6Q2P
 
 | | Crystal structure of mouse viperin bound to cytidine triphosphate and S-adenosylhomocysteine | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. | | Deposit date: | 2019-08-08 | | Release date: | 2020-01-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.452 Å) | | Cite: | Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry, 59, 2020
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6IAZ
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6IAD
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6IA8
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6IA6
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6FZ6
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6FD2
 | | Radical SAM 1,2-diol dehydratase AprD4 in complex with its substrate paromamine | | Descriptor: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... | | Authors: | Liu, W.Q, Amara, P, Mouesca, J.M, Ji, X, Renoux, O, Martin, L, Zhang, C, Zhang, Q, Nicolet, Y. | | Deposit date: | 2017-12-21 | | Release date: | 2018-01-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | 1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility.
J. Am. Chem. Soc., 140, 2018
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6EFN
 | | Structure of a RiPP maturase, SkfB | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | Authors: | Grell, T.A.J, Drennan, C.L. | | Deposit date: | 2018-08-16 | | Release date: | 2018-10-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.291 Å) | | Cite: | Structure of a RiPP maturase, SkfB
J.Biol.Chem., 2018
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6DJT
 | | Structure of TYW1 with a lysine-pyruvate adduct bound | | Descriptor: | DI(HYDROXYETHYL)ETHER, FE2/S3 CLUSTER, GLYCEROL, ... | | Authors: | Grell, T.A.J, Drennan, C.L. | | Deposit date: | 2018-05-26 | | Release date: | 2018-06-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.
J. Am. Chem. Soc., 140, 2018
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6C8V
 | | X-ray structure of PqqE from Methylobacterium extorquens | | Descriptor: | Coenzyme PQQ synthesis protein E, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER | | Authors: | Gizzi, A.S, Grove, T.L, Bonanno, J.B, Almo, S.C. | | Deposit date: | 2018-01-25 | | Release date: | 2018-02-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE.
Biochemistry, 57, 2018
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6B4C
 | | Structure of Viperin from Trichoderma virens | | Descriptor: | CITRATE ANION, SULFATE ION, Viperin | | Authors: | Huang, R.H, Selvadurai, K. | | Deposit date: | 2017-09-26 | | Release date: | 2018-07-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.795 Å) | | Cite: | Reconstitution and substrate specificity for isopentenyl pyrophosphate of the antiviral radical SAM enzyme viperin.
J.Biol.Chem., 293, 2018
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5WHY
 | | Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides | | Descriptor: | CALCIUM ION, IRON/SULFUR CLUSTER, Radical SAM domain protein, ... | | Authors: | Grove, T.L, Himes, P, Bowers, A, Bonanno, J.B, Almo, S.C. | | Deposit date: | 2017-07-18 | | Release date: | 2017-07-26 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.692 Å) | | Cite: | Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides.
J. Am. Chem. Soc., 139, 2017
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5WGG
 | | Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides | | Descriptor: | CALCIUM ION, CteA, IRON/SULFUR CLUSTER, ... | | Authors: | Grove, T.L, Himes, P, Bowers, A, Bonanno, J.B, Almo, S.C. | | Deposit date: | 2017-07-14 | | Release date: | 2017-07-26 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.036 Å) | | Cite: | Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides.
J. Am. Chem. Soc., 139, 2017
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5VSM
 | | Crystal structure of viperin with bound [4Fe-4S] cluster, 5'-deoxyadenosine, and L-methionine | | Descriptor: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... | | Authors: | Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. | | Deposit date: | 2017-05-11 | | Release date: | 2017-06-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5VSL
 | | Crystal structure of viperin with bound [4Fe-4S] cluster and S-adenosylhomocysteine (SAH) | | Descriptor: | IRON/SULFUR CLUSTER, Radical S-adenosyl methionine domain-containing protein 2, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Fenwick, M.K, Li, Y, Cresswell, P, Modis, Y, Ealick, S.E. | | Deposit date: | 2017-05-11 | | Release date: | 2017-06-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.972 Å) | | Cite: | Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V1T
 | | Crystal structure of Streptococcus suis SuiB bound to precursor peptide SuiA | | Descriptor: | IRON/SULFUR CLUSTER, METHIONINE, Radical SAM, ... | | Authors: | Davis, K.M, Bacik, J.P, Ando, N. | | Deposit date: | 2017-03-02 | | Release date: | 2017-08-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V1S
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5V1Q
 | | Crystal structure of Streptococcus suis SuiB | | Descriptor: | IRON/SULFUR CLUSTER, Radical SAM | | Authors: | Davis, K.M, Bacik, J.P, Ando, N. | | Deposit date: | 2017-03-02 | | Release date: | 2017-08-30 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UL4
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5UL3
 | | Structure of Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB with aqua-cobalamin bound | | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | Authors: | Bridwell-Rabb, J, Drennan, C.L. | | Deposit date: | 2017-01-24 | | Release date: | 2017-04-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis.
Nature, 544, 2017
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5UL2
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5TH5
 | | Crystal Structure of QueE from Bacillus subtilis with 6-carboxypterin-5'-deoxyadenosyl ester bound | | Descriptor: | 5'-O-(2-amino-4-oxo-1,4-dihydropteridine-6-carbonyl)adenosine, 7-carboxy-7-deazaguanine synthase, IRON/SULFUR CLUSTER, ... | | Authors: | Grell, T.A.J, Dowling, D.P, Drennan, C.L. | | Deposit date: | 2016-09-29 | | Release date: | 2017-01-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.407 Å) | | Cite: | 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
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5TGS
 | | Crystal Structure of QueE from Bacillus subtilis with methionine bound | | Descriptor: | 7-carboxy-7-deazaguanine synthase, DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, ... | | Authors: | Grell, T.A.J, Dowling, D.P, Drennan, C.L. | | Deposit date: | 2016-09-28 | | Release date: | 2017-01-18 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.548 Å) | | Cite: | 7-Carboxy-7-deazaguanine Synthase: A Radical S-Adenosyl-l-methionine Enzyme with Polar Tendencies.
J. Am. Chem. Soc., 139, 2017
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5L7L
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5L7J
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