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5UWP
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BU of 5uwp by Molmil
Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWO
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BU of 5uwo by Molmil
Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWH
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BU of 5uwh by Molmil
Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWT
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BU of 5uwt by Molmil
Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.342 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWS
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BU of 5uws by Molmil
Crystal Structure of X11L2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Amyloid beta A4 precursor protein-binding family A member 3, Exportin-1,Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5TQC
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BU of 5tqc by Molmil
Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4)
分子名称: 60S ribosomal protein L4-like protein, Transportin-1,Transportin-1
著者Huber, F.M, Hoelz, A.
登録日2016-10-23
公開日2017-02-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis for protection of ribosomal protein L4 from cellular degradation.
Nat Commun, 8, 2017
5J3V
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BU of 5j3v by Molmil
Crystal structure of human Karyopherin-beta2 bound to the histone H3 tail
分子名称: Histone H3, Transportin-1,Transportin-1
著者Soniat, M, Chook, Y.M.
登録日2016-03-31
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Karyopherin-beta 2 Recognition of a PY-NLS Variant that Lacks the Proline-Tyrosine Motif.
Structure, 24, 2016
5JLJ
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BU of 5jlj by Molmil
Crystal Structure of KPT8602 in complex with CRM1-Ran-RanBP1
分子名称: (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, CHLORIDE ION, Exportin-1, ...
著者Fung, H.Y, Chook, Y.M.
登録日2016-04-27
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies.
Leukemia, 30, 2016
4XRI
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BU of 4xri by Molmil
Crystal Structure of Importin Beta in an Ammonium Sulfate Condition
分子名称: GLYCEROL, Putative uncharacterized protein, SULFATE ION
著者Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A.
登録日2015-01-21
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Impact of the crystallization condition on importin-beta conformation.
Acta Crystallogr D Struct Biol, 72, 2016
4XRK
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BU of 4xrk by Molmil
Crystal Structure of Importin Beta in a Polyethylene Glycol Condition
分子名称: Importin Beta
著者Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A.
登録日2015-01-21
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Impact of the crystallization condition on importin-beta conformation.
Acta Crystallogr D Struct Biol, 72, 2016
5DIS
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BU of 5dis by Molmil
Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214
分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Monecke, T, Port, S.A, Dickmanns, A, Kehlenbach, R.H, Ficner, R.
登録日2015-09-01
公開日2015-11-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Cell Rep, 13, 2015
5DHF
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BU of 5dhf by Molmil
Crystal Structure of hRio2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Exportin-1, GLYCEROL, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-30
公開日2015-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.285 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DH9
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BU of 5dh9 by Molmil
Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered Nuclear Export Signal Peptide (PKINES-Flip3 mutant), Exportin-1, GLYCEROL, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-30
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DHA
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BU of 5dha by Molmil
Crystal Structure of CPEB4 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered Nuclear Export Signal Peptide (CPEB4 NES reverse mutant), Exportin-1, GLYCEROL, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-30
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DIF
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BU of 5dif by Molmil
Crystal Structure of CPEB4 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Cytoplasmic polyadenylation element-binding protein 4, Exportin-1, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-31
公開日2015-09-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DI9
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BU of 5di9 by Molmil
Crystal Structure of hRio2 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Engineered Nuclear Export Signal Peptide (hRio2 NES reverse mutant), Exportin-1, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-31
公開日2015-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
3WYF
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BU of 3wyf by Molmil
Crystal structure of Xpo1p-Yrb2p-Gsp1p-GTP complex
分子名称: Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, Gsp1p, ...
著者Koyama, M, Shirai, N, Matsuura, Y.
登録日2014-08-26
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural insights into how yrb2p accelerates the assembly of the xpo1p nuclear export complex
Cell Rep, 9, 2014
3WYG
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BU of 3wyg by Molmil
Crystal structure of Xpo1p-PKI-Gsp1p-GTP complex
分子名称: Exportin-1, GUANOSINE-5'-TRIPHOSPHATE, Gsp1p, ...
著者Koyama, M, Shirai, N, Matsuura, Y.
登録日2014-08-26
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural insights into how yrb2p accelerates the assembly of the xpo1p nuclear export complex
Cell Rep, 9, 2014
3W5K
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BU of 3w5k by Molmil
Crystal structure of Snail1 and importin beta complex
分子名称: Importin subunit beta-1, ZINC ION, Zinc finger protein SNAI1
著者Choi, S, Yamashita, E, Yasuhara, N, Song, J, Son, S.Y, Won, Y.H, Shin, Y.S, Sekimoto, T, Park, I.Y, Yoneda, Y, Lee, S.J.
登録日2013-01-30
公開日2014-03-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta.
Acta Crystallogr.,Sect.D, 70, 2014
4OO6
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BU of 4oo6 by Molmil
Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)
分子名称: RNA-binding protein 39, Transportin-1
著者Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
登録日2014-01-30
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)
to be published
4FQ3
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BU of 4fq3 by Molmil
Crystal structure of transportin/FUS-NLS
分子名称: Fusion (Involved in t(12;16) in malignant liposarcoma), Transportin-1
著者Gong, W, Niu, C, Jia, M, Gao, F.
登録日2012-06-25
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of transportin/FUS-NLS
To be Published
4BSM
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BU of 4bsm by Molmil
Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.5A
分子名称: EXPORTIN-1
著者Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C.
登録日2013-06-10
公開日2013-07-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
4BSN
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BU of 4bsn by Molmil
Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.1A
分子名称: EXPORTIN-1
著者Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C.
登録日2013-06-11
公開日2013-07-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
3ZJY
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BU of 3zjy by Molmil
Crystal Structure of Importin 13 - RanGTP - eIF1A complex
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL, GTP-BINDING NUCLEAR PROTEIN RAN, ...
著者Gruenwald, M, Lazzaretti, D, Bono, F.
登録日2013-01-21
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013
3ZKV
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BU of 3zkv by Molmil
Importin13 cytosolic state
分子名称: CADMUS
著者Gruenwald, M, Lazzaretti, D, Bono, F.
登録日2013-01-24
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013

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件を2024-05-15に公開中

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