PDB: 231 件ウェブページステータス検索Chemie searchBIRD

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6UKW	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 10 分子名称: 4-[6-(3-{[2-(3-carboxypropanoyl)-4-fluoro-6-methoxy-1-benzothiophen-5-yl]oxy}propoxy)-5-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-06 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
6UKY	STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 12 分子名称: 4-(6-{3-[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-4-yl]propyl}-5-methoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain 著者 Lesburg, C.A. 登録日 2019-10-06 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
6VEL	Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody 66E8Fab 分子名称: 66E8 Fab Heavy Chain, 66E8 Fab Light Chain, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-01-02 公開日 2020-01-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography. Pnas Nexus, 1, 2022
8UZH	SUMO fused Trehalose Synthase (TreS) of Mycobacterium tuberculosis 分子名称: CALCIUM ION, SUMO fused Trehalose Synthase (TreS),Trehalose synthase/amylase TreS 著者 Pathirage, R, Ronning, D.R. 登録日 2023-11-15 公開日 2024-03-27 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift. Acs Infect Dis., 10, 2024
2PE6	Non-covalent complex between human SUMO-1 and human Ubc9 分子名称: SUMO-conjugating enzyme UBC9, Small ubiquitin-related modifier 1 著者 Capili, A.D, Lima, C.D. 登録日 2007-04-02 公開日 2007-04-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl Interaction. J.Mol.Biol., 369, 2007
1WM2	Crystal structure of human SUMO-2 protein 分子名称: Ubiquitin-like protein SMT3B 著者 Huang, W.-C, Ko, T.-P, Li, S.S.-L, Wang, A.H.-J. 登録日 2004-07-02 公開日 2004-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: implication on the functional differences of SUMO proteins Eur.J.Biochem., 271, 2004
6VW2	Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils 分子名称: Islet amyloid polypeptide (SUMO-tagged) 著者 Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. 登録日 2020-02-18 公開日 2020-06-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils. Nat.Struct.Mol.Biol., 27, 2020
3PGE	Structure of sumoylated PCNA 分子名称: Proliferating cell nuclear antigen, SUMO-modified proliferating cell nuclear antigen 著者 Freudenthal, B.D, Brogie, J.E, Gakhar, L, Washington, T. 登録日 2010-11-01 公開日 2010-12-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen. J.Mol.Biol., 406, 2011
4OO1	Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exosome complex component CSL4, ... 著者 Lima, C.D, Wasmuth, E.V. 登録日 2014-01-29 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA. Nature, 511, 2014
6DG4	Structure of the Chaetomium thermophilum Ulp1-like SUMO protease catalytic domain 分子名称: GLYCEROL, SULFATE ION, Ulp1-like SUMO protease 著者 Lima, C.D, Baytshtok, V. 登録日 2018-05-16 公開日 2018-07-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.442 Å) 主引用文献 Discovery and engineering of enhanced SUMO protease enzymes. J. Biol. Chem., 293, 2018
3IX6	Crystal structure of Thymidylate synthase thyA from Brucella melitensis 分子名称: Thymidylate synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-09-03 公開日 2009-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Thymidylate synthase thyA from Brucella melitensis To be Published
5VZJ	STRUCTURE OF A TWELVE COMPONENT MPP6-NUCLEAR RNA EXOSOME COMPLEX BOUND TO RNA 分子名称: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... 著者 Lima, C.D, Wasmuth, E.V. 登録日 2017-05-28 公開日 2017-08-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase. Elife, 6, 2017
1WM3	Crystal structure of human SUMO-2 protein 分子名称: Ubiquitin-like protein SMT3B 著者 Huang, W.-C, Ko, T.-P, Li, S.S.-L, Wang, A.H.-J. 登録日 2004-07-02 公開日 2004-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: implication on the functional differences of SUMO proteins Eur.J.Biochem., 271, 2004
