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1EE8
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CRYSTAL STRUCTURE OF MUTM (FPG) PROTEIN FROM THERMUS THERMOPHILUS HB8
分子名称: MUTM (FPG) PROTEIN, ZINC ION
著者Sugahara, M, Mikawa, T, Kumasaka, T, Yamamoto, M, Kato, R, Fukuyama, K, Inoue, Y, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2000-01-31
公開日2001-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8.
EMBO J., 19, 2000
1FFY
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INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN
分子名称: ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, ...
著者Silvian, L.F, Wang, J, Steitz, T.A.
登録日2000-07-26
公開日2000-08-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin.
Science, 285, 1999
1K3W
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Crystal structure of a trapped reaction intermediate of the DNA Repair Enzyme Endonuclease VIII with DNA
分子名称: 5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*GP*G)-3', Endonuclease VIII, ...
著者Golan, G, Zharkov, D.O, Gilboa, R, Fernandes, A.S, Kycia, J.H, Gerchman, S.E, Rieger, R.A, Grollman, A.P, Shoham, G.
登録日2001-10-04
公開日2002-10-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate.
EMBO J., 21, 2002
1K3X
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Crystal structure of a trapped reaction intermediate of the DNA repair enzyme Endonuclease VIII with Brominated-DNA
分子名称: 5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*(BRU)P*(BRU)P*CP*AP*(BRU)P*CP*CP*(BRU)P*GP*G)-3', Endonuclease VIII, ...
著者Golan, G, Zharkov, D.O, Gilboa, R, Fernandes, A.S, Kycia, J.H, Gerchman, S.E, Rieger, R.A, Grollman, A.P, Shoham, G.
登録日2001-10-04
公開日2002-10-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate.
EMBO J., 21, 2002
1K82
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Crystal structure of E.coli formamidopyrimidine-DNA glycosylase (Fpg) covalently trapped with DNA
分子名称: 5'-D(*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*CP*CP*TP*CP*CP*TP*GP*G)-3', ZINC ION, ...
著者Gilboa, R, Zharkov, D.O, Golan, G, Fernandes, A.S, Gerchman, S.E, Matz, E, Kycia, J.H, Grollman, A.P, Shoham, G.
登録日2001-10-22
公開日2002-06-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.
J.Biol.Chem., 277, 2002
1KFV
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Crystal Structure of Lactococcus lactis Formamido-pyrimidine DNA Glycosylase (alias Fpg or MutM) Non Covalently Bound to an AP Site Containing DNA.
分子名称: 5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*C)-3', 5'-D(*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*AP*G)-3', Formamido-pyrimidine DNA glycosylase, ...
著者Serre, L, Pereira de Jesus, K, Boiteux, S, Zelwer, C, Castaing, B.
登録日2001-11-23
公開日2002-06-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA.
EMBO J., 21, 2002
1L1T
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MutM (Fpg) Bound to Abasic-Site Containing DNA
分子名称: 5'-D(*AP*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
著者Fromme, J.C, Verdine, G.L.
登録日2002-02-19
公開日2002-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1L1Z
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MutM (Fpg) Covalent-DNA Intermediate
分子名称: 5'-D(*AP*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
著者Fromme, J.C, Verdine, G.L.
登録日2002-02-20
公開日2002-06-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1L2B
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MutM (Fpg) DNA End-Product Structure
分子名称: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*C*(AD2))-3', 5'-D(P*GP*TP*CP*TP*AP*CP*C)-3', ...
著者Fromme, J.C, Verdine, G.L.
登録日2002-02-20
公開日2002-06-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1L2C
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MutM (Fpg)-DNA Estranged Thymine Mismatch Recognition Complex
分子名称: 5'-D(*AP*G*GP*TP*AP*GP*AP*CP*TP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
著者Fromme, J.C, Verdine, G.L.
登録日2002-02-20
公開日2002-06-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM.
Nat.Struct.Biol., 9, 2002
1NNJ
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Crystal structure Complex between the Lactococcus lactis Fpg and an abasic site containing DNA
分子名称: 5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', Formamidopyrimidine-DNA glycosylase, ...
著者Serre, L, Pereira de Jesus, K, Boiteux, S, Zelwer, C, Castaing, B.
登録日2003-01-14
公開日2003-02-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1PJI
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Crystal structure of wild type Lactococcus lactis FPG complexed to a 1,3 propanediol containing DNA
分子名称: DNA (5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ...
