PDB: 125 resultsInfo pagesStatus searchChemie searchBIRD

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8VAT	Structure of the E. coli clamp loader bound to the beta clamp in a Open-RNAp/t conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAM	Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAP	Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAR	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAQ	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAL	Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAS	Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... Authors: Landeck, J.T, Kelch, B.A. Deposit date: 2023-12-11 Release date: 2024-03-27 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
4K3Q	E. coli sliding clamp in complex with AcQLDAF Descriptor: (ACE)QLDAF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K74	The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor. Descriptor: DNA polymerase III subunit beta, UmuC peptide Authors: Patoli, A.A, Winter, J.A, Bunting, K.A. Deposit date: 2013-04-16 Release date: 2013-07-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor. Bmc Struct.Biol., 13, 2013
4K3O	E. coli sliding clamp in complex with AcQADLF Descriptor: (ACE)QADLF, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3K	E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-10 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3P	E. coli sliding clamp in complex with AcQLALF Descriptor: (ACE)QLALF, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3R	E. coli sliding clamp in complex with AcQLDLA Descriptor: (ACE)QLDLA, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3L	E. coli sliding clamp in complex with AcLF dipeptide Descriptor: 1,2-ETHANEDIOL, ACETYL GROUP, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-10 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3S	E. coli sliding clamp in P1 crystal space group Descriptor: CALCIUM ION, DNA polymerase III subunit beta, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3M	E.coli sliding clamp in complex with AcALDLF peptide Descriptor: ALDLF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4MJR	E. coli sliding clamp in complex with (S)-Carprofen Descriptor: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-09-04 Release date: 2013-09-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.62 Å) Cite: DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
4N94	E. coli sliding clamp in complex with 3,4-difluorobenzamide Descriptor: 1,2-ETHANEDIOL, 3,4-difluorobenzamide, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N98	E. coli sliding clamp in complex with 4'-fluorobiphenyl-4-carboxylic acid Descriptor: 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N9A	E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid Descriptor: (1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N97	E. coli sliding clamp in complex with 5-nitroindole Descriptor: 5-nitro-1H-indole, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N99	E. coli sliding clamp in complex with 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid Descriptor: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N95	E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione Descriptor: 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N96	E. coli sliding clamp in complex with 6-nitroindazole Descriptor: 6-NITROINDAZOLE, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4MJP	E. coli sliding clamp in complex with (R)-Vedaprofen Descriptor: (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-09-04 Release date: 2013-09-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.855 Å) Cite: DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014

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