PDB: 297 件ウェブページステータス検索Chemie searchBIRD

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5NUF	Cytosolic Malate Dehydrogenase 1 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Young, D, Messens, J, Huang, J, Reichheld, J.-P. 登録日 2017-04-29 公開日 2018-01-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
1BDM	THE STRUCTURE AT 1.8 ANGSTROMS RESOLUTION OF A SINGLE SITE MUTANT (T189I) OF MALATE DEHYDROGENASE FROM THERMUS FLAVUS WITH INCREASED ENZYMATIC ACTIVITY 分子名称: BETA-6-HYDROXY-1,4,5,6-TETRHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MALATE DEHYDROGENASE 著者 Kelly, C.A, Birktoft, J.J. 登録日 1993-02-16 公開日 1994-12-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus. Biochemistry, 32, 1993
1T26	Plasmodium falciparum lactate dehydrogenase complexed with NADH and 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase 著者 Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. 登録日 2004-04-20 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
3H3J	Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate 分子名称: GLYCEROL, L-lactate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Ho, M.-C, Almo, S.C, Schramm, V.L. 登録日 2009-04-16 公開日 2010-04-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate To be Published
1U5A	Plasmodium falciparum lactate dehydrogenase complexed with 3,5-dihydroxy-2-naphthoic acid 分子名称: 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase 著者 Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. 登録日 2004-07-27 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol.Biochem.Parasitol., 142, 2005
1UXK	Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface 分子名称: CADMIUM ION, CHLORIDE ION, MALATE DEHYDROGENASE, ... 著者 Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. 登録日 2004-02-25 公開日 2004-08-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
3D0O	Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus 分子名称: L-lactate dehydrogenase 1 著者 Ho, M, Gutierrez, J.A, Almo, S.C, Schramm, V.L. 登録日 2008-05-02 公開日 2009-05-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus To be Published
3D4P	Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate 分子名称: L-lactate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID 著者 Schramm, V.L, Almo, S.C, Gutierrez, J.A, Ho, M. 登録日 2008-05-14 公開日 2009-06-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate To be Published
7DBK	Crystal structure of human LDHB in complex with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase B chain 著者 Sogabe, S, Miwa, M. 登録日 2020-10-20 公開日 2021-10-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep, 11, 2021
4BGV	1.8 A resolution structure of the malate dehydrogenase from Picrophilus torridus in its apo form 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Talon, R, Madern, D, Girard, E. 登録日 2013-03-28 公開日 2014-04-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.811 Å) 主引用文献 Insight Into Structural Evolution of Extremophilic Proteins To be Published
1MLD	REFINED STRUCTURE OF MITOCHONDRIAL MALATE DEHYDROGENASE FROM PORCINE HEART AND THE CONSENSUS STRUCTURE FOR DICARBOXYLIC ACID OXIDOREDUCTASES 分子名称: CITRIC ACID, MALATE DEHYDROGENASE 著者 Gleason, W.B, Fu, Z, Birktoft, J.J, Banaszak, L.J. 登録日 1994-01-24 公開日 1995-01-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Refined crystal structure of mitochondrial malate dehydrogenase from porcine heart and the consensus structure for dicarboxylic acid oxidoreductases. Biochemistry, 33, 1994
7NAY	Crystal structure of lactate dehydrogenase from Selenomonas ruminantium with NADH. 分子名称: 1,2-ETHANEDIOL, BORIC ACID, L-lactate dehydrogenase, ... 著者 Bertrand, Q, Robin, A, Girard, E, Madern, D. 登録日 2021-01-25 公開日 2021-02-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases. J.Struct.Biol., 215, 2023
7QOZ	Crystal structure of NAD-bound glycosomal malate dehydrogenase from Trypanosoma cruzi 分子名称: GLYCEROL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Sonani, R.R, Dubin, G. 登録日 2021-12-30 公開日 2023-07-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of NAD-bound glycosomal malate dehydrogenase from Trypanosoma cruzi To Be Published
