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4QEX
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Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217
分子名称: Antibody Heavy Chain, Antibody Light Chain, Erythrocyte-binding antigen-175
著者Chen, E, Paing, M.M, Salinas, N, Sim, B.K, Tolia, N.H.
登録日2014-05-19
公開日2014-06-04
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.
Plos Pathog., 9, 2013
4YFS
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BU of 4yfs by Molmil
Structure of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for malaria vaccine design
分子名称: Duffy receptor
著者Chen, E, Tolia, N.H.
登録日2015-02-25
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design.
Plos Negl Trop Dis, 9, 2015
5F3J
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BU of 5f3j by Molmil
Crystal structure of DBP in complex with inhibitory monoclonal antibody 2D10
分子名称: Antibody 2D10 single chain variable fragment, Duffy receptor
著者Chen, E, Salinas, N.D, Tolia, N.H.
登録日2015-12-02
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.001 Å)
主引用文献Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5X6N
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BU of 5x6n by Molmil
Structure of P. Knowlesi DBL Domain Capable of binding Human Duffy Antigen
分子名称: Duffy binding protein, SULFATE ION, octyl beta-D-glucopyranoside
著者Singh, S.K, Hora, R, Belrhali, H, Chitnis, C, Sharma, A.
登録日2017-02-22
公開日2017-03-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain
Nature, 439, 2006
6OAN
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BU of 6oan by Molmil
Structure of DBP in complex with human neutralizing antibody 053054
分子名称: Antibody 053054 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION
著者Urusova, D, Tolia, N.H.
登録日2019-03-18
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
1ZRO
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BU of 1zro by Molmil
Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose
分子名称: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
著者Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
登録日2005-05-19
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
1ZRL
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BU of 1zrl by Molmil
Crystal structure of EBA-175 Region II (RII)
分子名称: CHLORIDE ION, SULFATE ION, erythrocyte binding antigen region II
著者Tolia, N.H, Enemark, E.J, Sim, B.K, Joshua-Tor, L.
登録日2005-05-19
公開日2005-08-09
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the EBA-175 Erythrocyte Invasion Pathway of the Malaria Parasite Plasmodium falciparum.
Cell(Cambridge,Mass.), 122, 2005
6OAO
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Structure of DBP in complex with human neutralizing antibody 092096
分子名称: Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION
著者Urusova, D, Tolia, N.H.
登録日2019-03-18
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.497 Å)
主引用文献Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
4GF2
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BU of 4gf2 by Molmil
Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL)
分子名称: Erythrocyte binding antigen 140, GLYCEROL
著者Lin, D.H, Malpede, B.M, Batchelor, J.D, Tolia, N.H.
登録日2012-08-02
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion.
J.Biol.Chem., 287, 2012
4JNO
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BU of 4jno by Molmil
Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL) Region II in complex with sialyllactose
分子名称: BAEBL protein, N-acetyl-alpha-neuraminic acid
著者Tolia, N.H.
登録日2013-03-15
公開日2013-03-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular Basis for Sialic Acid-dependent Receptor Recognition by the Plasmodium falciparum Invasion Protein Erythrocyte-binding Antigen-140/BAEBL.
J.Biol.Chem., 288, 2013
3RRC
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BU of 3rrc by Molmil
Crystal Structure of Region II from Plasmodium vivax Duffy Binding Protein
分子名称: 1,2-ETHANEDIOL, Duffy receptor, PHOSPHATE ION
著者Tolia, N.H.
登録日2011-04-29
公開日2011-07-13
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC.
Nat.Struct.Mol.Biol., 18, 2011
6R2S
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BU of 6r2s by Molmil
The structure of Plasmodium vivax Duffy binding protein (PvDBP) bound to human antibody DB9
分子名称: Antibody DB9 heavy chain, Antibody DB9 light chain, Duffy receptor
著者Barber, N.M, Higgins, M.K.
登録日2019-03-18
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody.
Nat Microbiol, 4, 2019
6S8T
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BU of 6s8t by Molmil
Structure of the ICAM-1-binding PfEMP1 IT4var13 DBLbeta domain
分子名称: Erythrocyte membrane protein 1
著者Lennartz, F, Higgins, M.K.
登録日2019-07-10
公開日2019-09-25
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes.
Proc.Natl.Acad.Sci.USA, 116, 2019
3VUV
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BU of 3vuv by Molmil
Crystal structure of the merozoite surface protein MSPDBL2 from P. falciparum bound to zinc
分子名称: Erythrocyte membrane protein, putative, ZINC ION
著者Czabotar, P.E, Hodder, A.N, Clarke, O.B, Lin, C.S, Smith, B.J, Cowman, A.F.
