PDB: 322 件ウェブページステータス検索Chemie searchBIRD

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7MLB	Crystal structure of Thermus thermophilus transcription initiation complex with 5nt RNA 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*AP*GP*GP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*CP*AP*TP*CP*CP*CP*TP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-04-28 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
7MKJ	Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKI	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKE	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7MKD	Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Saecker, R.M, Darst, S.A, Chen, J. 登録日 2021-04-23 公開日 2021-09-29 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
7LQ4	Rr (RsiG)2-(c-di-GMP)2-WhiG complex 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), RsiG, WhiG 著者 Schumacher, M.A, Brennan, R.G. 登録日 2021-02-12 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Evolution of a sigma-(c-di-GMP)-anti-sigma switch. Proc.Natl.Acad.Sci.USA, 118, 2021
7L7B	Clostridioides difficile RNAP with fidaxomicin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Boyaci, H, Campbell, E.A, Darst, S.A, Chen, J. 登録日 2020-12-28 公開日 2022-02-02 最終更新日 2022-05-04 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile. Nature, 604, 2022
7KIN	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter 分子名称: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2021-11-03 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIM	Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor 分子名称: DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2021-11-03 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIF	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor 分子名称: DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2021-11-03 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KHI	Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp 分子名称: CHAPSO, DNA (28-MER), DNA (36-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-21 公開日 2020-10-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KHE	Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp 分子名称: CHAPSO, DNA (46-MER), DNA (54-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-21 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KHC	Escherichia coli RNA polymerase and rrnBP1 promoter closed complex 分子名称: CHAPSO, DNA (18 MER), DNA (63-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-20 公開日 2020-10-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.14 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KHB	Escherichia coli RNA polymerase and rrnBP1 promoter open complex 分子名称: CHAPSO, DNA (60-MER), DNA (64-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-20 公開日 2020-10-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7F75	Cryo-EM structure of Spx-dependent transcription activation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y, Shi, J. 登録日 2021-06-28 公開日 2021-10-13 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis of transcription activation by the global regulator Spx. Nucleic Acids Res., 49, 2021
7F0R	Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex 分子名称: DNA (70-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 He, D.W, You, L.L, Zhang, Y. 登録日 2021-06-06 公開日 2022-07-27 最終更新日 2023-02-08 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7EH2	Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer 分子名称: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH1	Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP 分子名称: 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH0	Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.808 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7DY6	A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W. 登録日 2021-01-20 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation. Biochem.Biophys.Res.Commun., 583, 2021
7CKQ	The cryo-EM structure of B. subtilis BmrR transcription activation complex 分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2020-07-18 公開日 2020-12-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription. Nat Commun, 11, 2020
7CHW	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-07-06 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
7C97	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-06-05 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
7C17	The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA 分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2020-05-02 公開日 2020-09-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.22 Å) 主引用文献 CueR activates transcription through a DNA distortion mechanism. Nat.Chem.Biol., 17, 2021
7BEG	Structures of class I bacterial transcription complexes 分子名称: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ... 著者 Ye, F.Z, Hao, M, Zhang, X.D. 登録日 2020-12-23 公開日 2021-12-01 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022

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