著者Pereira, K, Serre, L, Zelwer, C, Castaing, B.
登録日2003-06-03
公開日2004-08-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1PJJ
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Complex between the Lactococcus lactis Fpg and an abasic site containing DNA.
分子名称: DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ...
著者Serre, L, Pereira de Jesus, K, Boiteux, S, Zelwer, C, Castaing, B.
登録日2003-06-03
公開日2004-06-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1PM5
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Crystal structure of wild type Lactococcus lactis Fpg complexed to a tetrahydrofuran containing DNA
分子名称: DNA (5'-D(*CP*TP*CP*TP*TP*TP*(3DR)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ...
著者Pereira de Jesus-Tran, K, Serre, L, Zelwer, C, Castaing, B.
登録日2003-06-10
公開日2004-07-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA.
Nucleic Acids Res., 33, 2005
1Q39
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Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The WT enzyme at 2.8 resolution.
分子名称: CALCIUM ION, Endonuclease VIII, ZINC ION
著者Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G.
登録日2003-07-29
公開日2004-08-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
1Q3B
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Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The R252A mutant at 2.05 resolution.
分子名称: Endonuclease VIII, GLYCEROL, MAGNESIUM ION, ...
著者Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G.
登録日2003-07-29
公開日2004-08-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
1Q3C
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Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The E2A mutant at 2.3 resolution.
分子名称: Endonuclease VIII, GLYCEROL, MAGNESIUM ION, ...
著者Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G.
登録日2003-07-29
公開日2004-08-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility.
Nucleic Acids Res., 33, 2005
1QU2
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INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN
分子名称: ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, ...
著者Silvian, L.F, Wang, J, Steitz, T.A.
登録日1999-07-06
公開日1999-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin.
Science, 285, 1999
1QU3
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INSIGHTS INTO EDITING FROM AN ILE-TRNA SYNTHETASE STRUCTURE WITH TRNA(ILE) AND MUPIROCIN
分子名称: ISOLEUCYL-TRNA, ISOLEUCYL-TRNA SYNTHETASE, MUPIROCIN, ...
著者Silvian, L.F, Wang, J, Steitz, T.A.
登録日1999-07-06
公開日1999-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin.
Science, 285, 1999
1R2Y
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MutM (Fpg) bound to 8-oxoguanine (oxoG) containing DNA
分子名称: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
著者Fromme, J.C, Verdine, G.L.
登録日2003-09-30
公開日2003-10-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献DNA Lesion Recognition by the Bacterial Repair Enzyme MutM.
J.Biol.Chem., 278, 2003
1R2Z
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MutM (Fpg) bound to 5,6-dihydrouracil (DHU) containing DNA
分子名称: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*CP*AP*(DHU)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ...
著者Fromme, J.C, Verdine, G.L.
登録日2003-09-30
公開日2003-10-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献DNA Lesion Recognition by the Bacterial Repair Enzyme MutM.
J.Biol.Chem., 278, 2003
1TDZ
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Crystal Structure Complex Between the Lactococcus Lactis FPG (Mutm) and a FAPY-dG Containing DNA
分子名称: 5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', GLYCEROL, ...
著者Coste, F, Ober, M, Carell, T, Boiteux, S, Zelwer, C, Castaing, B.
登録日2004-05-24
公開日2004-09-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase
J.Biol.Chem., 279, 2004
1XC8
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CRYSTAL STRUCTURE COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND A FAPY-DG CONTAINING DNA
分子名称: 5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', Formamidopyrimidine-DNA glycosylase, ...
著者Coste, F, Ober, M, Carell, T, Boiteux, S, Zelwer, C, Castaing, B.
登録日2004-09-01
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase.
J.Biol.Chem., 279, 2004
2EA0
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Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli in complex with AP-site containing DNA substrate
分子名称: 5'-D(P*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3', Endonuclease VIII, ...
著者Golan, G, Zharov, D.O, Grollman, A.P, Shoham, G.
登録日2007-01-29
公開日2008-02-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrate and mutations of critical residues
To be Published
2F5N
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MutM crosslinked to undamaged DNA sampling A:T base pair IC1
分子名称: 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', GLYCEROL, ...
著者Banerjee, A, Santos, W.L, Verdine, G.L.
登録日2005-11-26
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a DNA glycosylase searching for lesions.
Science, 311, 2006

 

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