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5AWR
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BU of 5awr by Molmil
Crystal structure of the SGIP1 mu homology domain in the P4212 space group
Descriptor: SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
Authors:Shimada, A, Yamaguchi, A, Kohda, D.
Deposit date:2015-07-08
Release date:2016-07-06
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
5AWT
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BU of 5awt by Molmil
Crystal structure of the SGIP1 mu homology domain in complex with an Eps15 fragment containing two DPF motifs (YDPFGGDPFKG)
Descriptor: Epidermal growth factor receptor substrate 15, SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
Authors:Shimada, A, Yamaguchi, A, Kohda, D.
Deposit date:2015-07-08
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
5AWU
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BU of 5awu by Molmil
Crystal structure of the SGIP1 mu homology domain in complex with an Eps15 fragment containing two DPF motifs (YDPFKGSDPFA)
Descriptor: Epidermal growth factor receptor substrate 15, SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
Authors:Shimada, A, Yamaguchi, A, Kohda, D.
Deposit date:2015-07-08
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
5AWS
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BU of 5aws by Molmil
Crystal structure of the SGIP1 mu homology domain in the P1 space group
Descriptor: SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
Authors:Shimada, A, Yamaguchi, A, Kohda, D.
Deposit date:2015-07-08
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
6YET
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BU of 6yet by Molmil
Second EH domain of AtEH1/Pan1
Descriptor: CALCIUM ION, Calcium-binding EF hand family protein
Authors:Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K.
Deposit date:2020-03-25
Release date:2021-03-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
6YEU
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BU of 6yeu by Molmil
Second EH domain of AtEH1/Pan1
Descriptor: CALCIUM ION, Calcium-binding EF hand family protein
Authors:Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K.
Deposit date:2020-03-25
Release date:2021-03-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
8WU1
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BU of 8wu1 by Molmil
Cryo-EM structure of CB1-beta-arrestin1 complex
Descriptor: Beta-arrestin-1, Cannabinoid receptor 1,Vasopressin V2 receptor, Fab30 heavy chain, ...
Authors:Liao, Y, Zhang, H, Shen, Q, Cai, C.
Deposit date:2023-10-19
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of CB1-beta-arrestin1 complex
to be published
2WTR
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BU of 2wtr by Molmil
Full length Arrestin2
Descriptor: BARIUM ION, BETA-ARRESTIN-1
Authors:Zhou, H.G, Standfuss, J, Watson, K.A, Krasel, C.
Deposit date:2009-09-21
Release date:2009-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A New Dimeric Crystal Form for Arrestin2
To be Published
1EDU
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BU of 1edu by Molmil
CRYSTAL STRUCTURE OF THE ENTH DOMAIN OF RAT EPSIN 1
Descriptor: 1,2-ETHANEDIOL, EH domain binding protein EPSIN
Authors:Hyman, J.H, Chen, H, Decamilli, P, Brunger, A.T.
Deposit date:2000-01-28
Release date:2000-05-10
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF).
J.Cell Biol., 149, 2000
7DFB
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BU of 7dfb by Molmil
Crystal of Arrestin2-V2Rpp-6-7-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DF9
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BU of 7df9 by Molmil
Crystal of Arrestin2-V2Rpp-1-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DFA
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BU of 7dfa by Molmil
Crystal of Arrestin2-V2Rpp-4-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DFC
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BU of 7dfc by Molmil
Crystal of Arrestin2-V2Rpp-3-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
4IKN
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BU of 4ikn by Molmil
Crystal structure of adaptor protein complex 3 (AP-3) mu3A subunit C-terminal domain, in complex with a sorting peptide from TGN38
Descriptor: AP-3 complex subunit mu-1, Trans-Golgi network integral membrane protein TGN38
Authors:Mardones, G.A, Kloer, D.P, Burgos, P.V, Bonifacino, J.S, Hurley, J.H.
Deposit date:2012-12-26
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Structural basis for the recognition of tyrosine-based sorting signals by the mu 3A subunit of the AP-3 adaptor complex.
J.Biol.Chem., 288, 2013
3ZY7
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BU of 3zy7 by Molmil
Crystal structure of computationally redesigned gamma-adaptin appendage domain forming a symmetric homodimer
Descriptor: AP-1 COMPLEX SUBUNIT GAMMA-1, DI(HYDROXYETHYL)ETHER, ISOPROPYL ALCOHOL
Authors:Stranges, P.B, Machius, M, Miley, M.J, Tripathy, A, Kuhlman, B.
Deposit date:2011-08-17
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Computational Design of a Symmetric Homodimer Using Beta-Strand Assembly.
Proc.Natl.Acad.Sci.USA, 108, 2011
6NI2
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BU of 6ni2 by Molmil
Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Descriptor: Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ...
Authors:Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J.
Deposit date:2018-12-26
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nat.Struct.Mol.Biol., 26, 2019
2VJ0
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BU of 2vj0 by Molmil
Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, in complex with an FXDNF peptide from amphiphysin1 and a WVXF peptide from synaptojanin P170
Descriptor: AMPHIPHYSIN, AP-2 COMPLEX SUBUNIT ALPHA-2, BENZAMIDINE, ...
Authors:Ford, M.G.J, Praefcke, G.J.K, McMahon, H.T.
Deposit date:2007-12-06
Release date:2007-12-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Solitary and Repetitive Binding Motifs for the Ap2 Complex {Alpha}-Appendage in Amphiphysin and Other Accessory Proteins.
J.Biol.Chem., 283, 2008
5C7Z
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BU of 5c7z by Molmil
AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
Descriptor: AP-2 complex subunit mu, Integrin alpha-4
Authors:Owen, D.J, Evans, P.R, Wilson, T.A.
Deposit date:2015-06-25
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
To Be Published
6IF2
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BU of 6if2 by Molmil
Complex structure of Rab35 and its effector RUSC2
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Iporin, MAGNESIUM ION, ...
Authors:Lin, L, Zhu, J, Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6IF3
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BU of 6if3 by Molmil
Complex structure of Rab35 and its effector ACAP2
Descriptor: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Lin, L, Zhu, J, Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
1JSY
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BU of 1jsy by Molmil
Crystal structure of bovine arrestin-2
Descriptor: Bovine arrestin-2 (full length)
Authors:Milano, S.K, Pace, H.C, Kim, Y.M, Brenner, C, Benovic, J.L.
Deposit date:2001-08-19
Release date:2002-03-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis.
Biochemistry, 41, 2002
7P3Y
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BU of 7p3y by Molmil
Homology model of the full-length AP-3 complex in an intermediate open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
7P3Z
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BU of 7p3z by Molmil
Homology model of the full-length AP-3 complex in a stretched open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (10.5 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
7P3X
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BU of 7p3x by Molmil
Homology model of the full-length AP-3 complex in a compact open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
1G4R
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BU of 1g4r by Molmil
CRYSTAL STRUCTURE OF BOVINE BETA-ARRESTIN 1
Descriptor: BETA-ARRESTIN 1
Authors:Schubert, C, Han, M.
Deposit date:2000-10-27
Release date:2001-10-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation.
Structure, 9, 2001

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