PDB: 8254 件ウェブページステータス検索Chemie searchBIRD

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8OEU	Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. 登録日 2023-03-13 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
7O4L	Yeast TFIIH in the expanded state within the pre-initiation complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. 登録日 2021-04-06 公開日 2021-06-16 最終更新日 2021-08-04 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
7O4K	Yeast TFIIH in the contracted state within the pre-initiation complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. 登録日 2021-04-06 公開日 2021-06-16 最終更新日 2021-08-04 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening. Cell, 184, 2021
3J1N	Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module 分子名称: DNA-directed RNA polymerase II subunit RPABC1, DNA-directed RNA polymerase II subunit RPABC2, DNA-directed RNA polymerase II subunit RPABC3, ... 著者 Asturias, F.J, Imasaki, T. 登録日 2012-03-29 公開日 2013-03-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Interaction of the mediator head module with RNA polymerase II. Structure, 20, 2012
3H3V	Yeast RNAP II containing poly(A)-signal sequence in the active site 分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3', 5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3', ... 著者 Dengl, S, Cramer, P. 登録日 2009-04-17 公開日 2009-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro J.Biol.Chem., 284, 2009
6XI8	Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ... 著者 van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L. 登録日 2020-06-19 公開日 2021-04-28 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structure of TFIIK for phosphorylation of CTD of RNA polymerase II. Sci Adv, 7, 2021
7ML3	General transcription factor TFIIH (weak binding) 分子名称: BJ4_G0050160.mRNA.1.CDS.1, General transcription and DNA repair factor IIH, General transcription and DNA repair factor IIH helicase subunit XPB, ... 著者 Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. 登録日 2021-04-27 公開日 2022-02-02 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
1A1D	YEAST RNA POLYMERASE SUBUNIT RPB8, NMR, MINIMIZED AVERAGE STRUCTURE, ALPHA CARBONS ONLY 分子名称: RNA POLYMERASE 著者 Krapp, S, Kelly, G, Reischl, J, Weinzierl, R, Matthews, S. 登録日 1997-12-10 公開日 1999-03-02 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Eukaryotic RNA polymerase subunit RPB8 is a new relative of the OB family. Nat.Struct.Biol., 5, 1998
7KUE	CryoEM structure of Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ... 著者 van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L. 登録日 2020-11-24 公開日 2021-04-28 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of TFIIK for phosphorylation of CTD of RNA polymerase II. Sci Adv, 7, 2021
3J1O	Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module 分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... 著者 Asturias, F.J, Imasaki, T. 登録日 2012-03-29 公開日 2013-03-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Interaction of the mediator head module with RNA polymerase II. Structure, 20, 2012
7Z43	Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B 分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Cusack, S, Drncova, P. 登録日 2022-03-03 公開日 2022-05-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.123 Å) 主引用文献 Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18, 2022
7Z4O	Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Cusack, S, Pflug, A. 登録日 2022-03-04 公開日 2022-05-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.412 Å) 主引用文献 Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. Plos Pathog., 18, 2022
8PNP	Influenza A/H7N9 polymerase in pre-initiation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 51-mer vRNA loop (v51_mut_S), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-30 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.49 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8PNQ	Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-30 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8PM0	Influenza A/H7N9 polymerase in replicase-like conformation in pre-initiation state with Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, Polymerase acidic protein, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-27 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8R3K	Influenza A/H7N9 polymerase in self-stalled pre-termination state, with Pol II pS5 CTD peptide mimic bound in site 1A/2A. 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Cusack, S. 登録日 2023-11-09 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8R3L	Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 3' vRNA end (51-mer vRNA loop), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2023-11-09 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8POH	Influenza A/H7N9 polymerase symmetric dimer bound to the promoter (PA K289A/C489R) 分子名称: 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, Polymerase acidic protein, ... 著者 Arragain, B, Cusack, S. 登録日 2023-07-04 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8RBZ	Structure of Integrator-PP2A-SOSS-CTD post-termination complex 分子名称: DNA-directed RNA polymerase subunit, DSS1, Integrator complex subunit 1, ... 著者 Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. 登録日 2023-12-05 公開日 2024-02-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
4GWP	Structure of the Mediator Head Module from S. cerevisiae 分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... 著者 Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D. 登録日 2012-09-03 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II. Proc.Natl.Acad.Sci.USA, 109, 2012
4YH1	Structure of Human Scp1 bound to cis-proline peptidomimetic CTD phospho-Ser5 peptide 分子名称: A small phosphatase 1, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION 著者 Mayfield, J.E, Zhang, Y. 登録日 2015-02-26 公開日 2015-09-16 最終更新日 2015-10-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015
4YGY	Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide 分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, peptidomimetic CTD phospho-Ser5 peptide 著者 Mayfield, J.E, Zhang, Y. 登録日 2015-02-26 公開日 2015-09-16 最終更新日 2015-10-28 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015
6DT8	Bacteriophage N4 RNA polymerase II elongation complex 1 分子名称: DNA (5'-D(P*AP*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*UP*GP*G)-3'), RNAP1, ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-06-15 公開日 2018-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
6DTA	Bacteriophage N4 RNA polymerase II elongation complex 2 分子名称: DNA (5'-D(P*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-06-15 公開日 2018-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.694 Å) 主引用文献 Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II. J. Biol. Chem., 293, 2018
4JXT	CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD 分子名称: DNA-directed RNA polymerase II subunit RPB1, Regulation of nuclear pre-mRNA domain-containing protein 1A, UNKNOWN ATOM OR ION 著者 Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) 登録日 2013-03-28 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014

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