PDB: 297 件ウェブページステータス検索Chemie searchBIRD

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4E0B	2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6 分子名称: ACETATE ION, Malate dehydrogenase 著者 Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-03-02 公開日 2012-03-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6 To be Published
4I9H	Crystal structure of rabbit LDHA in complex with AP28669 分子名称: 1-O-[3-(5-carboxypyridin-2-yl)-5-fluorophenyl]-6-O-[4-({[(5-carboxypyridin-2-yl)sulfanyl]acetyl}amino)-2-chloro-5-methoxyphenyl]-D-mannitol, L-lactate dehydrogenase A chain 著者 Zhou, T, Stephan, Z.G, Kohlmann, A, Li, F, Commodore, L, Greenfield, M.T, Shakespeare, W.C, Zhu, X, Dalgarno, D.C. 登録日 2012-12-05 公開日 2013-01-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors. J.Med.Chem., 56, 2013
4WLF	Crystal structure of L-malate bound MDH2 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-malate bound MDH2 To Be Published
3PQE	Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation 分子名称: L-lactate dehydrogenase 著者 Zhang, Y, Garavito, R.M. 登録日 2010-11-26 公開日 2011-12-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation To be Published
9LDB	DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK 分子名称: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... 著者 Dunn, C.R, Holbrook, J.J, Muirhead, H. 登録日 1991-11-26 公開日 1993-10-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Design and synthesis of new enzymes based on the lactate dehydrogenase framework. Philos.Trans.R.Soc.London,Ser.B, 332, 1991
1GUY	Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases 分子名称: CADMIUM ION, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Dalhus, B, Sarinen, M, Sauer, U.H, Eklund, P, Johansson, K, Karlsson, A, Ramaswamy, S, Bjork, A, Synstad, B, Naterstad, K, Sirevag, R, Eklund, H. 登録日 2002-02-04 公開日 2002-02-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases J.Mol.Biol., 318, 2002
2V6M	Crystal structure of lactate dehydrogenase from Thermus Thermophilus HB8 (Apo form) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-LACTATE DEHYDROGENASE 著者 Coquelle, N, Fioravanti, E, Weik, M, Vellieux, F. 登録日 2007-07-19 公開日 2007-09-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments. J. Mol. Biol., 374, 2007
1HYH	CRYSTAL STRUCTURE OF L-2-HYDROXYISOCAPROATE DEHYDROGENASE FROM LACTOBACILLUS CONFUSUS AT 2.2 ANGSTROMS RESOLUTION-AN EXAMPLE OF STRONG ASYMMETRY BETWEEN SUBUNITS 分子名称: L-2-HYDROXYISOCAPROATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION 著者 Niefind, K, Hecht, H.-J, Schomburg, D. 登録日 1995-06-05 公開日 1995-10-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-2-hydroxyisocaproate dehydrogenase from Lactobacillus confusus at 2.2 A resolution. An example of strong asymmetry between subunits. J.Mol.Biol., 251, 1995
7BYA	Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) complexed with Oxaloacetic Acid (OAA) and Adenosine 5'-Diphosphoribose (APR) 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Malate dehydrogenase, OXALOACETATE ION 著者 Shimozawa, Y, Nakamura, T, Himiyama, T, Nishiya, Y. 登録日 2020-04-22 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus. J.Biochem., 170, 2021
7BY9	Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) complexed with Oxaloacetic Acid (OAA) and Nicotinamide Adenine Dinucleotide (NAD) 分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALOACETATE ION 著者 Shimozawa, Y, Nakamura, T, Himiyama, T, Nishiya, Y. 登録日 2020-04-22 公開日 2021-03-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis and reaction mechanism of malate dehydrogenase from Geobacillus stearothermophilus. J.Biochem., 170, 2021
4ZVV	Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140 分子名称: (2~{R})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Li, Y, Chen, Z, Eigenbrot, C. 登録日 2015-05-18 公開日 2016-05-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition. Nat.Chem.Biol., 12, 2016
3P7M	Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4 分子名称: Malate dehydrogenase, PHOSPHATE ION 著者 Osinski, T, Cymborowski, M, Zimmerman, M.D, Gordon, E, Grimshaw, S, Skarina, T, Chruszcz, M, Savchenko, A, Anderson, W, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-10-12 公開日 2010-10-20 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of putative lactate dehydrogenase from Francisella tularensis subsp. tularensis SCHU S4 To be Published
