6UKW
 
 | | STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 10 | | Descriptor: | 4-[6-(3-{[2-(3-carboxypropanoyl)-4-fluoro-6-methoxy-1-benzothiophen-5-yl]oxy}propoxy)-5-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain | | Authors: | Lesburg, C.A. | | Deposit date: | 2019-10-06 | | Release date: | 2020-08-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | An orally available non-nucleotide STING agonist with antitumor activity.
Science, 369, 2020
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6UKY
 | | STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 12 | | Descriptor: | 4-(6-{3-[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-4-yl]propyl}-5-methoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain | | Authors: | Lesburg, C.A. | | Deposit date: | 2019-10-06 | | Release date: | 2020-08-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | An orally available non-nucleotide STING agonist with antitumor activity.
Science, 369, 2020
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6VEL
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8UZH
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2PE6
 | | Non-covalent complex between human SUMO-1 and human Ubc9 | | Descriptor: | SUMO-conjugating enzyme UBC9, Small ubiquitin-related modifier 1 | | Authors: | Capili, A.D, Lima, C.D. | | Deposit date: | 2007-04-02 | | Release date: | 2007-04-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl Interaction.
J.Mol.Biol., 369, 2007
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1WM2
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6VW2
 | | Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils | | Descriptor: | Islet amyloid polypeptide (SUMO-tagged) | | Authors: | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2020-02-18 | | Release date: | 2020-06-10 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils.
Nat.Struct.Mol.Biol., 27, 2020
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3PGE
 | | Structure of sumoylated PCNA | | Descriptor: | Proliferating cell nuclear antigen, SUMO-modified proliferating cell nuclear antigen | | Authors: | Freudenthal, B.D, Brogie, J.E, Gakhar, L, Washington, T. | | Deposit date: | 2010-11-01 | | Release date: | 2010-12-29 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen.
J.Mol.Biol., 406, 2011
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4OO1
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6DG4
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3IX6
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5VZJ
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1WM3
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8V9L
 | | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | | Authors: | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | | Deposit date: | 2023-12-08 | | Release date: | 2024-02-07 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
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5AEK
 | | Crystal structure of the human SENP2 C548S in complex with the human SUMO1 K48M F66W | | Descriptor: | SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 1 | | Authors: | Gallego, P, Grana-Montes, R, Espargaro, A, Castillo, V, Torrent, J, Lange, R, Papaleo, E, Lindorff-Larsend, K, Ventura, S, Reverter, D. | | Deposit date: | 2014-12-23 | | Release date: | 2016-01-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Stepping Back and Forward on Sumo Folding Evolution
To be Published
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2K1F
 | | SUMO-3 from Drosophila melanogaster (dsmt3) | | Descriptor: | CG4494-PA | | Authors: | Kumar, D, Misra, J.R, Misra, A.K, Chugh, J, Sharma, S, Hosur, R.V. | | Deposit date: | 2008-03-03 | | Release date: | 2009-03-10 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3).
Proteins, 75, 2009
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5XQM
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3KYD
 | | Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic | | Descriptor: | 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ... | | Authors: | Lima, C.D. | | Deposit date: | 2009-12-05 | | Release date: | 2010-02-16 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Active site remodelling accompanies thioester bond formation in the SUMO E1.
Nature, 463, 2010
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3ZO5
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4AUV
 | | Crystal Structure of the BRMS1 N-terminal region | | Descriptor: | ACETIC ACID, BREAST CANCER METASTASIS SUPPRESSOR 1, CHLORIDE ION, ... | | Authors: | Spinola-Amilibia, M, Rivera, J, Ortiz-Lombardia, M, Romero, A, Neira, J.L, Bravo, J. | | Deposit date: | 2012-05-22 | | Release date: | 2013-03-20 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | Brms151-98 and Brms151-84 are Crystal Oligomeric Coiled Coils with Different Oligomerization States, which Behave as Disordered Protein Fragments in Solution.
J.Mol.Biol., 425, 2013
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2IO2
 | | Crystal structure of human Senp2 in complex with RanGAP1-SUMO-1 | | Descriptor: | Ran GTPase-activating protein 1, Sentrin-specific protease 2, Small ubiquitin-related modifier 1 | | Authors: | Reverter, D, Lima, C.D. | | Deposit date: | 2006-10-09 | | Release date: | 2006-11-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.
Nat.Struct.Mol.Biol., 13, 2006
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2IO3
 | | Crystal structure of human Senp2 in complex with RanGAP1-SUMO-2 | | Descriptor: | Ran GTPase-activating protein 1, Sentrin-specific protease 2, Small ubiquitin-related modifier 2 | | Authors: | Reverter, D, Lima, C.D. | | Deposit date: | 2006-10-09 | | Release date: | 2006-11-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.
Nat.Struct.Mol.Biol., 13, 2006
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2IO0
 | | Crystal structure of human Senp2 in complex with preSUMO-2 | | Descriptor: | SULFATE ION, Sentrin-specific protease 2, Small ubiquitin-related modifier 2 precursor | | Authors: | Reverter, D, Lima, C.D. | | Deposit date: | 2006-10-09 | | Release date: | 2006-11-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.
Nat.Struct.Mol.Biol., 13, 2006
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2IO1
 | | Crystal structure of human Senp2 in complex with preSUMO-3 | | Descriptor: | Sentrin-specific protease 2, Small ubiquitin-related modifier 3 precursor | | Authors: | Reverter, D, Lima, C.D. | | Deposit date: | 2006-10-09 | | Release date: | 2006-11-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.
Nat.Struct.Mol.Biol., 13, 2006
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2NN6
 | | Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40 | | Descriptor: | 3'-5' exoribonuclease CSL4 homolog, Exosome complex exonuclease RRP4, Exosome complex exonuclease RRP40, ... | | Authors: | Lima, C.D. | | Deposit date: | 2006-10-23 | | Release date: | 2006-12-26 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Reconstitution, activities, and structure of the eukaryotic RNA exosome.
Cell(Cambridge,Mass.), 127, 2006
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