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7RW8
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BU of 7rw8 by Molmil
AP2 bound to heparin in the closed conformation
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Baker, R.W, Hollopeter, G, Partlow, E.A.
Deposit date:2021-08-19
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
7RW9
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BU of 7rw9 by Molmil
AP2 bound to heparin in the bowl conformation
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Baker, R.W, Hollopeter, G, Partlow, E.A.
Deposit date:2021-08-19
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
2G30
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BU of 2g30 by Molmil
beta appendage of AP2 complexed with ARH peptide
Descriptor: 16-mer peptide from Low density lipoprotein receptor adapter protein 1, AP-2 complex subunit beta-1, peptide sequence AAF
Authors:Edeling, M.A, Collins, B.M, Traub, L.M, Owen, D.J.
Deposit date:2006-02-17
Release date:2006-03-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular Switches Involving the AP-2 beta2 Appendage Regulate Endocytic Cargo Selection and Clathrin Coat Assembly
Dev.Cell, 10, 2006
6RH5
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BU of 6rh5 by Molmil
Solution structure and 1H, 13C and 15N chemical shift assignments for NECAP1 PHear domain
Descriptor: Adaptin ear-binding coat-associated protein 1
Authors:Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
5AHV
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BU of 5ahv by Molmil
Cryo-EM structure of helical ANTH and ENTH tubules on PI(4,5)P2-containing membranes
Descriptor: ANTH DOMAIN OF ENDOCYTIC ADAPTOR SLA2, ENTH DOMAIN OF EPSIN ENT1
Authors:Skruzny, M, Desfosses, A, Prinz, S, Dodonova, S.O, Gieras, A, Uetrecht, C, Jakobi, A.J, Abella, M, Hagen, W.J.H, Schulz, J, Meijers, R, Rybin, V, Briggs, J.A.G, Sachse, C, Kaksonen, M.
Deposit date:2015-02-10
Release date:2015-05-06
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:An Organized Co-Assembly of Clathrin Adaptors is Essential for Endocytosis.
Dev.Cell, 33, 2015
1H0A
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BU of 1h0a by Molmil
Epsin ENTH bound to Ins(1,4,5)P3
Descriptor: 1,4-DIETHYLENE DIOXIDE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, EPSIN
Authors:Ford, M.G.J, McMahon, H.T, Evans, P.R.
Deposit date:2002-06-12
Release date:2002-10-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Curvature of Clathrin-Coated Pits Driven by Epsin
Nature, 419, 2002
5VKY
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BU of 5vky by Molmil
Yeast Tda2 (YER071C) - a dynein light chain family member that works independently of the dynein motor complex and microtubules.
Descriptor: Topoisomerase I damage affected protein 2
Authors:McDonald, S.M, Di Pietro, S.M, Peersen, O.B.
Deposit date:2017-04-24
Release date:2017-07-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Novel function of a dynein light chain in actin assembly during clathrin-mediated endocytosis.
J. Cell Biol., 216, 2017
5JP2
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BU of 5jp2 by Molmil
Fcho1 Mu homology domain (Danio Rerio) with bound Eps15 peptide
Descriptor: Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
Authors:McCoy, A.J, Wrobel, A, Owen, D.J.
Deposit date:2016-05-03
Release date:2016-06-08
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
5J08
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BU of 5j08 by Molmil
Crystal structure of yeast Ent5 N-terminal domain-native P21
Descriptor: Epsin-5
Authors:Zhang, F, Song, Y, Li, X, Teng, M.K.
Deposit date:2016-03-28
Release date:2016-10-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae
Biochem.Biophys.Res.Commun., 477, 2016
5CMW
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BU of 5cmw by Molmil
Crystal structure of yeast Ent5 N-terminal domain-soaked in KI
Descriptor: Epsin-5, GLYCEROL, IODIDE ION
Authors:Zhang, F, Song, Y, Li, X, Teng, M.K.
Deposit date:2015-07-17
Release date:2016-07-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae
Biochem.Biophys.Res.Commun., 477, 2016
5CMY
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BU of 5cmy by Molmil
Crystal structure of yeast Ent5 N-terminal domain-native
Descriptor: Epsin-5, GLYCEROL
Authors:Zhang, F, Song, Y, Li, X, Teng, M.K.
Deposit date:2015-07-17
Release date:2016-07-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and functional insight into the N-terminal domain of the clathrin adaptor Ent5 from Saccharomyces cerevisiae
Biochem.Biophys.Res.Commun., 477, 2016
4NEE
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BU of 4nee by Molmil
crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit sigma, Protein Nef
Authors:Hurley, J.H, Bonifacino, J.S, Ren, X, Park, S.Y.
Deposit date:2013-10-29
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8841 Å)
Cite:How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife, 3, 2014
7JXV
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BU of 7jxv by Molmil
ANTH domain of CALM (clathrin-assembly lymphoid myeloid leukemia protein) bound to ubiquitin
Descriptor: Phosphatidylinositol-binding clathrin assembly protein, Ubiquitin
Authors:Pashkova, N, Gakhar, L, Schnicker, N.J, Piper, R.C.
Deposit date:2020-08-28
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals.
Elife, 10, 2021
7UX3
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BU of 7ux3 by Molmil
Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-05-04
Release date:2023-05-10
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
3IDW
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BU of 3idw by Molmil
Crystal structure of Sla1 homology domain 2
Descriptor: Actin cytoskeleton-regulatory complex protein SLA1
Authors:Di Pietro, S.M, Cascio, D, Bowie, J.U, Payne, G.S.
Deposit date:2009-07-21
Release date:2010-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain.
Embo J., 29, 2010
8D9W
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BU of 8d9w by Molmil
beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.H, Hurley, J.H.
Deposit date:2022-06-11
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9V
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BU of 8d9v by Molmil
gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes
Descriptor: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9S
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BU of 8d9s by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1
Descriptor: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9T
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BU of 8d9t by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on gamma-Arf1
Descriptor: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9R
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BU of 8d9r by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on gamma-Arf1
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9U
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BU of 8d9u by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4G
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BU of 8d4g by Molmil
gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (11.6 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4C
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BU of 8d4c by Molmil
beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4E
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BU of 8d4e by Molmil
Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4F
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BU of 8d4f by Molmil
beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022

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