3S7D
| |
3S7F
| |
2UWQ
| |
2N06
| Mdmx-298 | Descriptor: | 4-[[(4S,5R)-5-(4-chlorophenyl)-4-(3-methoxyphenyl)-2-(4-methoxy-2-propan-2-yloxy-phenyl)-4,5-dihydroimidazol-1-yl]carbonyl]piperazin-2-one, Protein Mdm4 | Authors: | Grace, C.R, Kriwacki, R.W. | Deposit date: | 2015-03-04 | Release date: | 2016-01-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428, 2016
|
|
2ROC
| Solution structure of Mcl-1 Complexed with Puma | Descriptor: | Bcl-2-binding component 3, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | Authors: | Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G. | Deposit date: | 2008-03-17 | Release date: | 2008-07-08 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1 J.Mol.Biol., 380, 2008
|
|
2FHI
| SUBSTRATE ANALOG (IB2) COMPLEX WITH THE HIS 96 ASN SUBSTITUTION OF THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT | Descriptor: | FRAGILE HISTIDINE TRIAD PROTEIN, P1-P2-METHYLENE-P3-THIO-DIADENOSINE TRIPHOSPHATE | Authors: | Pace, H.C, Garrison, P.N, Robinson, A.K, Barnes, L.D, Draganescu, A, Rosler, A, Blackburn, G.M, Siprashvili, Z, Croce, C.M, Heubner, K, Brenner, C. | Deposit date: | 1998-04-01 | Release date: | 1998-06-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
2ROD
| Solution Structure of MCL-1 Complexed with NoxaA | Descriptor: | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Noxa | Authors: | Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G. | Deposit date: | 2008-03-17 | Release date: | 2008-07-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1 J.Mol.Biol., 380, 2008
|
|
2KZU
| DAXX helical bundle (DHB) domain / Rassf1C complex | Descriptor: | Death-associated protein 6, Ras association (RalGDS/AF-6) domain family 1 | Authors: | Escobar-Cabrera, E, Lau, D.K.W, Giovinazzi, S, Ishov, A.M, McIntosh, L.P. | Deposit date: | 2010-06-25 | Release date: | 2010-12-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C. Structure, 18, 2010
|
|
2Y9U
| Structural basis of p63a SAM domain mutants involved in AEC syndrome | Descriptor: | SULFATE ION, TUMOR PROTEIN 63 | Authors: | Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D. | Deposit date: | 2011-02-16 | Release date: | 2011-08-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome. FEBS J., 278, 2011
|
|
6V4E
| Crystal Structure Analysis of Zebra Fish MDM | Descriptor: | Protein Mdm4, Stapled peptide QSQQTF(0EH)NLWRLL(MK8)QN(NH2) | Authors: | Seo, H.-S, Dhe-Paganon, S. | Deposit date: | 2019-11-27 | Release date: | 2020-04-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Identification of a Structural Determinant for Selective Targeting of HDMX. Structure, 28, 2020
|
|
6V4G
| Crystal Structure Analysis of Zebra fish MDMX | Descriptor: | Protein Mdm4, SULFATE ION, Stapled peptide QSQQTF(0EH)NLWRLE(MK8)QN(NH2) | Authors: | Seo, H.-S, Dhe-Paganon, S. | Deposit date: | 2019-11-27 | Release date: | 2020-04-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Identification of a Structural Determinant for Selective Targeting of HDMX. Structure, 28, 2020
|
|
6V4H
| Crystal Structure Analysis of Zebra Fish MDMX | Descriptor: | Protein Mdm4, Stapled Peptide LSQETF(0EH)DLWKLL(MK8)EN(NH2) | Authors: | Seo, H.-S, Dhe-Paganon, S. | Deposit date: | 2019-11-27 | Release date: | 2020-04-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Identification of a Structural Determinant for Selective Targeting of HDMX. Structure, 28, 2020
|
|
6V4F
| Crystal Structure Analysis of Zebra Fish MDMX | Descriptor: | Protein Mdm4, SULFATE ION, Stapled Peptide LSQETF(0EH)DLWKLE(MK8)EN(NH2) | Authors: | Seo, H.-S, Dhe-Paganon, S. | Deposit date: | 2019-11-27 | Release date: | 2020-04-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Identification of a Structural Determinant for Selective Targeting of HDMX. Structure, 28, 2020
|
|
4G83
| |
8INE
| |
8INF
| |
8FLA
| |
8FLB
| |
1TTV
| NMR Structure of a Complex Between MDM2 and a Small Molecule Inhibitor | Descriptor: | 1-{[4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]CARBONYL}PIPERAZINE, Ubiquitin-protein ligase E3 Mdm2 | Authors: | Fry, D.C, Emerson, S.D, Palme, S, Vu, B.T, Liu, C.M, Podlaski, F. | Deposit date: | 2004-06-23 | Release date: | 2005-01-04 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | NMR structure of a complex between MDM2 and a small molecule inhibitor. J.Biomol.Nmr, 30, 2004
|
|
3VD0
| structure of p73 DNA binding domain tetramer modulates p73 transactivation | Descriptor: | DNA (5'-D(*CP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*G)-3'), Tumor protein p73, ZINC ION | Authors: | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | Deposit date: | 2012-01-04 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3VD1
| structure of p73 DNA binding domain tetramer modulates p73 transactivation | Descriptor: | DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), Tumor protein p73, ZINC ION | Authors: | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | Deposit date: | 2012-01-04 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3VD2
| structure of p73 DNA binding domain tetramer modulates p73 transactivation | Descriptor: | DNA (5'-D(*AP*TP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*AP*T)-3'), Tumor protein p73, ZINC ION | Authors: | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | Deposit date: | 2012-01-04 | Release date: | 2012-04-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
5KBD
| |
2VYR
| Structure of human MDM4 N-terminal domain bound to a single domain antibody | Descriptor: | HUMAN SINGLE DOMAIN ANTIBODY, MDM4 PROTEIN, SULFATE ION | Authors: | Yu, G.W, Vaysburd, M, Allen, M.D, Settanni, G, Fersht, A.R. | Deposit date: | 2008-07-28 | Release date: | 2008-11-25 | Last modified: | 2013-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Human Mdm4 N-Terminal Domain Bound to a Single-Domain Antibody. J.Mol.Biol., 385, 2009
|
|
4G82
| |