxide dismutase. Biochemistry, 52, 2013
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4L05
| Cu/Zn superoxide dismutase from Brucella abortus | 分子名称: | COPPER (I) ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Shin, D.S, Didonato, M, Pratt, A.J, Bruns, C.K, Cabelli, D.E, Kroll, J.S, Belzer, C.A, Tabatabai, L.B, Tainer, J.A, Getzoff, E.D. | 登録日 | 2013-05-30 | 公開日 | 2013-10-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.098 Å) | 主引用文献 | Structural, Functional, and Immunogenic Insights on Cu,Zn Superoxide Dismutase Pathogenic Virulence Factors from Neisseria meningitidis and Brucella abortus. J.Bacteriol., 197, 2015
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2WZ0
| L38V SOD1 mutant complexed with aniline. | 分子名称: | 2-METHOXY-5-METHYLANILINE, COPPER (II) ION, D-SERINE, ... | 著者 | Antonyuk, S, Strange, R.W, Hasnain, S.S. | 登録日 | 2009-11-20 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization. J.Med.Chem., 53, 2010
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2XJL
| Monomeric Human Cu,Zn Superoxide dismutase without Cu ligands | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | 著者 | Saraboji, K, Leinartaite, L, Nordlund, A, Oliveberg, M, Logan, D.T. | 登録日 | 2010-07-07 | 公開日 | 2010-09-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the Als-Associated Enzyme Cu/Zn Superoxide Dismutase 1. J.Am.Chem.Soc., 132, 2010
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7YPP
| Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. | 分子名称: | CALCIUM ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Sim, K.-S, Fukuda, Y, Inoue, T. | 登録日 | 2022-08-04 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. Acta Crystallogr.,Sect.F, 79, 2023
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7B4O
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7YPR
| Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. | 分子名称: | COPPER (II) ION, POTASSIUM ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Sim, K.-S, Fukuda, Y, Inoue, T. | 登録日 | 2022-08-04 | 公開日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. Acta Crystallogr.,Sect.F, 79, 2023
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7B4P
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7FB6
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7FB9
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6DTK
| Heterodimers of FALS mutant SOD enzyme | 分子名称: | COPPER (II) ION, MALONATE ION, Superoxide dismutase C111S/D83S-C111S HETERODIMER, ... | 著者 | Streltsov, V.A, Nuttall, S.D, Ganio, K.E, Roberts, B. | 登録日 | 2018-06-17 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural characterization of heterodimers of FALS mutant SOD enzyme To Be Published
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5O40
| SOD1 bound to Ebselen | 分子名称: | N-phenyl-2-selanylbenzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | 著者 | Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. | 登録日 | 2017-05-25 | 公開日 | 2018-06-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nat Commun, 9, 2018
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7CJV
| Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a dilute environment | 分子名称: | Monomeric Human Cu,Zn Superoxide dismutase | 著者 | Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K. | 登録日 | 2020-07-14 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel. J.Phys.Chem.B, 125, 2021
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5O3Y
| SOD1 bound to Ebsulfur | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | 著者 | Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S. | 登録日 | 2017-05-25 | 公開日 | 2018-06-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nat Commun, 9, 2018
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4RVP
| Crystal structure of superoxide dismutase from sedum alfredii | 分子名称: | ZINC ION, superoxide dismutase | 著者 | Qiu, R, Li, C, Zhai, J, Tang, L, Zhang, H, Yuan, M, Hu, X. | 登録日 | 2014-11-27 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The positive effects of Cd and Cd-Zn relationship in the
Zn-related physiological processes involved in growth in the Zn/Cd hyperaccumulator Sedum alfredii To be Published
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8YD3
| Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol | 分子名称: | (2S)-decane-1,2,10-triol, GLYCEROL, Superoxide dismutase [Cu-Zn], ... | 著者 | Aouti, S, Padmanabhan, B. | 登録日 | 2024-02-19 | 公開日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal structure of human Cu-Zn Superoxide Dismutase 1 in complex with 1,2,10-Decanetriol To Be Published
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7CJW
| Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment | 分子名称: | Monomeric Human Cu,Zn Superoxide dismutase | 著者 | Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K. | 登録日 | 2020-07-14 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel. J.Phys.Chem.B, 125, 2021
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