4MCM

Human SOD1 C57S Mutant, As-isolated

Summary for 4MCM

• Entry DOI: 10.2210/pdb4mcm/pdb
• Related: 4MCN
• Descriptor: Superoxide dismutase [Cu-Zn], ZINC ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: oxidoreductase, human cu, zn superoxide dismutase, antioxidant, metal-binding, amyotrophic lateral sclerosis, disulfide bond
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00441
• Total number of polymer chains: 12
• Total formula weight: 192652.65

Authors

Sea, K.,Sohn, S.H.,Durazo, A.,Sheng, Y.,Shaw, B.,Cao, X.,Taylor, A.B.,Whitson, L.J.,Holloway, S.P.,Hart, P.J.,Cabelli, D.E.,Gralla, E.B.,Valentine, J.S. (deposition date: 2013-08-21, release date: 2014-08-27, Last modification date: 2023-09-20)

• Primary citation: Sea, K.,Sohn, S.H.,Durazo, A.,Sheng, Y.,Shaw, B.F.,Cao, X.,Taylor, A.B.,Whitson, L.J.,Holloway, S.P.,Hart, P.J.,Cabelli, D.E.,Gralla, E.B.,Valentine, J.S.; Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.; J.Biol.Chem., 290:2405-2418, 2015; PubMed: 25433341; DOI: 10.1074/jbc.M114.588798

Experimental method

X-RAY DIFFRACTION (2.2 Å)