登録日2012-07-09
公開日2012-08-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.114 Å)
主引用文献Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
3VUU
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BU of 3vuu by Molmil
Crystal structure of the merozoite surface protein MSPDBL2 from P. falciparum
分子名称: CHLORIDE ION, Erythrocyte membrane protein, putative
著者Czabotar, P.E, Hodder, A.N, Clarke, O.B, Lin, C.S, Smith, B.J, Cowman, A.F.
登録日2012-07-09
公開日2012-08-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum
J.Biol.Chem., 287, 2012
4K2U
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BU of 4k2u by Molmil
Crystal structure of PfEBA-175 F1 in complex with R218 antibody Fab fragment
分子名称: Antibody Heavy Chain, Antibody Light Chain, Erythrocyte binding antigen 175, ...
著者Tolia, N.H.
登録日2013-04-09
公開日2013-06-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.
Plos Pathog., 9, 2013
2WAU
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BU of 2wau by Molmil
Structure of DBL6 epsilon domain from VAR2CSA
分子名称: ERYTHROCYTE MEMBRANE PROTEIN 1 (PFEMP1)
著者Khunrae, P, Higgins, M.K.
登録日2009-02-16
公開日2009-08-18
最終更新日2014-12-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Comparison of Two Cspg-Binding Dbl Domains from the Var2Csa Protein Important in Malaria During Pregnancy.
J.Mol.Biol., 393, 2009
4NUU
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BU of 4nuu by Molmil
Heterotrimer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
分子名称: Duffy antigen/chemokine receptor, Duffy receptor
著者Tolia, N.H.
登録日2013-12-04
公開日2014-02-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC.
Plos Pathog., 10, 2014
4NUV
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BU of 4nuv by Molmil
Heterotetramer structure of Region II from Plasmodium vivax Duffy Binding Protein (PvDBP) bound to the ectodomain of the Duffy Antigen Receptor for Chemokines (DARC)
分子名称: Duffy antigen/chemokine receptor, Duffy receptor, GLYCEROL
著者Tolia, N.H.
登録日2013-12-04
公開日2014-02-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC.
Plos Pathog., 10, 2014
2Y8D
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BU of 2y8d by Molmil
STRUCTURE OF DBL6 EPSILON DOMAIN FROM VAR2CSA STRAIN FCR3
分子名称: 2-AMINO-ETHANETHIOL, BENZAMIDINE, ERYTHROCYTE MEMBRANE PROTEIN 1
著者Gangnard, S, Ramboarina, S, Lewit-Bentley, A, Bentley, G.A.
登録日2011-02-04
公開日2012-02-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural and Immunological Correlations between the Variable Blocks of the Var2Csa Domain Dbl6Epsilon from Two Plasmodium Falciparum Parasite Lines.
J.Mol.Biol., 425, 2013
4P1T
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BU of 4p1t by Molmil
Crystal structure of the DBL3X-DBL4epsilon double domain from the extracellular part of VAR2CSA PfEMP1 from Plasmodium falciparum
分子名称: Erythrocyte membrane protein 1
著者Gangnard, S, Dechavanne, S, Srivastava, A, Amirat, F, Gamain, B, Lewit-Bentley, A, Bentley, G.A.
登録日2014-02-27
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the DBL3X-DBL4 epsilon region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions.
Sci Rep, 5, 2015
3BQK
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BU of 3bqk by Molmil
Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate
分子名称: Erythrocyte membrane protein 1, GLYCEROL, SULFATE ION
著者Higgins, M.K.
登録日2007-12-20
公開日2008-06-24
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of a chondroitin sulfate-binding domain important in placental malaria.
J.Biol.Chem., 283, 2008
3BQI
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BU of 3bqi by Molmil
Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein
分子名称: Erythrocyte membrane protein 1, GLYCEROL
著者Higgins, M.K.
登録日2007-12-20
公開日2008-06-24
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of a chondroitin sulfate-binding domain important in placental malaria.
J.Biol.Chem., 283, 2008
3BQL
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BU of 3bql by Molmil
Structure of a chondroitin sulphate binding DBL3X domain from a var2csa encoded PfEMP1 protein
分子名称: Erythrocyte membrane protein 1, GLYCEROL, SULFATE ION
著者Higgins, M.K.
登録日2007-12-20
公開日2008-06-24
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of a chondroitin sulfate-binding domain important in placental malaria.
J.Biol.Chem., 283, 2008
3CPZ
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Crystal structure of VAR2CSA DBL3x domain in the presence of dodecasaccharide of CSA
分子名称: Erythrocyte membrane protein 1, SULFATE ION
著者Singh, K, Gittis, A.G, Nguyen, P, Gowda, D.C, Miller, L.H, Garboczi, D.N.
登録日2008-04-01
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.
Nat.Struct.Mol.Biol., 15, 2008

 

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