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8UKQ	RNA polymerase II elongation complex with Fapy-dG lesion in apo state Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Hou, P, Oh, J, Wang, D. Deposit date: 2023-10-15 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKS	RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Hou, P, Oh, J, Wang, D. Deposit date: 2023-10-15 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
1ESY	NMR STRUCTURE OF STEM LOOP SL2 OF THE HIV-1 PSI RNA PACKAGING SIGNAL REVEALS A NOVEL A-U-A BASE-TRIPLE PLATFORM Descriptor: RNA (5'-R(P*GP*GP*CP*GP*AP*CP*UP*GP*GP*UP*GP*AP*GP*UP*AP*CP*GP*CP*C)-3') Authors: Amarasinghe, G.K, De Guzman, R.N, Turner, R.B, Summers, M.F. Deposit date: 2000-04-11 Release date: 2000-05-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: NMR structure of stem-loop SL2 of the HIV-1 psi RNA packaging signal reveals a novel A-U-A base-triple platform. J.Mol.Biol., 299, 2000
1DQH	CRYSTAL STRUCTURE OF HELIX II OF THE X. LAEVIS SOMATIC 5S RRNA WITH A CYTOSINE BULGE IN TWO CONFORMATIONS Descriptor: RNA (5'-R(*CP*AP*GP*GP*GP*UP*CP*GP*GP*C)-3'), RNA (5'-R(*GP*CP*CP*AP*CP*CP*CP*UP*G)-3') Authors: Xiong, Y, Sundaralingam, M. Deposit date: 2000-01-04 Release date: 2000-11-13 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Two crystal forms of helix II of Xenopus laevis 5S rRNA with a cytosine bulge. RNA, 6, 2000
4U37	Native 7mer-RNA duplex Descriptor: RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3') Authors: Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. Deposit date: 2014-07-18 Release date: 2014-08-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs. J.Am.Chem.Soc., 136, 2014
4U34	Crystal Structures of RNA Duplexes Containing 2-thio-Uridine Descriptor: RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3') Authors: Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. Deposit date: 2014-07-18 Release date: 2014-08-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs. J.Am.Chem.Soc., 136, 2014
4U35	Crystal Structures of RNA Duplexes Containing 2-thio-Uridine Descriptor: RNA (5'-R(*GP*GP*UP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3') Authors: Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. Deposit date: 2014-07-18 Release date: 2014-08-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs. J.Am.Chem.Soc., 136, 2014
4U47	Octameric RNA duplex soaked in terbium(III)chloride Descriptor: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), TERBIUM(III) ION Authors: Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O. Deposit date: 2014-07-23 Release date: 2015-08-05 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.952 Å) Cite: The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations. Int J Mol Sci, 17, 2016
4U3P	Octameric RNA duplex co-crystallized with strontium(II)chloride Descriptor: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), STRONTIUM ION Authors: Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O. Deposit date: 2014-07-22 Release date: 2015-07-29 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.866 Å) Cite: The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations. Int J Mol Sci, 17, 2016
5M3F	Yeast RNA polymerase I elongation complex at 3.8A Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Neyer, S, Kunz, M, Geiss, C, Hantsche, M, Hodirnau, V.-V, Seybert, A, Engel, C, Scheffer, M.P, Cramer, P, Frangakis, A.S. Deposit date: 2016-10-14 Release date: 2016-11-23 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature, 540, 2016
7S7B	Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ... Authors: Puno, M.R, Lima, C.D. Deposit date: 2021-09-15 Release date: 2022-06-15 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (4.06 Å) Cite: Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
7S7C	Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2) Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ... Authors: Puno, M.R, Lima, C.D. Deposit date: 2021-09-15 Release date: 2022-06-15 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
1ANR	CIS-ACTING RNA REGULATORY ELEMENT (HIV-1 TAR), NMR, 20 STRUCTURES Descriptor: RNA REGULATORY ELEMENT TAR Authors: Aboul-Ela, F, Varani, G, Karn, J. Deposit date: 1996-07-06 Release date: 1997-01-11 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge. Nucleic Acids Res., 24, 1996
7AE1	Cryo-EM structure of human RNA Polymerase III elongation complex 1 Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. Deposit date: 2020-09-17 Release date: 2021-02-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7AE3	Cryo-EM structure of human RNA Polymerase III elongation complex 3 Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. Deposit date: 2020-09-17 Release date: 2021-02-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7AEA	Cryo-EM structure of human RNA Polymerase III elongation complex 2 Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. Deposit date: 2020-09-17 Release date: 2021-02-03 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
5LWJ	Solution NMR structure of the GTP binding Class II RNA aptamer-ligand-complex containing a protonated adenine nucleotide with a highly shifted pKa. Descriptor: GTP Class II RNA (34-MER), GUANOSINE-5'-TRIPHOSPHATE Authors: Wolter, A.C, Weickhmann, A.K, Nasiri, A.H, Hantke, K, Ohlenschlaeger, O, Wunderlich, C.H, Kreutz, C, Duchardt-Ferner, E, Woehnert, J. Deposit date: 2016-09-17 Release date: 2016-12-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: A Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer. Angew. Chem. Int. Ed. Engl., 56, 2017
7AOE	Schizosaccharomyces pombe RNA polymerase I (elongation complex) Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit rpa1, DNA-directed RNA polymerase I subunit rpa14, ... Authors: Heiss, F, Daiss, J, Becker, P, Engel, C. Deposit date: 2020-10-14 Release date: 2021-02-24 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Conserved strategies of RNA polymerase I hibernation and activation. Nat Commun, 12, 2021
1A9N	CRYSTAL STRUCTURE OF THE SPLICEOSOMAL U2B''-U2A' PROTEIN COMPLEX BOUND TO A FRAGMENT OF U2 SMALL NUCLEAR RNA Descriptor: RNA (5'-R(*CP*CP*UP*GP*GP*UP*AP*UP*UP*GP*CP*AP*GP*UP*AP*CP*CP*UP*CP*CP*AP*GP* GP*U)-3'), SPLICEOSOMAL U2B'', U2A' Authors: Price, S.R, Evans, P.R, Nagai, K. Deposit date: 1998-04-08 Release date: 1998-09-23 Last modified: 2021-11-03 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA. Nature, 394, 1998
6H67	Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. Deposit date: 2018-07-26 Release date: 2018-08-29 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis of RNA polymerase I stalling at UV light-induced DNA damage. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6H68	Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) with fully-ordered A49 Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. Deposit date: 2018-07-26 Release date: 2018-08-29 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structural basis of RNA polymerase I stalling at UV light-induced DNA damage. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HKO	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-07 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6HLR	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6HLQ	Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
7QTN	Duplex RNA containing Xanthosine-Cytosine base pairs Descriptor: RNA (5'-R(*GP*GP*UP*AP*(RY)P*UP*GP*CP*GP*(XAN)P*UP*AP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*AP*CP*UP*GP*CP*GP*(XAM)P*UP*AP*CP*C)-3') Authors: Ennifar, E, Micura, R. Deposit date: 2022-01-14 Release date: 2023-01-25 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA. Nucleic Acids Res., 50, 2022

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