5O40

SOD1 bound to Ebselen

Summary for 5O40

• Entry DOI: 10.2210/pdb5o40/pdb
• Descriptor: Superoxide dismutase [Cu-Zn], ZINC ION, N-phenyl-2-selanylbenzamide, ... (5 entities in total)
• Functional Keywords: oxidoreductase, complex, inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 32661.27

Authors

Capper, M.J.,Wright, G.S.A.,Antonyuk, S.V.,Hasnain, S.S. (deposition date: 2017-05-25, release date: 2018-06-13, Last modification date: 2024-02-07)

• Primary citation: Capper, M.J.,Wright, G.S.A.,Barbieri, L.,Luchinat, E.,Mercatelli, E.,McAlary, L.,Yerbury, J.J.,O'Neill, P.M.,Antonyuk, S.V.,Banci, L.,Hasnain, S.S.; The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.; Nat Commun, 9:1693-1693, 2018; PubMed: 29703933; DOI: 10.1038/s41467-018-04114-x

Experimental method

X-RAY DIFFRACTION (1.5 Å)