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8UKU	RNA polymerase II elongation complex with Fapy-dG lesion with CMP added Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Hou, P, Oh, J, Wang, D. Deposit date: 2023-10-15 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
1ANR	CIS-ACTING RNA REGULATORY ELEMENT (HIV-1 TAR), NMR, 20 STRUCTURES Descriptor: RNA REGULATORY ELEMENT TAR Authors: Aboul-Ela, F, Varani, G, Karn, J. Deposit date: 1996-07-06 Release date: 1997-01-11 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge. Nucleic Acids Res., 24, 1996
1A9N	CRYSTAL STRUCTURE OF THE SPLICEOSOMAL U2B''-U2A' PROTEIN COMPLEX BOUND TO A FRAGMENT OF U2 SMALL NUCLEAR RNA Descriptor: RNA (5'-R(*CP*CP*UP*GP*GP*UP*AP*UP*UP*GP*CP*AP*GP*UP*AP*CP*CP*UP*CP*CP*AP*GP* GP*U)-3'), SPLICEOSOMAL U2B'', U2A' Authors: Price, S.R, Evans, P.R, Nagai, K. Deposit date: 1998-04-08 Release date: 1998-09-23 Last modified: 2021-11-03 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA. Nature, 394, 1998
1BVJ	HIV-1 RNA A-RICH HAIRPIN LOOP Descriptor: RNA (5'-R(P*GP*GP*CP*GP*AP*CP*GP*GP*UP*GP*UP*AP*AP*AP*AP*AP*UP*CP*UP*CP*GP*CP* C)-3') Authors: Puglisi, E.V, Puglisi, J.D. Deposit date: 1998-08-31 Release date: 1998-12-09 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: HIV-1 A-rich RNA loop mimics the tRNA anticodon structure. Nat.Struct.Biol., 5, 1998
1C4L	SOLUTION STRUCTURE OF AN RNA DUPLEX INCLUDING A C-U BASE-PAIR Descriptor: RNA (5'-R(*CP*CP*UP*GP*CP*GP*UP*CP*G)-3'), RNA (5'-R(*CP*GP*AP*CP*UP*CP*AP*GP*G)-3') Authors: Tanaka, Y, Kojima, C, Yamazaki, T, Kodama, T.S, Yasuno, K, Miyashita, S, Ono, A.M, Ono, A.S, Kainosho, M, Kyogoku, Y. Deposit date: 1999-08-30 Release date: 2000-08-09 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of an RNA duplex including a C-U base pair. Biochemistry, 39, 2000
1AL5	A-TRACT RNA DODECAMER, NMR, 12 STRUCTURES Descriptor: RNA (5'-R(*CP*GP*CP*AP*AP*AP*UP*UP*UP*GP*CP*G)-3') Authors: Conte, M.R, Conn, G.L, Brown, T, Lane, A.N. Deposit date: 1997-06-11 Release date: 1997-12-17 Last modified: 2021-11-03 Method: SOLUTION NMR Cite: Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: comparison with the DNA analogue d(CGCAAATTTGCG)2. Nucleic Acids Res., 25, 1997
157D	CRYSTAL AND MOLECULAR STRUCTURE OF R(CGCGAAUUAGCG): AN RNA DUPLEX CONTAINING TWO G(ANTI).A(ANTI) BASE-PAIRS Descriptor: RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3') Authors: Leonard, G.A, McAuley-Hecht, K.E, Ebel, S, Lough, D.M, Brown, T, Hunter, W.N. Deposit date: 1994-02-01 Release date: 1994-05-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal and molecular structure of r(CGCGAAUUAGCG): an RNA duplex containing two G(anti).A(anti) base pairs. Structure, 2, 1994
8TNS	Solution structure of poly(UG) RNA (GU)12 G-quadruplex Descriptor: RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*U)-3') Authors: Escobar, C.A, Petersen, R, Butcher, S.E. Deposit date: 2023-08-02 Release date: 2023-11-15 Last modified: 2023-11-22 Method: SOLUTION NMR, SOLUTION SCATTERING Cite: Solution Structure of Poly(UG) RNA. J.Mol.Biol., 435, 2023
8SX6	RNA duplex bound with GMP and AMP monomers Descriptor: ADENOSINE MONOPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... Authors: Zhang, W, Dantsu, Y. Deposit date: 2023-05-19 Release date: 2023-05-31 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Insight into the structures of unusual base pairs in RNA complexes containing a primer/template/adenosine ligand. Rsc Chem Biol, 4, 2023
8SXL	RNA UU template binding to AMP monomer Descriptor: ADENOSINE MONOPHOSPHATE, RNA (5'-R(*(TLN)P*(TLN)P*(LCA)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*U)-3') Authors: Zhang, W, Dantsu, Y. Deposit date: 2023-05-22 Release date: 2023-05-31 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Insight into the structures of unusual base pairs in RNA complexes containing a primer/template/adenosine ligand. Rsc Chem Biol, 4, 2023
8SWG	RNA duplex bound with GpppA dinucleotide ligand Descriptor: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G*(GA3))-3') Authors: Zhang, W, Dantsu, Y. Deposit date: 2023-05-18 Release date: 2023-05-31 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Insight into the structures of unusual base pairs in RNA complexes containing a primer/template/adenosine ligand. Rsc Chem Biol, 4, 2023
