1HZP
| Crystal Structure of the Myobacterium Tuberculosis Beta-Ketoacyl-Acyl Carrier Protein Synthase III | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III, GLYCEROL, LAURIC ACID | Authors: | Scarsdale, J.N, Kazanina, G, He, X, Reynolds, K.A, Wright, H.T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2001-01-25 | Release date: | 2001-06-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III J.Biol.Chem., 276, 2001
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3S3L
| Crystal Structure of CerJ from Streptomyces tendae | Descriptor: | ACETATE ION, CHLORIDE ION, CerJ | Authors: | Zocher, G, Hertweck, C, Bretschneider, T, Stehle, T. | Deposit date: | 2011-05-18 | Release date: | 2011-12-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat.Chem.Biol., 8, 2011
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3T5Y
| Crystal structure of CerJ from Streptomyces tendae - malonic acid covalently linked to the catalytic Cystein C116 | Descriptor: | ACETATE ION, CerJ | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | Deposit date: | 2011-07-28 | Release date: | 2011-12-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat.Chem.Biol., 8, 2011
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3T8E
| Crystal structure of CerJ from Streptomyces tendae soaked with CerviK | Descriptor: | ACETATE ION, CerJ | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | Deposit date: | 2011-08-01 | Release date: | 2011-12-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat.Chem.Biol., 8, 2011
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1HNJ
| CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III + MALONYL-COA | Descriptor: | BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, MALONYL-COENZYME A, PHOSPHATE ION | Authors: | Qiu, X, Janson, C.A, Smith, W.W, Head, M, Lonsdale, J, Konstantinidis, A.K. | Deposit date: | 2000-12-07 | Release date: | 2000-12-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Refined structures of beta-ketoacyl-acyl carrier protein synthase III. J.Mol.Biol., 307, 2001
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3T6S
| Crystal structure of CerJ from Streptomyces tendae in Complex with CoA | Descriptor: | COENZYME A, CerJ | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | Deposit date: | 2011-07-29 | Release date: | 2011-12-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat.Chem.Biol., 8, 2011
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1HN9
| CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III | Descriptor: | BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, PHOSPHATE ION | Authors: | Qiu, X, Janson, C.A, Konstantinidis, A.K, Nwagwu, S, Silverman, C, Smith, W.W, Khandekar, S.K, Lonsdale, J, Abdel-Meguid, S.S. | Deposit date: | 2000-12-07 | Release date: | 2000-12-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis. J.Biol.Chem., 274, 1999
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1HNH
| CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III + DEGRADED FORM OF ACETYL-COA | Descriptor: | BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, COENZYME A | Authors: | Qiu, X, Janson, C.A, Smith, W.W, Head, M, Lonsdale, J, Konstantinidis, A.K. | Deposit date: | 2000-12-07 | Release date: | 2000-12-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Refined structures of beta-ketoacyl-acyl carrier protein synthase III. J.Mol.Biol., 307, 2001
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1HND
| CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III-COA COMPLEX | Descriptor: | BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, COENZYME A | Authors: | Qiu, X, Janson, C.A, Smith, W.W, Head, M, Lonsdale, J, Konstantinidis, A.K. | Deposit date: | 2000-12-07 | Release date: | 2000-12-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Refined structures of beta-ketoacyl-acyl carrier protein synthase III. J.Mol.Biol., 307, 2001
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3S21
| Crystal structure of cerulenin bound Xanthomonas campestri OleA (co-crystal) | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Goblirsch, B.R, Wilmot, C.M. | Deposit date: | 2011-05-16 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7001 Å) | Cite: | Crystal Structures of Xanthomonas campestris OleA Reveal Features That Promote Head-to-Head Condensation of Two Long-Chain Fatty Acids. Biochemistry, 51, 2012
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3S23
| Crystal structure of cerulenin bound Xanthomonas campestri oleA (co-crystal) Xe Derivative | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Goblirsch, B.R, Wilmot, C.M. | Deposit date: | 2011-05-16 | Release date: | 2012-05-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9484 Å) | Cite: | Crystal Structures of Xanthomonas campestris OleA Reveal Features That Promote Head-to-Head Condensation of Two Long-Chain Fatty Acids. Biochemistry, 51, 2012
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2QO0
| Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and 11-(decyldithiocarbonyloxy)-undecanoic acid | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, DECANE-1-THIOL | Authors: | Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. | Deposit date: | 2007-07-19 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
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2QO1
| 2.6 Angstrom Crystal Structure of the Complex Between 11-(decyldithiocarbonyloxy)-undecanoic acid and Mycobacterium Tuberculosis FabH. | Descriptor: | 11-[(MERCAPTOCARBONYL)OXY]UNDECANOIC ACID, 3-oxoacyl-[acyl-carrier-protein] synthase 3, DECANE-1-THIOL | Authors: | Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. | Deposit date: | 2007-07-19 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
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5YOA
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5VXD
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5VXE
| Crystal structure of Xanthomonas campestris OleA E117A bound with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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5VXG
| Crystal structure of Xanthomonas campestris OleA E117Q bound with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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5V0P
| Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2, OCTANOYL-COENZYME A, SODIUM ION | Authors: | Hou, J, Zheng, H, Cooper, D.R, Grabowski, M, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-28 | Release date: | 2017-03-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA To Be Published
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5VXH
| Crystal structure of Xanthomonas campestris OleA E117D | Descriptor: | 3-oxoacyl-[ACP] synthase III, GLYCEROL, PHOSPHATE ION | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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5VXF
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5VXI
| Crystal structure of Xanthomonas campestris OleA E117D bound with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Wilmot, C.M. | Deposit date: | 2017-05-23 | Release date: | 2017-10-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | OleA Glu117 is key to condensation of two fatty-acyl coenzyme A substrates in long-chain olefin biosynthesis. Biochem. J., 474, 2017
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5YZU
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6B2U
| Crystal structure of Xanthomonas campestris OleA H285N with Cerulenin | Descriptor: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | Authors: | Jensen, M.R, Goblirsch, B.R, Esler, M.A, Christenson, J.K, Mohamed, F.A, Wackett, L.P, Wilmot, C.M. | Deposit date: | 2017-09-20 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | The role of OleA His285 in substrate coordination of long-chain acyl-CoA To be published
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2QNY
| Crystal structure of the complex between the A246F mutant of mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and SS-(2-hydroxyethyl) O-decyl ester carbono(dithioperoxoic) acid | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 3, BETA-MERCAPTOETHANOL, DECYL FORMATE | Authors: | Sachdeva, S, Musayev, F, Alhamadsheh, M, Scarsdale, J.N, Wright, H.T, Reynolds, K.A. | Deposit date: | 2007-07-19 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH Chem.Biol., 15, 2008
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2X3E
| Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase III, FabH from Pseudomonas aeruginosa PAO1 | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3 | Authors: | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | Deposit date: | 2010-01-24 | Release date: | 2010-07-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genomics, 11, 2010
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