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7D0M
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Crystal structure of mouse CRY1 with bound cryoprotectant
分子名称: Cryptochrome-1, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2020-09-11
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
6X24
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BU of 6x24 by Molmil
Structural basis of plant blue light photoreceptor
分子名称: Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
著者Palayam, M, Ganapathy, J, Guercio, M.A, Shabek, N.
登録日2020-05-19
公開日2020-12-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural insights into photoactivation of plant Cryptochrome-2.
Commun Biol, 4, 2021
6WTB
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Sort-Tagged Drosophila Cryptochrome
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION
著者Schneps, C.M, Crane, B.R.
登録日2020-05-02
公開日2021-05-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome.
Commun Biol, 4, 2021
6M79
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Cryo-EM structure of Arabidopsis CRY under blue light-mediated activation
分子名称: ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
著者Ma, L, Guan, Z.Y, Yin, P.
登録日2020-03-18
公開日2020-10-14
最終更新日2021-08-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the photoactivation of Arabidopsis CRY2.
Nat.Plants, 6, 2020
6LZ7
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Tetrameric structure of ZmCRY1a PHR domain
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE
著者Shao, K, Zhang, X, Zhang, P.
登録日2020-02-18
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.59936166 Å)
主引用文献The oligomeric structures of plant cryptochromes.
Nat.Struct.Mol.Biol., 27, 2020
6LZ3
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Structure of cryptochrome in active conformation
分子名称: Cryptochrome2, FLAVIN-ADENINE DINUCLEOTIDE
著者Shao, K, Zhang, X, Zhang, P.
登録日2020-02-18
公開日2020-04-29
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The oligomeric structures of plant cryptochromes.
Nat.Struct.Mol.Biol., 27, 2020
6LUE
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Crystal structure of mouse Cryptochrome 1 in complex with compound KL201
分子名称: 2-bromanyl-N-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)benzamide, Cryptochrome-1
著者Miller, S, Aikawa, Y, Hirota, T.
登録日2020-01-27
公開日2020-06-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals.
Cell Chem Biol, 27, 2020
6KX8
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Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX7
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Crystal structure of mouse Cryptochrome 1 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX5
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Crystal structure of mouse Cryptochrome 1 in complex with KL044 compound
分子名称: 2-carbazol-9-yl-N-(2-chloranyl-6-cyano-phenyl)ethanamide, Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX6
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Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound
分子名称: Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX4
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Crystal structure of mouse Cryptochrome 1 apo form
分子名称: Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6PTZ
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Crystal structure of pigeon Cryptochrome 4 mutant Y319D in complex with flavin adenine dinucleotide
分子名称: Cryptochrome-1, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Zoltowski, B.D, Chelliah, Y, Wickramaratne, A.C, Jarocha, L, Karki, N, Mouritsen, H, Hore, P.J, Hibbs, R.E, Green, C.B, Takahashi, J.S.
登録日2019-07-16
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PU0
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Pigeon Cryptochrome4 bound to flavin adenine dinucleotide
分子名称: 1,2-ETHANEDIOL, Cryptochrome-1, DI(HYDROXYETHYL)ETHER, ...
著者Zoltowski, B.D, Chelliah, Y, Wickramaratne, A.C, Jarocha, L, Karki, N, Mouritsen, H, Hore, P.J, Hibbs, R.E, Green, C.B, Takahashi, J.S.
登録日2019-07-16
公開日2019-09-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8979 Å)
主引用文献Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon.
Proc.Natl.Acad.Sci.USA, 116, 2019
6K8K
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Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex
分子名称: ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Wang, X, Ma, L, Guan, Z, Yin, P.
登録日2019-06-12
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
6K8I
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Crystal structure of Arabidopsis thaliana CRY2
分子名称: Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
著者Ma, L, Wang, X, Guan, Z, Yin, P.
登録日2019-06-12
公開日2020-05-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
6OF7
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BU of 6of7 by Molmil
Crystal structure of the CRY1-PER2 complex
分子名称: Cryptochrome-1, Period circadian protein homolog 2
著者Michael, A.K, Fribourgh, J.L, Tripathi, S.M, Partch, C.L.
登録日2019-03-28
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.
Elife, 9, 2020
5ZM0
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BU of 5zm0 by Molmil
X-ray structure of animal-like Cryptochrome from Chlamydomonas reinhardtii
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Cryptochrome photoreceptor, ...
著者Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Gusti Ngurah Putu, E.P, Maestre-Reyna, M, Tsai, M.-D, Yamamoto, J, Mittag, M, Essen, L.-O.
登録日2018-03-31
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii
Nucleic Acids Res., 46, 2018
6FN3
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X-ray structure of animal-like Cryptochrome from Chlamydomonas reinhardtii
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cryptochrome photoreceptor, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Yamamoto, J, Mittag, M, Essen, L.-O.
登録日2018-02-02
公開日2018-08-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii.
Nucleic Acids Res., 46, 2018
6FN0
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The animal-like Cryptochrome from Chlamydomonas reinhardtii in complex with 6-4 DNA
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Cryptochrome photoreceptor, ...
著者Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Yamamoto, J, Mittag, M, Essen, L.-O.
登録日2018-02-02
公開日2018-08-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii.
Nucleic Acids Res., 46, 2018
6FN2
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X-ray structure of animal-like Cryptochrome from Chlamydomonas reinhardtii
分子名称: 8-HYDROXY-10-(D-RIBO-2,3,4,5-TETRAHYDROXYPENTYL)-5-DEAZAISOALLOXAZINE, CHLORIDE ION, Cryptochrome photoreceptor, ...
著者Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Yamamoto, J, Mittag, M, Essen, L.-O.
登録日2018-02-02
公開日2018-08-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii.
Nucleic Acids Res., 46, 2018
5T5X
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High resolution structure of mouse Cryptochrome 1
分子名称: CHLORIDE ION, Cryptochrome-1
著者Michael, A.K, Tripathi, S, Partch, C.L.
登録日2016-08-31
公開日2017-02-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4U8H
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Crystal Structure of Mammalian Period-Cryptochrome Complex
分子名称: Cryptochrome-2, Period circadian protein homolog 2, ZINC ION
著者Nangle, S.N, Rosensweig, C, Koike, N, Tei, H, Takahashi, J.S, Green, C.B, Zheng, N.
登録日2014-08-03
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex.
Elife, 3, 2014
4U63
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Crystal structure of a bacterial class III photolyase from Agrobacterium tumefaciens at 1.67A resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, DNA photolyase, ...
著者Scheerer, P, Zhang, F, Kalms, J, von Stetten, D, Krauss, N, Oberpichler, I, Lamparter, T.
登録日2014-07-26
公開日2015-03-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献The Class III Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals a New Antenna Chromophore Binding Site and Alternative Photoreduction Pathways.
J.Biol.Chem., 290, 2015
4CT0
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Crystal Structure of Mouse Cryptochrome1 in Complex with Period2
分子名称: CHLORIDE ION, CRYPTOCHROME-1, HEXAETHYLENE GLYCOL, ...
著者Schmalen, I, Rajan Prabu, J, Benda, C, Wolf, E.
登録日2014-03-11
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Interaction of Circadian Clock Proteins Cry1 and Per2 is Modulated by Zinc Binding and Disulfide Bond Formation.
Cell(Cambridge,Mass.), 157, 2014

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