PDB: 66 件ウェブページステータス検索Chemie searchBIRD

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3ZXR	Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (3-(2-tert-butyl- 5-(pyridin-4-yl)-1H-imidazol-4-yl)quinoline) and L-methionine-S- sulfoximine phosphate. 分子名称: 3-(2-TERT-BUTYL-5-(PYRIDIN-4-YL)-1H-IMIDAZOL-4-YL)QUINOLINE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Nilsson, M.T, Mowbray, S.L. 登録日 2011-08-15 公開日 2012-04-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Trisubstituted Imidazoles as Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors. J.Med.Chem., 55, 2012
3ZXV	Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (4-(2-tert-butyl- 4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl)pyridin-2-amine) and L- methionine-S-sulfoximine phosphate 分子名称: 4-(2-TERT-BUTYL-4-(6-METHOXYNAPHTHALEN-2-YL)-3H-IMIDAZOL-4-YL)PYRIDIN-2-AMINE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Nilsson, M.T, Mowbray, S.L. 登録日 2011-08-16 公開日 2012-04-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Trisubstituted Imidazoles as Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors. J.Med.Chem., 55, 2012
2UU7	Crystal structure of apo glutamine synthetase from dog (Canis familiaris) 分子名称: CHLORIDE ION, GLUTAMINE SYNTHETASE, MAGNESIUM ION 著者 Krajewski, W.W, Jones, T.A, Mowbray, S.L. 登録日 2007-02-28 公開日 2007-10-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities for Drug and Herbicide Design. J.Mol.Biol., 375, 2008
4ACF	CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH IMIDAZOPYRIDINE INHIBITOR ((4-(6-BROMO-3-(BUTYLAMINO)IMIDAZO(1,2-A)PYRIDIN-2-YL)PHENOXY) ACETIC ACID) AND L-METHIONINE-S-SULFOXIMINE PHOSPHATE. 分子名称: CHLORIDE ION, GLUTAMINE SYNTHETASE 1, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... 著者 Nilsson, M.T, Mowbray, S.L. 登録日 2011-12-15 公開日 2012-10-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synthesis, Biological Evaluation and X-Ray Crystallographic Studies of Imidazo(1,2-A)Pyridine-Based Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors Medchemcomm, 3, 2012
2WGS	Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor. 分子名称: 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1 著者 Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L. 登録日 2009-04-27 公開日 2009-09-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors. J.Mol.Biol., 393, 2009
2WHI	Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor and L-methionine-S- sulfoximine phosphate. 分子名称: 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L. 登録日 2009-05-05 公開日 2009-09-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors. J.Mol.Biol., 393, 2009
4BAX	Crystal structure of glutamine synthetase from Streptomyces coelicolor 分子名称: GLUTAMINE SYNTHETASE, SODIUM ION 著者 Zeth, K. 登録日 2012-09-16 公開日 2013-03-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure of Glutamine Synthetase from Streptomyces Coelicolor To be Published
2GLS	REFINED ATOMIC MODEL OF GLUTAMINE SYNTHETASE AT 3.5 ANGSTROMS RESOLUTION 分子名称: GLUTAMINE SYNTHETASE, MANGANESE (II) ION 著者 Eisenberg, D, Almassy, R.J, Yamashita, M.M. 登録日 1989-05-19 公開日 1989-10-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Refined atomic model of glutamine synthetase at 3.5 A resolution. J.Biol.Chem., 264, 1989
1F1H	CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH THALLIUM IONS 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Gill, H.S, Eisenberg, D. 登録日 2000-05-19 公開日 2001-04-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition. Biochemistry, 40, 2001
1F52	CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM CO-CRYSTALLIZED WITH ADP 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE SYNTHETASE, ... 著者 Gill, H.S, Pfluegl, G.M.U, Eisenberg, D. 登録日 2000-06-12 公開日 2000-06-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition. Biochemistry, 40, 2001
