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8B0X
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BU of 8b0x by Molmil
Translating 70S ribosome in the unrotated state (P and E, tRNAs)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fromm, S.A, O'Connor, K.M, Purdy, M, Bhatt, P.R, Loughran, G, Atkins, J.F, Jomaa, A, Mattei, S.
Deposit date:2022-09-08
Release date:2022-11-30
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (1.55 Å)
Cite:The translating bacterial ribosome at 1.55 angstrom resolution generated by cryo-EM imaging services.
Nat Commun, 14, 2023
8GLP
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BU of 8glp by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C.
Deposit date:2023-03-22
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.67 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8CGJ
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BU of 8cgj by Molmil
Streptomycin bound to the 30S body
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N.
Deposit date:2023-02-05
Release date:2023-07-26
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (1.79 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CF1
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BU of 8cf1 by Molmil
Tetracycline bound to the 30S head
Descriptor: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N.
Deposit date:2023-02-02
Release date:2023-07-26
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (1.82 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8FTO
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BU of 8fto by Molmil
E. coli 70S ribosome with an improved MS2 tag inserted in H98
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nissley, A.J, Cate, J.H.D.
Deposit date:2023-01-12
Release date:2023-08-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.85 Å)
Cite:Interactions between terminal ribosomal RNA helices stabilize the E. coli large ribosomal subunit.
Rna, 29, 2023
1WF3
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BU of 1wf3 by Molmil
Crystal structure of GTP-binding protein TT1341 from Thermus thermophilus HB8
Descriptor: GLYCEROL, GTP-binding protein, MAGNESIUM ION, ...
Authors:Kawazoe, M, Hori-Takemoto, C, Kaminishi, T, Sekine, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-25
Release date:2004-11-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of GTP-binding protein TT1341 from Thermus thermophilus HB8
To be Published
8CGI
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BU of 8cgi by Molmil
Pentacycline TP038 bound to the 30S head
Descriptor: 16S rRNA, 30S ribosomal protein S7, Large ribosomal subunit protein bL31A, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
Deposit date:2023-02-04
Release date:2023-07-26
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (1.89 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
3IEV
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BU of 3iev by Molmil
Crystal Structure of ERA in Complex with MgGNP and the 3' End of 16S rRNA
Descriptor: 5'-R(P*AP*UP*CP*AP*CP*CP*UP*CP*CP*UP*UP*A)-3', GTP-binding protein era, MAGNESIUM ION, ...
Authors:Tu, C, Ji, X.
Deposit date:2009-07-23
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of ERA in complex with the 3' end of 16S rRNA: implications for ribosome biogenesis
Proc.Natl.Acad.Sci.USA, 106, 2009
8AYE
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BU of 8aye by Molmil
E. coli 70S ribosome bound to thermorubin and fMet-tRNA
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Sanyal, S, Parajuli, N.P, Emmerich, A.G.
Deposit date:2022-09-02
Release date:2023-03-01
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (1.96 Å)
Cite:Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria.
Nat Commun, 14, 2023
8CCS
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BU of 8ccs by Molmil
80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-01-27
Release date:2023-09-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (1.97 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
7K00
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BU of 7k00 by Molmil
Structure of the Bacterial Ribosome at 2 Angstrom Resolution
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Watson, Z.L, Ward, F.R, Meheust, R, Ad, O, Schepartz, A, Banfield, J.F, Cate, J.H.D.
Deposit date:2020-09-02
Release date:2020-09-23
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:Structure of the bacterial ribosome at 2 angstrom resolution.
Elife, 9, 2020
8QOA
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BU of 8qoa by Molmil
Structure of SecM-stalled Escherichia coli 70S ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ...
Authors:Gersteuer, F, Morici, M, Wilson, D.N.
Deposit date:2023-09-28
Release date:2024-03-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2 Å)
Cite:The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome.
Nat Commun, 15, 2024
2CXC
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BU of 2cxc by Molmil
Crystal structure of archaeal transcription termination factor NusA
Descriptor: NusA
Authors:Shibata, R, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-28
Release date:2005-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA
Biochem.Biophys.Res.Commun., 355, 2007
8G6W
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BU of 8g6w by Molmil
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.02 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8BIM
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BU of 8bim by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAm6A codon in the A-site
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-11-02
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.04 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BIL
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BU of 8bil by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAA codon in the A-site.
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-11-02
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.04 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8CDR
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BU of 8cdr by Molmil
Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-01-31
Release date:2023-09-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.04 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
3R9W
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BU of 3r9w by Molmil
Crystal structure of Era in complex with MgGDPNP and nucleotides 1506-1542 of 16S ribosomal RNA
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, CALCIUM ION, ...
Authors:Tu, C, Ji, X.
Deposit date:2011-03-26
Release date:2011-06-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3' end of 16S rRNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
8CEH
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BU of 8ceh by Molmil
Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
Deposit date:2023-02-01
Release date:2023-09-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.05 Å)
Cite:mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8CA7
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BU of 8ca7 by Molmil
Omadacycline and spectinomycin bound to the 30S ribosomal subunit head
Descriptor: 16S rRNA, 30S ribosomal protein S7, MAGNESIUM ION, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Wilson, D.N.
Deposit date:2023-01-24
Release date:2023-08-02
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (2.06 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CAI
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BU of 8cai by Molmil
Streptomycin and Hygromycin B bound to the 30S body
Descriptor: 16S rRNA, 30S ribosomal protein S16, 30S ribosomal protein S2, ...
Authors:Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
Deposit date:2023-01-24
Release date:2023-07-26
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.08 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8EMM
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BU of 8emm by Molmil
Composite 70S ribosome structure for "Atomistic simulations of the E. coli ribosome provide selection criteria for translationally active substrates
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Watson, Z.L, Cate, J.H.D.
Deposit date:2022-09-28
Release date:2023-05-31
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates.
Nat.Chem., 15, 2023
4YBB
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BU of 4ybb by Molmil
High-resolution structure of the Escherichia coli ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D.
Deposit date:2015-02-18
Release date:2015-03-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-resolution structure of the Escherichia coli ribosome.
Nat.Struct.Mol.Biol., 22, 2015
8BGE
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BU of 8bge by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and AAm6A mRNA codon in the A-site after uncompleted di-peptide formation
Descriptor: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
Authors:Koziej, L, Glatt, S.
Deposit date:2022-10-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.11 Å)
Cite:Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8CAZ
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BU of 8caz by Molmil
empty 30S head
Descriptor: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
Authors:Paternoga, H, Beckert, B, Wilson, D.N.
Deposit date:2023-01-24
Release date:2023-07-26
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (2.11 Å)
Cite:Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023

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數據於2024-04-24公開中

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