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1GX5
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Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Bressanelli, S, Rey, F.A.
登録日2002-03-27
公開日2002-04-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
3NFH
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BU of 3nfh by Molmil
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)
分子名称: DNA-directed RNA polymerase I subunit RPA49
著者Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P.
登録日2010-06-10
公開日2010-09-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFI
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BU of 3nfi by Molmil
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DNA-directed RNA polymerase I subunit RPA49
著者Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P.
登録日2010-06-10
公開日2010-09-08
最終更新日2015-03-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ4
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase
著者Antonysamy, s.s.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3N6L
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BU of 3n6l by Molmil
The crystal structure of RNA-dependent RNA polymerase of EV71 virus
分子名称: NICKEL (II) ION, RNA-dependent RNA polymerase
著者Wu, Y, Rao, Z.H.
登録日2010-05-26
公開日2011-06-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
1ZYR
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BU of 1zyr by Molmil
Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ...
著者Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E.
登録日2005-06-10
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Cell(Cambridge,Mass.), 122, 2005
7UM0
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BU of 7um0 by Molmil
Structure of the phage AR9 non-virion RNA polymerase holoenzyme in complex with two DNA oligonucleotides containing the AR9 P077 promoter as determined by cryo-EM
分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, DNA-directed RNA polymerase, ...
著者Leiman, P.G, Fraser, A, Sokolova, M.L.
登録日2022-04-05
公開日2022-07-06
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase.
Nat Commun, 13, 2022
5D98
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Influenza C Virus RNA-dependent RNA Polymerase - Space group P43212
分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Hengrung, N, El Omari, K, Serna Martin, I, Vreede, F.T, Cusack, S, Rambo, R.P, Vonrhein, C, Bricogne, G, Stuart, D.I, Grimes, J.M, Fodor, E.
登録日2015-08-18
公開日2015-10-21
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
Nature, 527, 2015
4NC8
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BU of 4nc8 by Molmil
N-terminal domain of delta-subunit of RNA polymerase complexed with nickel ions
分子名称: DNA-directed RNA polymerase subunit delta, NICKEL (II) ION
著者Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M.
登録日2013-10-24
公開日2014-07-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
4NC7
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BU of 4nc7 by Molmil
N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions
分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION
著者Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M.
登録日2013-10-24
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
4PN0
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BU of 4pn0 by Molmil
Structure of S. pombe Pct1 RNA triphosphatase
分子名称: mRNA-capping enzyme subunit beta
著者Lima, C.D, Doamekpor, S.K.
登録日2014-05-22
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
4PN1
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Structure of S. pombe Pct1 RNA triphosphatase in complex with the Spt5 CTD
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Synthetic peptide, ...
著者Lima, C.D, Doamekpor, S.K.
登録日2014-05-22
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
7F4G
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BU of 7f4g by Molmil
Structure of RPAP2-bound RNA polymerase II
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y.
登録日2021-06-18
公開日2021-07-07
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Cell Rep, 39, 2022
7NKX
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BU of 7nkx by Molmil
RNA polymerase II-Spt4/5-nucleosome-Chd1 structure
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ...
著者Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
登録日2021-02-19
公開日2021-08-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
2R7Z
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BU of 2r7z by Molmil
Cisplatin lesion containing RNA polymerase II elongation complex
分子名称: 5'-D(*CP*AP*AP*GP*TP*AP*G)-3', 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3', 5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3', ...
著者Damsma, G.E, Alt, A, Brueckner, F, Carell, T, Cramer, P.
登録日2007-09-10
公開日2007-11-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Mechanism of transcriptional stalling at cisplatin-damaged DNA.
Nat.Struct.Mol.Biol., 14, 2007
7XSZ
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BU of 7xsz by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC115)
分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
著者Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2022-05-15
公開日2022-09-07
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XTD
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BU of 7xtd by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC58oct)
分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
著者Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2022-05-16
公開日2022-09-07
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XSX
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BU of 7xsx by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC49)
分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
著者Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2022-05-15
公開日2022-09-07
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XSE
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BU of 7xse by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC42)
分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
著者Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2022-05-13
公開日2022-09-07
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XT7
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BU of 7xt7 by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC49B)
分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
著者Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2022-05-16
公開日2022-10-12
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
7XTI
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BU of 7xti by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC58hex)
分子名称: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
著者Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2022-05-17
公開日2022-10-12
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-20
公開日2023-05-03
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BZ1
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RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
登録日2022-12-14
公開日2023-05-03
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023

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