5G5L	RNA polymerase I-Rrn3 complex at 4.8 A resolution Descriptor: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... Authors: Engel, C, Plitzko, J, Cramer, P. Deposit date: 2016-05-26 Release date: 2016-07-27 Last modified: 2018-10-24 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: RNA Polymerase I-Rrn3 Complex at 4.8 A Resolution Nat.Commun., 7, 2016
5M3F	Yeast RNA polymerase I elongation complex at 3.8A Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Neyer, S, Kunz, M, Geiss, C, Hantsche, M, Hodirnau, V.-V, Seybert, A, Engel, C, Scheffer, M.P, Cramer, P, Frangakis, A.S. Deposit date: 2016-10-14 Release date: 2016-11-23 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature, 540, 2016
8SKQ	RNA oligonucleotide containing an alpha-(L)-threofuranosyl nucleic acid (TNA) Descriptor: TNA-containing RNA oligonucleotide Authors: Harp, J.M, Egli, M. Deposit date: 2023-04-20 Release date: 2024-02-14 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Shorter Is Better: The alpha-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs. J.Am.Chem.Soc., 145, 2023
5N5C	NMR solution structure of the TSL2 RNA hairpin Descriptor: RNA (19-MER) Authors: Garcia-Lopez, A, Wacker, A, Tessaro, F, Jonker, H.R.A, Richter, C, Comte, A, Berntenis, N, Schmucki, R, Hatje, K, Sciarra, D, Konieczny, P, Fournet, G, Faustino, I, Orozco, M, Artero, R, Goekjian, P, Metzger, F, Ebeling, M, Joseph, B, Schwalbe, H, Scapozza, L. Deposit date: 2017-02-13 Release date: 2018-03-14 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes. Nat Commun, 9, 2018
5LWJ	Solution NMR structure of the GTP binding Class II RNA aptamer-ligand-complex containing a protonated adenine nucleotide with a highly shifted pKa. Descriptor: GTP Class II RNA (34-MER), GUANOSINE-5'-TRIPHOSPHATE Authors: Wolter, A.C, Weickhmann, A.K, Nasiri, A.H, Hantke, K, Ohlenschlaeger, O, Wunderlich, C.H, Kreutz, C, Duchardt-Ferner, E, Woehnert, J. Deposit date: 2016-09-17 Release date: 2016-12-14 Last modified: 2019-09-18 Method: SOLUTION NMR Cite: A Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer. Angew. Chem. Int. Ed. Engl., 56, 2017
7AE1	Cryo-EM structure of human RNA Polymerase III elongation complex 1 Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. Deposit date: 2020-09-17 Release date: 2021-02-03 Last modified: 2021-02-17 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7AE3	Cryo-EM structure of human RNA Polymerase III elongation complex 3 Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. Deposit date: 2020-09-17 Release date: 2021-02-03 Last modified: 2021-02-17 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7AEA	Cryo-EM structure of human RNA Polymerase III elongation complex 2 Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. Deposit date: 2020-09-17 Release date: 2021-02-03 Last modified: 2021-02-17 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7S7C	Human Nuclear Exosome Targeting (NEXT) complex bound to RNA (substrate 2) Descriptor: Exosome RNA helicase MTR4, RNA (30-MER), RNA-binding protein 7, ... Authors: Puno, M.R, Lima, C.D. Deposit date: 2021-09-15 Release date: 2022-06-15 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
7S7B	Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) Descriptor: Exosome RNA helicase MTR4, RNA (46-MER), RNA-binding protein 7, ... Authors: Puno, M.R, Lima, C.D. Deposit date: 2021-09-15 Release date: 2022-06-15 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (4.06 Å) Cite: Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell, 185, 2022
6UPZ	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.1 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UPY	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ3	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.47 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UPX	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020

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