PDB: 102 件ウェブページステータス検索Chemie searchBIRD

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5RZD	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z198194394 分子名称: 1,2-ETHANEDIOL, 4-(4-fluorophenyl)piperazine-1-carboxamide, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
5RZN	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1745658474 分子名称: 1,2-ETHANEDIOL, 2-(trifluoromethyl)pyrimidine-5-carboxamide, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
5RZK	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1266823232 分子名称: (1S)-1-(2,4-dimethyl-1,3-thiazol-5-yl)-N-methylethan-1-amine, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
8CIR	The FERM domain of human moesin with a bound peptide identified by phage display 分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ... 著者 Bradshaw, W.J, Katis, V.L, Leisner, T.M, Fairhead, M, Bountra, C, von Delft, F, Pearce, K.H, Brennan, P.E. 登録日 2023-02-10 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
6T36	Crystal structure of the PTPN3 PDZ domain bound to the HBV core protein C-terminal peptide 分子名称: BROMIDE ION, Capsid protein, Tyrosine-protein phosphatase non-receptor type 3 著者 Genera, M, Mechaly, A, Haouz, A, Caillet-Saguy, C. 登録日 2019-10-10 公開日 2021-01-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein. Sci Rep, 11, 2021
5RYR	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z104584152 分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Isoform 2 of Band 4.1-like protein 3, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
5RZH	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434890 分子名称: 1,2-ETHANEDIOL, 4-methyl-N-phenylpiperazine-1-carboxamide, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
5RZQ	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z100642432 分子名称: 1,2-ETHANEDIOL, 2-bromo-4-fluoro-N,N-dimethylbenzamide, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
5RYN	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z1545312521 分子名称: (2S)-N-(3-chloro-2-methylphenyl)oxolane-2-carboxamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
5RZA	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z729352906 分子名称: 1,2-ETHANEDIOL, 2-[(3-fluorophenyl)methyl]-1lambda~6~,2-thiazolidine-1,1-dione, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
1EF1	CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX 分子名称: MOESIN, SULFATE ION 著者 Pearson, M.A, Reczek, D, Bretscher, A, Karplus, P.A. 登録日 2000-02-04 公開日 2000-05-10 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell(Cambridge,Mass.), 101, 2000
4RM8	Crystal structure of human ezrin in space group P21 分子名称: Ezrin 著者 Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-20 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
5RZO	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z2856434925 分子名称: 1,2-ETHANEDIOL, 4-[(5-chloro-1,2,3-thiadiazol-4-yl)methyl]morpholine, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
6D21	Crystal structure of the FERM domain of zebrafish FARP2 分子名称: FERM, RhoGEF and pleckstrin domain protein 2 著者 Kuo, Y.C, Zhang, X. 登録日 2018-04-12 公開日 2018-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
4RM9	Crystal structure of human ezrin in space group C2221 分子名称: Ezrin 著者 Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. 登録日 2014-10-21 公開日 2015-12-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
2HE7	FERM domain of EPB41L3 (DAL-1) 分子名称: Band 4.1-like protein 3 著者 Hallberg, B.M, Busam, R.D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Schiavone, L.H, Johansson, I, Hogbom, M, Karlberg, T, Kotenyova, T, Nilvebrandt, J, Norberg, P, Stenmark, P, Nordlund, P, Nilsson-ehle, P, Nyman, T, Ogg, D, Sagemark, J, Sundstrom, M, Uppenberg, J, Van den berg, S, Weigelt, J, Persson, C, Thorsell, A.G, Structural Genomics Consortium (SGC) 登録日 2006-06-21 公開日 2006-07-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B). J.Biol.Chem., 286, 2011
5RZI	EPB41L3 PanDDA analysis group deposition -- Crystal Structure of the FERM domain of human EPB41L3 in complex with Z48852953 分子名称: 1,2-ETHANEDIOL, 4-methyl-N-{[(2R)-oxolan-2-yl]methyl}-1,3-thiazol-2-amine, DIMETHYL SULFOXIDE, ... 著者 Bradshaw, W.J, Katis, V.L, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. 登録日 2020-10-30 公開日 2020-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 EPB41L3 PanDDA analysis group deposition To Be Published
2I1J	Moesin from Spodoptera frugiperda at 2.1 angstroms resolution 分子名称: CHLORIDE ION, GLYCEROL, Moesin, ... 著者 Li, Q, Nance, M.R, Tesmer, J.J.G. 登録日 2006-08-14 公開日 2006-12-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain. J.Mol.Biol., 365, 2007
8GVL	PTPN21 FERM 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Tyrosine-protein phosphatase non-receptor type 21 著者 Chen, L, Zheng, Y.Y, Zhou, C. 登録日 2022-09-15 公開日 2023-09-20 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity. Sci Adv, 10, 2024
2ZPY	Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide 分子名称: CD44 antigen, Radixin 著者 Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T. 登録日 2008-07-31 公開日 2008-08-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for CD44 recognition by ERM proteins J.Biol.Chem., 283, 2008
6TXS	The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide 分子名称: CD44 antigen, Moesin 著者 Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2020-01-14 公開日 2020-01-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
4ZRJ	Structure of Merlin-FERM and CTD 分子名称: GLYCEROL, Merlin 著者 Lin, Z, Li, F, Long, J, Shen, Y. 登録日 2015-05-12 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway Cell Res., 25, 2015
1NI2	Structure of the active FERM domain of Ezrin 分子名称: Ezrin 著者 Smith, W.J, Nassar, N, Bretscher, A.P, Cerione, R.A, Karplus, P.A. 登録日 2002-12-20 公開日 2003-02-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS. J.Biol.Chem., 278, 2003
3BIN	Structure of the DAL-1 and TSLC1 (372-383) complex 分子名称: Band 4.1-like protein 3, Cell adhesion molecule 1 著者 Busam, R.D, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Berglund, H, Persson, C, Hallberg, B.M. 登録日 2007-11-30 公開日 2008-01-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B) J.Biol.Chem., 286, 2011
3WA0	Crystal structure of merlin complexed with DCAF1/VprBP 分子名称: Merlin, Protein VPRBP 著者 Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T. 登録日 2013-04-20 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function. Genes Cells, 19, 2014

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