1FPY	CRYSTAL STRUCTURE OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM WITH INHIBITOR PHOSPHINOTHRICIN 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE SYNTHETASE, MANGANESE (II) ION, ... 著者 Gill, H.S, Eisenberg, D. 登録日 2000-08-31 公開日 2001-04-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 The crystal structure of phosphinothricin in the active site of glutamine synthetase illuminates the mechanism of enzymatic inhibition. Biochemistry, 40, 2001
8OOZ	Glutamine synthetase from Methermicoccus shengliensis in complex with MgATP at 2.7 A resolution 分子名称: ADENOSINE-5'-TRIPHOSPHATE, FORMIC ACID, GLYCEROL, ... 著者 Mueller, M.-C, Lemaire, O.N, Wagner, T. 登録日 2023-04-06 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
8OOW	Glutamine synthetase from Methermicoccus shengliensis at a resolution of 2.64 A 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Glutamine synthetase, ... 著者 Mueller, M.-C, Lemaire, O.N, Wagner, T. 登録日 2023-04-06 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
8OOX	Glutamine synthetase from Methermicoccus shengliensis at a resolution of 3.09 A 分子名称: CITRIC ACID, GLYCEROL, Glutamine synthetase, ... 著者 Mueller, M.-C, Lemaire, O.N, Wagner, T. 登録日 2023-04-06 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
8PVG	Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV 分子名称: Glutamine synthetase 著者 McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. 登録日 2023-07-17 公開日 2023-11-29 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
1HTO	CRYSTALLOGRAPHIC STRUCTURE OF A RELAXED GLUTAMINE SYNTHETASE FROM MYCOBACTERIUM TUBERCULOSIS 分子名称: ADENOSINE MONOPHOSPHATE, CITRIC ACID, GLUTAMINE SYNTHETASE, ... 著者 Gill, H.S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) 登録日 2001-01-01 公開日 2002-07-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation. Biochemistry, 41, 2002
1HTQ	Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis 分子名称: ADENOSINE MONOPHOSPHATE, CITRIC ACID, MANGANESE (II) ION, ... 著者 Gill, H.S, Pfluegl, G.M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) 登録日 2001-01-01 公開日 2002-07-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation. Biochemistry, 41, 2002
8TFC	Cryo-EM structure of Methanosarcina mazie glutamine synthetase captured as partial oligomer 分子名称: Glutamine synthetase 著者 Schumacher, M.A. 登録日 2023-07-09 公開日 2023-11-15 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation. Nat Commun, 14, 2023
4IS4	The glutamine synthetase from the dicotyledonous plant M. truncatula is a decamer 分子名称: Glutamine synthetase 著者 Seabra, A.R, Carvalho, H, Pereira, P.J.B. 登録日 2013-01-16 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The structures of cytosolic and plastid-located glutamine synthetases from Medicago truncatula reveal a common and dynamic architecture. Acta Crystallogr.,Sect.D, 70, 2014
7U5N	Cryo-EM Structure of Glutamine Synthetase 分子名称: Glutamine synthetase, MANGANESE (II) ION 著者 Morgan, C.E, Yu, E.W, Zhang, Z. 登録日 2022-03-02 公開日 2022-12-14 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Toward structural-omics of the bovine retinal pigment epithelium. Cell Rep, 41, 2022
7V4J	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State I 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
7V4I	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb decamer assembly 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
7V4K	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State II 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
7V4L	Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State III 分子名称: Glutamine synthetase 著者 Xu, W, Chen, Y, Xing, Q, Huang, C. 登録日 2021-08-13 公開日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme. Elife, 10, 2021
7W85	Structural of the filamentous Escherichia coli glutamine synthetase 分子名称: Glutamine synthetase, NICKEL (II) ION 著者 Huang, P.-C, Chen, S.-K, Wu, K.-P. 登録日 2021-12-07 公開日 2022-04-06 最終更新日 2022-06-15 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural basis for the helical filament formation of Escherichia coli glutamine synthetase. Protein Sci., 31, 2022

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