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2MTX	Protection against experimental P. falciparum malaria is associated with short AMA-1 peptide analogue alpha-helical structures Descriptor: Apical membrane antigen-1 Authors: Cubillos, M, Salazar, L, Torres, L, Sandoval, M, Patarroyo, M.E. Deposit date: 2014-09-01 Release date: 2015-02-04 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Protection against experimental P. falciparum malaria is associated with short AMA-1 peptide analogue alpha-helical structures To be Published
3SRI	Crystal structure of Plasmodium falciparum AMA1 in complex with a 29aa PfRON2 peptide Descriptor: Apical membrane antigen 1, Rhoptry neck protein 2 Authors: Vulliez-Le Normand, B, Saul, F.A, Bentley, G.A. Deposit date: 2011-07-07 Release date: 2012-07-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural and functional insights into the malaria parasite moving junction complex. Plos Pathog., 8, 2012
4R1A	Crystal Structure of FVO strain Plasmodium falciparum AMA1 Descriptor: Apical membrane antigen 1 Authors: Lim, S.S, Norton, R.S, McGowan, S. Deposit date: 2014-08-04 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO. Biochemistry, 53, 2014
5MC9	Crystal structure of the heterotrimeric integrin-binding region of laminin-111 Descriptor: CALCIUM ION, Laminin subunit alpha-1, Laminin subunit beta-1, ... Authors: Pulido, D, Hohenester, E. Deposit date: 2016-11-09 Release date: 2017-02-08 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111. Structure, 25, 2017
6N7Q	Plasmodium falciparum FVO apical membrane antigen 1 (AMA1) bound to cyclised RON2 peptide Descriptor: Apical membrane antigen-1, RON2 peptide Authors: McGowan, S, Drinkwater, N. Deposit date: 2018-11-28 Release date: 2019-01-30 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe. ChemMedChem, 14, 2019
6N87	Plasmodium falciparum FVO apical membrane antigen 1 (AMA1) bound to MTSL spin-labelled cyclised RON2 peptide Descriptor: Apical membrane antigen-1, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, backbone-cyclised peptide bcRON2hp Authors: McGowan, S, Drinkwater, N. Deposit date: 2018-11-28 Release date: 2019-01-30 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.588 Å) Cite: Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe. ChemMedChem, 14, 2019
6ZOQ	Oestrogen receptor ligand binding domain in complex with compound 16 Descriptor: Estrogen receptor, ~{N}-[4-[(6~{S},8~{R})-7-[(1-fluoranylcyclopropyl)methyl]-8-methyl-2,6,8,9-tetrahydropyrazolo[4,3-f]isoquinolin-6-yl]-3-methoxy-phenyl]-1-(3-fluoranylpropyl)azetidin-3-amine Authors: Breed, J. Deposit date: 2020-07-07 Release date: 2021-01-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist. J.Med.Chem., 63, 2020
6ZOR	Oestrogen receptor ligand binding domain in complex with compound 28 Descriptor: 6-[(6~{S},8~{R})-8-methyl-7-[2,2,2-tris(fluoranyl)ethyl]-3,6,8,9-tetrahydropyrazolo[4,3-f]isoquinolin-6-yl]-~{N}-(1-propylazetidin-3-yl)pyridin-3-amine, Estrogen receptor Authors: Breed, J. Deposit date: 2020-07-07 Release date: 2021-01-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist. J.Med.Chem., 63, 2020
6ZOS	Oestrogen receptor ligand binding domain in complex with compound 18 Descriptor: 6-[(6~{S},8~{R})-7-[(1-fluoranylcyclopropyl)methyl]-8-methyl-2,6,8,9-tetrahydropyrazolo[4,3-f]isoquinolin-6-yl]-~{N}-[1-(3-fluoranylpropyl)azetidin-3-yl]pyridin-3-amine, Estrogen receptor Authors: Breed, J. Deposit date: 2020-07-07 Release date: 2021-01-20 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist. J.Med.Chem., 63, 2020
7QVJ	ESTROGEN RECEPTOR ALPHA IN COMPLEX WITH COMPOUND 29 Descriptor: 2,2-bis(fluoranyl)-3-[(1~{R},3~{R})-1-[6-fluoranyl-3-[2-(3-fluoranylpropylamino)ethoxy]-2-methyl-phenyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]propan-1-ol, Estrogen receptor Authors: Breed, J. Deposit date: 2022-01-21 Release date: 2023-02-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists. J.Med.Chem., 66, 2023
7QVL	OESTROGEN RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH COMPOUND 38 Descriptor: (2~{R})-3-[(1~{R},3~{R})-1-[5-fluoranyl-2-[2-(3-fluoranylpropylamino)ethoxy]-3-methyl-pyridin-4-yl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-2-methyl-propanoic acid, Estrogen receptor Authors: Breed, J. Deposit date: 2022-01-21 Release date: 2023-02-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists. J.Med.Chem., 66, 2023
8DMK	Cryo-EM reveals the molecular basis of laminin polymerization and LN-lamininopathies Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Laminin subunit alpha-1, ... Authors: Kulczyk, A.W. Deposit date: 2022-07-08 Release date: 2023-02-01 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM reveals the molecular basis oflaminin polymerization and LN-lamininopathies. Nat Commun, 14, 2023