6MSH
| Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Mao, Y.D. | Deposit date: | 2018-10-16 | Release date: | 2018-11-21 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
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7QXN
| Proteasome-ZFAND5 Complex Z+A state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-26 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
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5T0C
| Structural basis for dynamic regulation of the human 26S proteasome | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | Deposit date: | 2016-08-15 | Release date: | 2016-10-19 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for dynamic regulation of the human 26S proteasome. Proc.Natl.Acad.Sci.USA, 113, 2016
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5M32
| Human 26S proteasome in complex with Oprozomib | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H. | Deposit date: | 2016-10-14 | Release date: | 2017-07-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nat Commun, 8, 2017
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5L4K
| The human 26S proteasome lid | Descriptor: | 26S proteasome complex subunit DSS1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | Authors: | Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F. | Deposit date: | 2016-05-25 | Release date: | 2016-09-07 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the human 26S proteasome at a resolution of 3.9 angstrom. Proc.Natl.Acad.Sci.USA, 113, 2016
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7QYB
| Proteasome-ZFAND5 Complex Z-C state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
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7QXW
| Proteasome-ZFAND5 Complex Z+D state | Descriptor: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
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7QXU
| Proteasome-ZFAND5 Complex Z+C state | Descriptor: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
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7QXX
| Proteasome-ZFAND5 Complex Z+E state | Descriptor: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
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5T0G
| Structural basis for dynamic regulation of the human 26S proteasome | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | Deposit date: | 2016-08-16 | Release date: | 2016-10-19 | Last modified: | 2016-11-30 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural basis for dynamic regulation of the human 26S proteasome. Proc.Natl.Acad.Sci.USA, 113, 2016
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5GJQ
| Structure of the human 26S proteasome bound to USP14-UbAl | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. | Deposit date: | 2016-07-01 | Release date: | 2016-08-17 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | An atomic structure of the human 26S proteasome. Nat. Struct. Mol. Biol., 23, 2016
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7QY7
| Proteasome-ZFAND5 Complex Z-A state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
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7QYA
| Proteasome-ZFAND5 Complex Z-B state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
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6WJD
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5T0H
| Structural basis for dynamic regulation of the human 26S proteasome | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | Deposit date: | 2016-08-16 | Release date: | 2016-10-19 | Last modified: | 2016-11-30 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Structural basis for dynamic regulation of the human 26S proteasome. Proc.Natl.Acad.Sci.USA, 113, 2016
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5LN3
| The human 26S Proteasome at 6.8 Ang. | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Schweitzer, A, Beck, F, Sakata, E, Unverdorben, P. | Deposit date: | 2016-08-03 | Release date: | 2017-03-22 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol. Cell Proteomics, 16, 2017
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5T0I
| Structural basis for dynamic regulation of the human 26S proteasome | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | Deposit date: | 2016-08-16 | Release date: | 2016-10-19 | Last modified: | 2016-11-30 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structural basis for dynamic regulation of the human 26S proteasome. Proc.Natl.Acad.Sci.USA, 113, 2016
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5T0J
| Structural basis for dynamic regulation of the human 26S proteasome | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | Authors: | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | Deposit date: | 2016-08-16 | Release date: | 2016-10-19 | Last modified: | 2016-11-30 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structural basis for dynamic regulation of the human 26S proteasome. Proc.Natl.Acad.Sci.USA, 113, 2016
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6EPF
| Ground state 26S proteasome (GS1) | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | Authors: | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | Deposit date: | 2017-10-11 | Release date: | 2018-02-07 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (11.8 Å) | Cite: | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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6EPC
| Ground state 26S proteasome (GS2) | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | Authors: | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | Deposit date: | 2017-10-11 | Release date: | 2018-02-07 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (12.3 Å) | Cite: | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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6EPE
| Substrate processing state 26S proteasome (SPS2) | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | Authors: | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | Deposit date: | 2017-10-11 | Release date: | 2018-02-07 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (12.8 Å) | Cite: | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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6EPD
| Substrate processing state 26S proteasome (SPS1) | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | Authors: | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | Deposit date: | 2017-10-11 | Release date: | 2018-02-07 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (15.4 Å) | Cite: | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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5IXF
| Solution structure of the STAM2 SH3 with AMSH derived peptide complex | Descriptor: | STAM-binding protein, Signal transducing adapter molecule 2 | Authors: | Hologne, M, Cantrelle, F.X, Trivelli, X, Walker, O. | Deposit date: | 2016-03-23 | Release date: | 2016-12-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin. J.Mol.Biol., 428, 2016
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2KLZ
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2KDF
| NMR structure of minor S5a (196-306):K48 linked diubiquitin species | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin | Authors: | Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J. | Deposit date: | 2009-01-06 | Release date: | 2009-09-01 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13. Mol.Cell, 35, 2009
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