4PLW	Crystal structure of ancestral apicomplexan malate dehydrogenase with lactate. 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PHOSPHATE ION, malate dehydrogenase 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-19 公開日 2014-07-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
6PBL	Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1 分子名称: Malate dehydrogenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-06-14 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of Malate dehydrogenase from Legionella pneumophila Philadelphia 1 TO BE PUBLISHED
4PLV	Crystal structure of ancestral apicomplexan malate dehydrogenase with lactate. 分子名称: (2S)-2-HYDROXYPROPANOIC ACID, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, malate dehydrogenase 著者 Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. 登録日 2014-05-19 公開日 2014-07-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
1T2E	Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase, ... 著者 Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. 登録日 2004-04-21 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
5KKC	l-lactate dehydrogenase from rabbit muscle with the inhibitor 6DHNAD 分子名称: L-lactate dehydrogenase A chain, SULFATE ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(5-aminocarbonyl-2~{H}-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 著者 Meneely, K.M, Moran, G.R, Lamb, A.L. 登録日 2016-06-21 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.859 Å) 主引用文献 Ligand binding phenomena that pertain to the metabolic function of renalase. Arch.Biochem.Biophys., 612, 2016
2CMD	THE CRYSTAL STRUCTURE OF E.COLI MALATE DEHYDROGENASE: A COMPLEX OF THE APOENZYME AND CITRATE AT 1.87 ANGSTROMS RESOLUTION 分子名称: CITRIC ACID, MALATE DEHYDROGENASE 著者 Hall, M.D, Banaszak, L.J. 登録日 1992-09-23 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal structure of Escherichia coli malate dehydrogenase. A complex of the apoenzyme and citrate at 1.87 A resolution. J.Mol.Biol., 226, 1992
4AJ1	rat LDHA in complex with N-(2-(methylamino)-1,3-benzothiazol-6-yl) acetamide 分子名称: GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, MALONATE ION, ... 著者 Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G. 登録日 2012-02-15 公開日 2012-03-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
5NQQ	Rabbit Muscle L-lactate dehydrogenase in complex with NADH and oxaloacetate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain, OXALOACETATE ION, ... 著者 Luisi, B.F, Olin-Sandoval, V. 登録日 2017-04-20 公開日 2017-06-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.872 Å) 主引用文献 The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization. Nat Commun, 8, 2017
4B7U	PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH BICINE 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, BICINE, ... 著者 Birkinshaw, R.W, Brady, R.L. 登録日 2012-08-22 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The Crystal Structure of Plasmodium Falciparum L- Lactate Dehydrogenase in Complex with a Novel Bicine Ligand To be Published
6K13	Crystal Structure Basis for BmLDH Complex 分子名称: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID 著者 Long, Y, Shen, Z. 登録日 2019-05-09 公開日 2019-10-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis. Faseb J., 33, 2019
6QSS	Crystal Structure of Ignicoccus islandicus malate dehydrogenase co-crystallized with 10 mM Tb-Xo4 分子名称: CHLORIDE ION, Malate dehydrogenase, TERBIUM(III) ION, ... 著者 Roche, J, Girard, E, Madern, D. 登録日 2019-02-21 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 SOLUTION SCATTERING (1.892 Å), X-RAY DIFFRACTION 主引用文献 The archaeal LDH-like malate dehydrogenase from Ignicoccus islandicus displays dual substrate recognition, hidden allostery and a non-canonical tetrameric oligomeric organization. J.Struct.Biol., 208, 2019
4JNK	Lactate Dehydrogenase A in complex with inhibitor compound 22 分子名称: (2R)-2-{[5-cyano-4-(3,4-dichlorophenyl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(4-sulfamoylphenyl)propanamide, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Eigenbrot, C, Ultsch, M. 登録日 2013-03-15 公開日 2013-05-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.896 Å) 主引用文献 Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 23, 2013

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