2HJR	Crystal Structure of Cryptosporidium parvum malate dehydrogenase 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CITRIC ACID, Malate dehydrogenase 著者 Wernimont, A.K, Dong, A, Lew, J, Hassani, A, Ren, H, Qiu, W, Kozieradzki, I, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) 登録日 2006-06-30 公開日 2006-08-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
1PZF	T.gondii LDH1 ternary complex with APAD+ and oxalate 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, OXALATE ION, lactate dehydrogenase 著者 Kavanagh, K.L, Elling, R.A, Wilson, D.K. 登録日 2003-07-10 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use. Biochemistry, 43, 2004
4ND4	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
2PWZ	Crystal structure of the apo form of E.Coli malate dehydrogenase 分子名称: Malate dehydrogenase 著者 Soderberg, C.A.G, Clarke, T.A, Richardson, D.J, Hemmings, A.M. 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The X-ray crystal structure of the apo form of E.Coli malate dehydrogenase in space group C2 To be Published
6KA0	Silver-bound E.coli Malate dehydrogenase 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Malate dehydrogenase, SILVER ION 著者 Wang, H, Wang, M, Sun, H. 登録日 2019-06-19 公開日 2020-06-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 MDH is a major silver target in E. coli To Be Published
4I8X	Crystal structure of rabbit LDHA in complex with AP27460 分子名称: 6-phenylpyridine-3-carboxylic acid, L-lactate dehydrogenase A chain 著者 Zhou, T, Stephan, Z.G, Kohlmann, A, Li, F, Commodore, L, Greenfield, M.T, Zhu, X, Dalgarno, D.C. 登録日 2012-12-04 公開日 2013-01-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors. J.Med.Chem., 56, 2013
3GVI	Crystal structure of Lactate/malate dehydrogenase from Brucella melitensis in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Malate dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-03-31 公開日 2009-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of Lactate/malate dehydrogenase from Brucella melitensis in complex with ADP To be Published
2J5R	2.25 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after second radiation burn (radiation damage series) 分子名称: CHLORIDE ION, MALATE DEHYDROGENASE 著者 Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M. 登録日 2006-09-19 公開日 2006-09-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment. J.Synchrotron Radiat., 14, 2007
4WLN	Crystal structure of apo MDH2 分子名称: Malate dehydrogenase, mitochondrial, PHOSPHATE ION 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of apo MDH2 To Be Published
7X1L	Malate dehydrogenase from Geobacillus stearothermophilus (gs-MDH) delta E311 mutant complexed with Nicotinamide Adenine Dinucleotide (NAD+) 分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Shimozawa, Y, Himiyama, T, Nakamura, T, Nishiya, Y. 登録日 2022-02-24 公開日 2022-10-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Reducing substrate inhibition of malate dehydrogenase from Geobacillus stearothermophilus by C-terminal truncation. Protein Eng.Des.Sel., 35, 2022
5Z3W	Malate dehydrogenase binds silver at C113 分子名称: Malate dehydrogenase, SILVER ION 著者 Wang, H, Wang, M, Sun, H. 登録日 2018-01-09 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm Chem Sci, 2020
5ES3	Co-crystal structure of LDH liganded with oxamate 分子名称: L-lactate dehydrogenase A chain, OXAMIC ACID 著者 Nowicki, M.W, Wear, M.A, McNae, I.W, Blackburn, E.A. 登録日 2015-11-16 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 A Streamlined, Automated Protocol for the Production of Milligram Quantities of Untagged Recombinant Rat Lactate Dehydrogenase A Using AKTAxpressTM. Plos One, 10, 2015
1EZ4	CRYSTAL STRUCTURE OF NON-ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS PENTOSUS AT 2.3 ANGSTROM RESOLUTION 分子名称: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Uchikoba, H, Fushinobu, S, Wakagi, T, Konno, M, Taguchi, H, Matsuzawa, H. 登録日 2000-05-10 公開日 2001-12-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces. Proteins, 46, 2002

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