8V9L	Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... 著者 Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. 登録日 2023-12-08 公開日 2024-02-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
5AEK	Crystal structure of the human SENP2 C548S in complex with the human SUMO1 K48M F66W 分子名称: SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 1 著者 Gallego, P, Grana-Montes, R, Espargaro, A, Castillo, V, Torrent, J, Lange, R, Papaleo, E, Lindorff-Larsend, K, Ventura, S, Reverter, D. 登録日 2014-12-23 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Stepping Back and Forward on Sumo Folding Evolution To be Published
2K1F	SUMO-3 from Drosophila melanogaster (dsmt3) 分子名称: CG4494-PA 著者 Kumar, D, Misra, J.R, Misra, A.K, Chugh, J, Sharma, S, Hosur, R.V. 登録日 2008-03-03 公開日 2009-03-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3). Proteins, 75, 2009
5XQM	NMR solution structure of SMO1, Sumo homologue in Caenorhabditis elegans 分子名称: Small ubiquitin-related modifier 著者 Gowda, C.M, Surana, P, Das, R. 登録日 2017-06-07 公開日 2017-11-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural and functional analysis of SMO-1, the SUMO homolog in Caenorhabditis elegans PLoS ONE, 12, 2017
3KYD	Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic 分子名称: 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ... 著者 Lima, C.D. 登録日 2009-12-05 公開日 2010-02-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463, 2010
3ZO5	Structure of SENP2-Loop1 in complex with preSUMO-2 分子名称: SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 2 著者 Alegre, K.O, Reverter, D. 登録日 2013-02-20 公開日 2014-01-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural Insights Into the Senp6 Loop1 Structure in Complex with Sumo2. Protein Sci., 23, 2014
4AUV	Crystal Structure of the BRMS1 N-terminal region 分子名称: ACETIC ACID, BREAST CANCER METASTASIS SUPPRESSOR 1, CHLORIDE ION, ... 著者 Spinola-Amilibia, M, Rivera, J, Ortiz-Lombardia, M, Romero, A, Neira, J.L, Bravo, J. 登録日 2012-05-22 公開日 2013-03-20 最終更新日 2019-11-06 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Brms151-98 and Brms151-84 are Crystal Oligomeric Coiled Coils with Different Oligomerization States, which Behave as Disordered Protein Fragments in Solution. J.Mol.Biol., 425, 2013
2IO2	Crystal structure of human Senp2 in complex with RanGAP1-SUMO-1 分子名称: Ran GTPase-activating protein 1, Sentrin-specific protease 2, Small ubiquitin-related modifier 1 著者 Reverter, D, Lima, C.D. 登録日 2006-10-09 公開日 2006-11-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat.Struct.Mol.Biol., 13, 2006
2IO3	Crystal structure of human Senp2 in complex with RanGAP1-SUMO-2 分子名称: Ran GTPase-activating protein 1, Sentrin-specific protease 2, Small ubiquitin-related modifier 2 著者 Reverter, D, Lima, C.D. 登録日 2006-10-09 公開日 2006-11-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat.Struct.Mol.Biol., 13, 2006
2IO0	Crystal structure of human Senp2 in complex with preSUMO-2 分子名称: SULFATE ION, Sentrin-specific protease 2, Small ubiquitin-related modifier 2 precursor 著者 Reverter, D, Lima, C.D. 登録日 2006-10-09 公開日 2006-11-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat.Struct.Mol.Biol., 13, 2006
2IO1	Crystal structure of human Senp2 in complex with preSUMO-3 分子名称: Sentrin-specific protease 2, Small ubiquitin-related modifier 3 precursor 著者 Reverter, D, Lima, C.D. 登録日 2006-10-09 公開日 2006-11-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat.Struct.Mol.Biol., 13, 2006
2NN6	Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40 分子名称: 3'-5' exoribonuclease CSL4 homolog, Exosome complex exonuclease RRP4, Exosome complex exonuclease RRP40, ... 著者 Lima, C.D. 登録日 2006-10-23 公開日 2006-12-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell(Cambridge,Mass.), 127, 2006

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