PDB: 62 件ウェブページステータス検索Chemie searchBIRD

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3VKG	X-ray structure of an MTBD truncation mutant of dynein motor domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dynein heavy chain, cytoplasmic, ... 著者 Kon, T, Oyama, T, Shimo-Kon, R, Suto, K, Kurisu, G. 登録日 2011-11-16 公開日 2012-03-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The 2.8 A crystal structure of the dynein motor domain Nature, 484, 2012
8FD6	Engineered human dynein motor domain in the microtubule-unbound state in the buffer containing ATP-Vi 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... 著者 Ton, W, Wang, Y, Chai, P. 登録日 2022-12-02 公開日 2023-06-21 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
7MGM	Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Lahiri, I, Reimer, J.M, Leschziner, A.E. 登録日 2021-04-12 公開日 2022-01-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for cytoplasmic dynein-1 regulation by Lis1. Elife, 11, 2022
8GLV	96-nm repeat unit of doublet microtubules from Chlamydomonas reinhardtii flagella 分子名称: 28 kDa inner dynein arm light chain, axonemal, AAA+ ATPase domain-containing protein, ... 著者 Walton, T, Brown, A. 登録日 2023-03-23 公開日 2023-05-31 最終更新日 2023-06-28 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Axonemal structures reveal mechanoregulatory and disease mechanisms. Nature, 618, 2023
8FDT	Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... 著者 Ton, W, Wang, Y, Chai, P. 登録日 2022-12-04 公開日 2023-06-21 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
8FDU	Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, Platelet-activating factor acetylhydrolase IB subunit beta,Platelet-activating factor acetylhydrolase IB subunit beta,human LIS1 protein with a SNAP tag 著者 Ton, W, Wang, Y, Chai, P. 登録日 2022-12-04 公開日 2023-06-21 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
4AKG	Dynein Motor Domain - ATP complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, ... 著者 Schmidt, H, Gleave, E.S, Carter, A.P. 登録日 2012-02-22 公開日 2012-03-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
7Z8I	The barbed end complex of dynactin bound to BICDR1 and the cytoplasmic dynein tails (A2, B1, B2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, ... 著者 Chaaban, S, Carter, A.P. 登録日 2022-03-17 公開日 2022-08-17 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
7KZO	Outer dynein arm docking complex bound to doublet microtubules from C. reinhardtii 分子名称: Dynein gamma chain, flagellar outer arm, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Walton, T, Wu, H, Brown, A.B. 登録日 2020-12-10 公開日 2021-01-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of a microtubule-bound axonemal dynein. Nat Commun, 12, 2021
8FCY	Engineered human dynein motor domain in microtubule-bound state 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase 著者 Ton, W, Wang, Y, Chai, P. 登録日 2022-12-01 公開日 2023-06-21 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
4AI6	Dynein Motor Domain - ADP complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, ... 著者 Schmidt, H, Gleave, E.S, Carter, A.P. 登録日 2012-02-08 公開日 2012-03-14 最終更新日 2017-03-15 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
4RH7	Crystal structure of human cytoplasmic dynein 2 motor domain in complex with ADP.Vi 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ... 著者 Schmidt, H, Zalyte, R, Urnavicius, L, Carter, A.P. 登録日 2014-10-01 公開日 2014-12-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.41 Å) 主引用文献 Structure of human cytoplasmic dynein-2 primed for its power stroke. Nature, 518, 2015
7Z8H	Cytoplasmic dynein-1 motor domain AAA1, AAA2, and AAA3 subunits 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... 著者 Chaaban, S, Carter, A.P. 登録日 2022-03-17 公開日 2022-07-27 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
7MI3	Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4 分子名称: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ... 著者 Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. 登録日 2021-04-16 公開日 2021-05-26 最終更新日 2021-11-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
7K58	Structure of outer-arm dyneins bound to microtubule with microtubule binding state 1(MTBS-1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... 著者 Qinhui, R, Kai, Z. 登録日 2020-09-16 公開日 2021-09-29 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat.Struct.Mol.Biol., 28, 2021
7Z8G	Cytoplasmic dynein-1 motor domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... 著者 Chaaban, S, Carter, A.P. 登録日 2022-03-17 公開日 2022-07-27 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
4W8F	Crystal structure of the dynein motor domain in the AMPPNP-bound state 分子名称: Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D. 登録日 2014-08-24 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.541 Å) 主引用文献 Allosteric communication in the Dynein motor domain. Cell, 159, 2014
8E00	Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... 著者 Reimer, J.M, Lahiri, I, Leschziner, A.E. 登録日 2022-08-08 公開日 2023-08-30 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nat.Struct.Mol.Biol., 30, 2023
4AKH	Dynein Motor Domain - AMPPNP complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ... 著者 Schmidt, H, Gleave, E.S, Carter, A.P. 登録日 2012-02-22 公開日 2012-03-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
7MI8	Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5 分子名称: Fusion protein of Dynein and Endolysin 著者 Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M. 登録日 2021-04-16 公開日 2021-05-26 最終更新日 2021-11-03 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Targeting allostery in the Dynein motor domain with small molecule inhibitors. Cell Chem Biol, 28, 2021
4AKI	Dynein Motor Domain - LuAc derivative 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ... 著者 Schmidt, H, Gleave, E.S, Carter, A.P. 登録日 2012-02-22 公開日 2012-03-14 最終更新日 2017-03-15 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
5NUG	Motor domains from human cytoplasmic dynein-1 in the phi-particle conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... 著者 Zhang, K, Foster, H.E, Carter, A.P. 登録日 2017-04-30 公開日 2017-06-28 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
8PR2	Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI 分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... 著者 Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. 登録日 2023-07-12 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
8PQY	Cytoplasmic dynein-1 motor domain bound to LIS1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... 著者 Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. 登録日 2023-07-12 公開日 2024-03-27 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
3VKH	X-ray structure of a functional full-length dynein motor domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dynein heavy chain, cytoplasmic 著者 Kon, T, Oyama, T, Shimo-Kon, R, Suto, K, Kurisu, G. 登録日 2011-11-16 公開日 2012-03-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 The 2.8 A crystal structure of the dynein motor domain Nature, 484, 2012

 

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